iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000047821.16	ENSMUST00000055006.11	ENSMUSP00000055542.5
ENSMUSG00000047821.16	ENSMUST00000072639.9	ENSMUSP00000072432.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	18248090

Organism

Mus musculus

Functional Description
(View)

Belongs to the TRIM/RBCC family.

Protein Sequence
(Fasta)

MAELDLIAPG PLTGVTAHPL APLGPDPVSA IPAEKEDADP LSKSGEETQE QGHDPAEVGA 60
PGEEDQILCD FCLGASRVRA VKSCLTCMVN YCEEHLRPHQ ENSKLHSHQL TEPAKDQDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAATGAGA AGCCTGAGCC AAGGAACAGA CACAGGAGCC AAGTGGCAAG GCAGTTCTGA 60
GCCTTGTCAC TGTGGCTGGC TACTAGCCAA TCTGGAGGAG CCTCGTCCTG TCTGAGTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50188--B302_SPRY

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0019966--F:interleukin-1 binding
GO:0032089--F:NACHT domain binding
GO:0008270--F:zinc ion binding
GO:0043966--P:histone H3 acetylation
GO:0043967--P:histone H4 acetylation
GO:0050718--P:positive regulation of interleukin-1 beta secretion
GO:0045618--P:positive regulation of keratinocyte differentiation
GO:0048386--P:positive regulation of retinoic acid receptor signaling pathway
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0060416--P:response to growth hormone

KEGG

mmu:94092

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004831	Anolis carolinensis	57.68	5.00e-169	587.00
IUUC-Ame-011828	Astyanax mexicanus	41.67	4.00e-119	421.00
IUUC-Bci-013610	Botrytis cinerea	36.11	2.60e-02	30.40
IUUC-Csa-023023	Chlorocebus sabaeus	79.03	0.00e+00	883.00
IUUC-Dre-028527	Danio rerio	46.93	3.00e-119	422.00
IUUC-Dno-029983	Dasypus novemcinctus	79.75	0.00e+00	867.00
IUUC-Dor-030707	Dipodomys ordii	77.60	0.00e+00	852.00
IUUC-Eeu-035116	Erinaceus europaeus	85.34	0.00e+00	642.00
IUUC-Fca-036509	Felis catus	78.96	0.00e+00	870.00
IUUC-Gmo-038676	Gadus morhua	49.16	5.00e-141	494.00
IUUC-Gac-042349	Gasterosteus aculeatus	49.37	5.00e-135	474.00
IUUC-Ggo-044603	Gorilla gorilla	63.04	1.00e-137	483.00
IUUC-Hsa-045796	Homo sapiens	77.17	0.00e+00	853.00
IUUC-Itr-048514	Ictidomys tridecemlineatus	80.25	0.00e+00	887.00
IUUC-Lch-050316	Latimeria chalumnae	51.05	1.00e-133	470.00
IUUC-Loc-052345	Lepisosteus oculatus	49.19	7.00e-143	501.00
IUUC-Laf-054026	Loxodonta africana	74.47	0.00e+00	820.00
IUUC-Meu-055918	Macropus eugenii	71.11	4.00e-69	253.00
IUUC-Mtr-057668	Medicago truncatula	33.33	8.00e-03	33.90
IUUC-Mla-058986	Melampsora laricipopulina	37.78	1.40e-02	34.30
IUUC-Mmr-061463	Microcebus murinus	79.57	0.00e+00	875.00
IUUC-Mdo-062213	Monodelphis domestica	59.63	0.00e+00	632.00
IUUC-Mpu-066313	Mustela putorius furo	80.87	0.00e+00	904.00
IUUC-Nle-069328	Nomascus leucogenys	82.68	2.00e-153	534.00
IUUC-Ont-071376	Oreochromis niloticus	48.30	1.00e-134	473.00
IUUC-Oan-072819	Ornithorhynchus anatinus	70.37	3.00e-118	417.00
IUUC-Ola-086649	Oryzias latipes	59.88	3.00e-64	237.00
IUUC-Oar-089659	Ovis aries	73.93	0.00e+00	849.00
IUUC-Ptr-091335	Pan troglodytes	71.86	0.00e+00	761.00
IUUC-Pan-092676	Papio anubis	78.67	0.00e+00	882.00
IUUC-Psi-093388	Pelodiscus sinensis	56.76	1.00e-178	619.00
IUUC-Pma-094734	Petromyzon marinus	26.27	1.00e-35	144.00
IUUC-Pno-095021	Phaeosphaeria nodorum	34.78	3.50e-01	30.40
IUUC-Pfo-096093	Poecilia formosa	46.77	2.00e-128	452.00
IUUC-Pab-098339	Pongo abelii	76.99	0.00e+00	849.00
IUUC-Rno-105051	Rattus norvegicus	93.01	0.00e+00	1039.00
IUUC-Stu-112388	Solanum tuberosum	30.23	7.00e-02	30.80
IUUC-Sar-113179	Sorex araneus	83.72	4.00e-180	623.00
IUUC-Sre-115138	Sporisorium reilianum	32.43	8.00e-02	29.60
IUUC-Tru-118333	Takifugu rubripes	50.42	2.00e-144	505.00
IUUC-Tsy-119001	Tarsius syrichta	87.19	1.00e-151	530.00
IUUC-Tni-119728	Tetraodon nigroviridis	49.69	4.00e-142	498.00
IUUC-Tae-125126	Triticum aestivum	24.62	2.50e-02	33.50
IUUC-Ttr-128416	Tursiops truncatus	78.76	0.00e+00	698.00
IUUC-Vpa-130818	Vicugna pacos	75.27	0.00e+00	837.00
IUUC-Vvi-130850	Vitis vinifera	26.79	5.00e-03	35.80
IUUC-Xtr-132369	Xenopus tropicalis	52.30	5.00e-138	484.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence