iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007805

Ensembl Protein ID

AAS51736

UniProt Accession

Q75AV4; PFS2_ASHGO

Genbank Protein ID

AAS51736.1

Protein Name

Polyadenylation factor subunit 2

Genbank Nucleotide ID

AE016817

Gene Name

PSF2; ADL184W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_ADL184W	AAS51736	AAS51736

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-35	116.9	208	240
UBD/Beta-Prp	6.20e-73	243.5	77	280

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           v ++++ +  +l+vsGs D+ ik+WD+rtg+ +
   Q: 208  VKSCDWhPKmGLIVSGSKDNLIKLWDPRTGRNV 240
           899****888********************876 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
           + k+vi +++++p+++ l+++ ++g   +w+ ++ ++ + ++ h+++vt +++s+ g++l++g  D+tik+w ++ +   +  ++h++  +++sfs s++k
   Q: 77   KVKHVIPAITWTPEGRRLVVATYSGEFSLWNGSSFNFESIMQAHDSAVTVMQYSHAGDWLISGDADGTIKIWQPNFNMVKVLDRAHTECMRDISFSYSDQK 177
           5688999*******************************************************************9888888888***************** PP
   S: 109  lvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwd 208
           +v+ s+d+++++w+ ++gq  + +lsgh+  v +  +hp+  l+vsGs+D+ ++lWd +tg+ + t  g  ++ v +++f++++ + l+ +s+d+++k++d
   Q: 178  FVTCSDDNVLKIWNFSNGQQER-VLSGHHWDVKSCDWHPKMGLIVSGSKDNLIKLWDPRTGRNVSTILG-LKHTVIKTKFQPTQgNLLAVVSKDKSIKIYD 276
           **********************.*********************************************9.************99799999*********** PP
   S: 209  lqtg 212
           +++ 
   Q: 277  MRQH 280
           *965 PP

Organism

Ashbya gossypii

Functional Description
(View)

Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

Protein Sequence
(Fasta)

MNSANDGSVK KYVSQRRTVD MSSPYDRLYF YKKHAIPLRT IQPESTYTAD IMPPDAYRDH 60
RRVLNIPTKF THLSSNKVKH VIPAITWTPE GRRLVVATYS GEFSLWNGSS FNFESIMQAH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACAGCG CGAATGATGG CTCAGTCAAA AAGTACGTGT CCCAGCGACG TACGGTGGAT 60
ATGAGCTCGC CCTATGATCG GTTGTATTTC TACAAGAAGC ATGCCATTCC CCTGCGGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0000790--C:nuclear chromatin
GO:0007059--P:chromosome segregation
GO:0006379--P:mRNA cleavage
GO:0006378--P:mRNA polyadenylation
GO:0098789--P:pre-mRNA cleavage required for polyadenylation

KEGG

ago:AGOS_ADL184W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001064	Aegilops tauschii	42.98	1.00e-78	285.00
IUUC-Aml-001363	Ailuropoda melanoleuca	41.42	3.00e-79	288.00
IUUC-Atr-003030	Amborella trichopoda	42.12	3.00e-86	310.00
IUUC-Apl-003409	Anas platyrhynchos	41.21	5.00e-79	287.00
IUUC-Aca-004694	Anolis carolinensis	41.42	1.00e-80	292.00
IUUC-Aly-006063	Arabidopsis lyrata	44.23	2.00e-86	311.00
IUUC-Ath-006583	Arabidopsis thaliana	45.67	2.00e-84	304.00
IUUC-Acl-008075	Aspergillus clavatus	43.13	4.00e-85	306.00
IUUC-Afl-008582	Aspergillus flavus	43.21	1.00e-86	311.00
IUUC-Afu-008817	Aspergillus fumigatus	40.74	9.00e-74	268.00
IUUC-Ani-009391	Aspergillus nidulans	39.84	1.00e-75	275.00
IUUC-Ang-009750	Aspergillus niger	45.52	6.00e-73	265.00
IUUC-Aor-010085	Aspergillus oryzae	43.21	2.00e-86	311.00
IUUC-Ate-010397	Aspergillus terreus	42.93	2.00e-86	311.00
IUUC-Ame-010741	Astyanax mexicanus	43.36	4.00e-57	214.00
IUUC-Bgr-012169	Blumeria graminis	45.86	2.00e-91	327.00
IUUC-Bta-013265	Bos taurus	41.42	2.00e-80	292.00
IUUC-Bci-013762	Botrytis cinerea	47.22	3.00e-97	347.00
IUUC-Bdi-014849	Brachypodium distachyon	45.45	9.00e-88	315.00
IUUC-Bol-015325	Brassica oleracea	39.82	4.00e-88	316.00
IUUC-Bra-017064	Brassica rapa	43.23	1.00e-88	318.00
IUUC-Cel-018378	Caenorhabditis elegans	37.10	8.00e-72	263.00
IUUC-Cja-019547	Callithrix jacchus	41.42	1.00e-80	292.00
IUUC-Cfa-020031	Canis familiaris	41.42	1.00e-80	292.00
IUUC-Cpo-021554	Cavia porcellus	43.90	1.00e-79	289.00
IUUC-Cre-022830	Chlamydomonas reinhardtii	32.73	3.00e-47	180.00
IUUC-Csa-023146	Chlorocebus sabaeus	41.42	2.00e-80	292.00
IUUC-Cho-024679	Choloepus hoffmanni	43.73	5.00e-72	264.00
IUUC-Cin-025415	Ciona intestinalis	37.98	2.00e-74	271.00
IUUC-Csv-026003	Ciona savignyi	37.87	7.00e-72	262.00
IUUC-Cgl-026391	Colletotrichum gloeosporioides	46.13	8.00e-96	342.00
IUUC-Cne-026983	Cryptococcus neoformans	39.14	2.00e-73	268.00
IUUC-Cme-027147	Cyanidioschyzon merolae	40.84	8.00e-80	288.00
IUUC-Dre-028545	Danio rerio	40.37	3.00e-78	285.00
IUUC-Dno-029677	Dasypus novemcinctus	41.42	1.00e-80	293.00
IUUC-Dse-031371	Dothistroma septosporum	42.11	4.00e-83	300.00
IUUC-Dme-031663	Drosophila melanogaster	42.25	2.00e-80	291.00
IUUC-Ete-032511	Echinops telfairi	35.09	9.00e-58	217.00
IUUC-Eca-034152	Equus caballus	41.42	1.00e-80	292.00
IUUC-Fca-035820	Felis catus	41.16	2.00e-80	292.00
IUUC-Fox-037958	Fusarium oxysporum	46.69	1.00e-95	342.00
IUUC-Fso-038162	Fusarium solani	46.41	8.00e-95	338.00
IUUC-Gmo-039708	Gadus morhua	41.42	1.00e-79	289.00
IUUC-Ggr-040031	Gaeumannomyces graminis	44.41	1.00e-85	308.00
IUUC-Gga-040963	Gallus gallus	41.42	1.00e-80	292.00
IUUC-Gac-041541	Gasterosteus aculeatus	40.11	2.00e-76	278.00
IUUC-Gma-044352	Glycine max	43.48	6.00e-87	313.00
IUUC-Ggo-045564	Gorilla gorilla	41.42	1.00e-80	292.00
IUUC-Hsa-045833	Homo sapiens	41.42	1.00e-80	292.00
IUUC-Hvu-047848	Hordeum vulgare	45.17	1.00e-62	231.00
IUUC-Itr-048083	Ictidomys tridecemlineatus	41.42	2.00e-80	292.00
IUUC-Kpa-049308	Komagataella pastoris	49.63	8.00e-119	417.00
IUUC-Lch-050525	Latimeria chalumnae	43.66	2.00e-79	288.00
IUUC-Lpe-051364	Leersia perrieri	37.56	1.00e-71	261.00
IUUC-Loc-052696	Lepisosteus oculatus	41.16	2.00e-79	288.00
IUUC-Lma-052951	Leptosphaeria maculans	44.20	4.00e-93	333.00
IUUC-Laf-053653	Loxodonta africana	41.42	3.00e-80	291.00
IUUC-Mcc-055797	Macaca mulatta	41.42	1.00e-80	292.00
IUUC-Meu-056331	Macropus eugenii	46.64	2.00e-66	245.00
IUUC-Mor-057168	Magnaporthe oryzae	44.54	2.00e-92	330.00
IUUC-Mpo-057510	Magnaporthe poae	49.15	3.00e-69	253.00
IUUC-Mtr-058032	Medicago truncatula	42.12	4.00e-87	313.00
IUUC-Mla-058852	Melampsora laricipopulina	40.16	1.00e-77	281.00
IUUC-Mga-059311	Meleagris gallopavo	41.42	2.00e-80	292.00
IUUC-Mvi-060544	Microbotryum violaceum	40.21	5.00e-83	299.00
IUUC-Mmr-061143	Microcebus murinus	41.42	1.00e-80	292.00
IUUC-Mdo-061977	Monodelphis domestica	41.42	2.00e-80	292.00
IUUC-Mmu-063922	Mus musculus	41.42	1.00e-80	292.00
IUUC-Mac-064961	Musa acuminata	40.87	1.00e-91	328.00
IUUC-Mpu-066079	Mustela putorius furo	45.02	3.00e-76	278.00
IUUC-Mlu-067247	Myotis lucifugus	41.42	9.00e-81	293.00
IUUC-Nfi-068255	Neosartorya fischeri	43.66	8.00e-83	298.00
IUUC-Ncr-068909	Neurospora crassa	47.14	1.00e-97	348.00
IUUC-Nle-068994	Nomascus leucogenys	41.42	1.00e-80	292.00
IUUC-Opr-071079	Ochotona princeps	41.16	9.00e-80	290.00
IUUC-Ont-071971	Oreochromis niloticus	40.91	2.00e-79	288.00
IUUC-Oan-073135	Ornithorhynchus anatinus	43.60	3.00e-79	288.00
IUUC-Ocu-073982	Oryctolagus cuniculus	41.42	1.00e-80	292.00
IUUC-Oba-075297	Oryza barthii	38.02	7.00e-75	272.00
IUUC-Obr-076641	Oryza brachyantha	45.45	6.00e-87	312.00
IUUC-Ogl-077539	Oryza glaberrima	40.91	4.00e-65	239.00
IUUC-Ogu-078807	Oryza glumaepatula	38.02	9.00e-75	272.00
IUUC-Oin-079229	Oryza indica	41.24	1.00e-87	315.00
IUUC-Olo-080371	Oryza longistaminata	38.02	7.00e-75	272.00
IUUC-Ome-081149	Oryza meridionalis	37.79	6.00e-74	270.00
IUUC-Oni-082970	Oryza nivara	38.02	8.00e-75	272.00
IUUC-Opu-083415	Oryza punctata	37.56	4.00e-72	263.00
IUUC-Oru-085236	Oryza rufipogon	38.02	1.00e-74	271.00
IUUC-Ola-087421	Oryzias latipes	41.44	8.00e-81	292.00
IUUC-Olu-087821	Ostreococcus lucimarinus	39.06	6.00e-74	268.00
IUUC-Oga-088132	Otolemur garnettii	41.42	1.00e-80	292.00
IUUC-Oar-089513	Ovis aries	41.42	2.00e-80	292.00
IUUC-Ptr-090717	Pan troglodytes	41.42	1.00e-80	292.00
IUUC-Pan-092108	Papio anubis	41.42	1.00e-80	293.00
IUUC-Psi-093892	Pelodiscus sinensis	41.42	2.00e-80	291.00
IUUC-Pma-094561	Petromyzon marinus	40.91	9.00e-80	290.00
IUUC-Pno-094943	Phaeosphaeria nodorum	45.50	4.00e-94	336.00
IUUC-Ppa-095359	Physcomitrella patens	45.41	4.00e-92	330.00
IUUC-Pfo-096516	Poecilia formosa	40.79	5.00e-78	283.00
IUUC-Pab-097759	Pongo abelii	41.42	2.00e-80	292.00
IUUC-Pop-099553	Populus trichocarpa	41.04	4.00e-88	317.00
IUUC-Ppe-101957	Prunus persica	44.41	4.00e-90	323.00
IUUC-Pva-102918	Pteropus vampyrus	41.42	1.00e-80	292.00
IUUC-Pgr-103594	Puccinia graminis	40.11	8.00e-80	289.00
IUUC-Ptt-103879	Puccinia triticina	44.10	2.00e-72	265.00
IUUC-Pte-104419	Pyrenophora teres	43.87	8.00e-93	332.00
IUUC-Pyt-104718	Pyrenophora triticirepentis	44.44	9.00e-93	332.00
IUUC-Rno-105838	Rattus norvegicus	41.42	2.00e-80	292.00
IUUC-Sce-106331	Saccharomyces cerevisiae	65.41	0.00e+00	641.00
IUUC-Sha-107435	Sarcophilus harrisii	41.25	1.00e-80	293.00
IUUC-Sja-107796	Schizosaccharomyces japonicus	41.98	2.00e-87	314.00
IUUC-Spo-108163	Schizosaccharomyces pombe	39.11	2.00e-84	304.00
IUUC-Smo-109602	Selaginella moellendorffii	44.90	1.00e-91	327.00
IUUC-Sit-109729	Setaria italica	44.08	4.00e-84	303.00
IUUC-Sly-111679	Solanum lycopersicum	44.69	1.00e-89	322.00
IUUC-Sar-113157	Sorex araneus	41.42	1.00e-80	293.00
IUUC-Sbi-114853	Sorghum bicolor	44.08	3.00e-83	300.00
IUUC-Sre-115085	Sporisorium reilianum	37.05	5.00e-72	263.00
IUUC-Ssc-116286	Sus scrofa	41.32	4.00e-79	288.00
IUUC-Tgu-117219	Taeniopygia guttata	41.42	2.00e-80	292.00
IUUC-Tru-117550	Takifugu rubripes	37.04	1.00e-80	291.00
IUUC-Tsy-119294	Tarsius syrichta	41.42	1.00e-80	293.00
IUUC-Tni-120561	Tetraodon nigroviridis	41.16	2.00e-79	288.00
IUUC-Tca-121347	Theobroma cacao	40.09	2.00e-89	321.00
IUUC-Tre-122018	Trichoderma reesei	47.22	4.00e-95	340.00
IUUC-Tvi-122413	Trichoderma virens	46.94	2.00e-94	337.00
IUUC-Tae-123191	Triticum aestivum	44.63	3.00e-86	310.00
IUUC-Tme-127077	Tuber melanosporum	52.92	5.00e-106	375.00
IUUC-Tbe-127744	Tupaia belangeri	32.33	8.00e-42	164.00
IUUC-Ttr-128777	Tursiops truncatus	36.63	3.00e-57	215.00
IUUC-Uma-129568	Ustilago maydis	36.56	2.00e-67	247.00
IUUC-Vda-129834	Verticillium dahliae	44.20	2.00e-92	330.00
IUUC-Vpa-130579	Vicugna pacos	23.03	2.00e-20	91.30
IUUC-Vvi-131360	Vitis vinifera	44.41	3.00e-89	320.00
IUUC-Xtr-132630	Xenopus tropicalis	41.33	5.00e-77	281.00
IUUC-Xma-133665	Xiphophorus maculatus	41.42	4.00e-80	290.00
IUUC-Yli-134556	Yarrowia lipolytica	41.16	2.00e-99	353.00
IUUC-Zma-135787	Zea mays	40.63	6.00e-86	309.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence