iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062478

UUCD1 version

UUC-MoD-00852

Ensembl Protein ID

ENSMODP00000037998.2

UniProt Accession

F7GG23; F7GG23_MONDO

Protein Name

Uncharacterized protein

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013073.3	ENSMODT00000039600.2	ENSMODP00000037998.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	85.42	0.00e+00	1936.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAENVVEPGP PSAKRPKLAS PALSVAASDG TDFGSLFDLE HDLPDELINS SELGLSNGSD 60
IGQLQTSLSM VQDAASKHKQ LSELLRAGSS PNLNMGVGGP GQGMATQAQQ NSPGMGILNS 120

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Nucleotide Sequence
(Fasta)

GCCGTCGCTT CTGCTGCTGC TTGCTGCTGC CACTGCTGCT GCCGCCACCG CCACCGCCGT 60
CGCCGCTGCT GCTGCTGCCG CCGCCGGCGC TCGCCTGGGA GCGGGAGGAG CAGGAGCAGG 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR011990--TPR-like_helical_dom
IPR001781--Znf_LIM
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

KEGG

mdo:100028102

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002027	Ailuropoda melanoleuca	84.79	0.00e+00	1781.00
IUUC-Aca-005040	Anolis carolinensis	80.50	0.00e+00	1860.00
IUUC-Ame-011395	Astyanax mexicanus	85.01	0.00e+00	1477.00
IUUC-Bta-012649	Bos taurus	84.71	0.00e+00	1872.00
IUUC-Cel-018691	Caenorhabditis elegans	49.36	0.00e+00	844.00
IUUC-Cja-019649	Callithrix jacchus	83.65	0.00e+00	1904.00
IUUC-Cfa-020764	Canis familiaris	90.74	0.00e+00	1703.00
IUUC-Cpo-022345	Cavia porcellus	82.75	0.00e+00	1904.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	34.59	9.00e-65	242.00
IUUC-Csa-023866	Chlorocebus sabaeus	87.08	0.00e+00	1781.00
IUUC-Cho-024951	Choloepus hoffmanni	93.32	0.00e+00	1189.00
IUUC-Dre-028500	Danio rerio	72.79	0.00e+00	1474.00
IUUC-Ete-032979	Echinops telfairi	81.58	0.00e+00	1645.00
IUUC-Eca-034048	Equus caballus	87.48	0.00e+00	1757.00
IUUC-Fca-035891	Felis catus	88.12	0.00e+00	1773.00
IUUC-Fal-037585	Ficedula albicollis	84.64	0.00e+00	1905.00
IUUC-Gmo-039348	Gadus morhua	87.74	0.00e+00	1454.00
IUUC-Gga-040916	Gallus gallus	87.61	0.00e+00	1847.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.60	0.00e+00	1419.00
IUUC-Ggo-045189	Gorilla gorilla	84.71	0.00e+00	1862.00
IUUC-Hsa-046884	Homo sapiens	84.51	0.00e+00	1854.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	88.17	0.00e+00	1730.00
IUUC-Laf-054423	Loxodonta africana	86.36	0.00e+00	1861.00
IUUC-Mcc-054847	Macaca mulatta	84.71	0.00e+00	1870.00
IUUC-Meu-056217	Macropus eugenii	87.85	0.00e+00	2039.00
IUUC-Mga-059250	Meleagris gallopavo	86.07	0.00e+00	1823.00
IUUC-Mmr-061496	Microcebus murinus	87.32	0.00e+00	1783.00
IUUC-Mmu-063456	Mus musculus	85.81	0.00e+00	1767.00
IUUC-Mac-065060	Musa acuminata	33.11	2.00e-100	361.00
IUUC-Mpu-065963	Mustela putorius furo	84.61	0.00e+00	1766.00
IUUC-Mlu-067185	Myotis lucifugus	87.34	0.00e+00	1756.00
IUUC-Nle-069907	Nomascus leucogenys	87.98	0.00e+00	1757.00
IUUC-Opr-070324	Ochotona princeps	74.76	0.00e+00	1019.00
IUUC-Ont-072211	Oreochromis niloticus	79.27	0.00e+00	1476.00
IUUC-Oan-073723	Ornithorhynchus anatinus	90.79	0.00e+00	1897.00
IUUC-Ocu-074707	Oryctolagus cuniculus	86.84	0.00e+00	1749.00
IUUC-Osa-085860	Oryza sativa	41.61	8.00e-62	233.00
IUUC-Olu-087701	Ostreococcus lucimarinus	34.95	7.00e-62	232.00
IUUC-Oga-088700	Otolemur garnettii	85.18	0.00e+00	1877.00
IUUC-Oar-089787	Ovis aries	87.99	0.00e+00	1806.00
IUUC-Ptr-091620	Pan troglodytes	84.17	0.00e+00	1856.00
IUUC-Pan-092166	Papio anubis	84.17	0.00e+00	1887.00
IUUC-Psi-093992	Pelodiscus sinensis	87.69	0.00e+00	1909.00
IUUC-Ppa-095569	Physcomitrella patens	37.97	1.00e-70	262.00
IUUC-Pfo-097342	Poecilia formosa	75.29	0.00e+00	1393.00
IUUC-Pab-098235	Pongo abelii	86.79	0.00e+00	1778.00
IUUC-Pca-100780	Procavia capensis	85.64	0.00e+00	1410.00
IUUC-Pva-103071	Pteropus vampyrus	87.64	0.00e+00	1853.00
IUUC-Sha-106736	Sarcophilus harrisii	96.91	0.00e+00	1722.00
IUUC-Sit-110128	Setaria italica	31.78	2.00e-94	341.00
IUUC-Sar-113162	Sorex araneus	83.76	0.00e+00	751.00
IUUC-Ssc-116077	Sus scrofa	87.00	0.00e+00	1803.00
IUUC-Tgu-116872	Taeniopygia guttata	83.39	0.00e+00	1897.00
IUUC-Tru-118047	Takifugu rubripes	67.95	0.00e+00	1842.00
IUUC-Tsy-119451	Tarsius syrichta	80.52	0.00e+00	1251.00
IUUC-Tur-126284	Triticum urartu	37.40	1.00e-67	252.00
IUUC-Tbe-127772	Tupaia belangeri	77.46	0.00e+00	1176.00
IUUC-Ttr-128325	Tursiops truncatus	92.51	0.00e+00	1402.00
IUUC-Vpa-130766	Vicugna pacos	92.52	0.00e+00	1167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence