iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035797

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02128673

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000009004.3	ENSFCAT00000009008.3	ENSFCAP00000008348.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	90.84	0.00e+00	1961.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	28.37	3.00e-41	165.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

VRRFKRKHLT AIDCQHLARS HLAVTQPFGQ RWTNRDPNHG LYPRPRTKRG TRGQGCQRYG 60
TEFLLAGQQR RTNDMAKSNS VGQDTSKDSE GEMIFAAESN CALPREGDGE ARLGSSGSAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGACGGT TTAAACGGAA GCATCTTACA GCCATCGACT GCCAACATTT GGCTCGGAGT 60
CACTTGGCTG TGACCCAGCC CTTCGGTCAA AGATGGACCA ACAGAGACCC GAACCACGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	25.47	5.00e-04	40.80
IUUC-Aml-001396	Ailuropoda melanoleuca	95.52	0.00e+00	2019.00
IUUC-Atr-002826	Amborella trichopoda	39.39	2.00e-04	42.40
IUUC-Apl-003317	Anas platyrhynchos	48.31	0.00e+00	926.00
IUUC-Aca-004498	Anolis carolinensis	50.30	0.00e+00	942.00
IUUC-Aly-006174	Arabidopsis lyrata	34.43	5.00e-04	36.60
IUUC-Ath-007293	Arabidopsis thaliana	35.21	1.00e-03	39.70
IUUC-Ani-009226	Aspergillus nidulans	30.33	4.00e-05	43.90
IUUC-Ate-010526	Aspergillus terreus	40.82	5.00e-03	37.00
IUUC-Ame-011808	Astyanax mexicanus	58.82	2.00e-134	471.00
IUUC-Bta-013250	Bos taurus	90.55	0.00e+00	1922.00
IUUC-Bol-015348	Brassica oleracea	35.21	6.00e-04	40.00
IUUC-Cja-019638	Callithrix jacchus	91.70	0.00e+00	1988.00
IUUC-Cfa-020195	Canis familiaris	96.00	0.00e+00	1919.00
IUUC-Cpo-022269	Cavia porcellus	86.74	0.00e+00	1808.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	4.00e-08	53.90
IUUC-Csa-024060	Chlorocebus sabaeus	92.81	0.00e+00	1766.00
IUUC-Cho-025003	Choloepus hoffmanni	90.66	0.00e+00	720.00
IUUC-Cin-025694	Ciona intestinalis	27.43	9.00e-29	120.00
IUUC-Dre-028083	Danio rerio	49.83	0.00e+00	843.00
IUUC-Dno-029203	Dasypus novemcinctus	88.37	0.00e+00	1783.00
IUUC-Dor-030477	Dipodomys ordii	97.46	0.00e+00	794.00
IUUC-Ete-032861	Echinops telfairi	88.07	0.00e+00	1860.00
IUUC-Eca-033205	Equus caballus	94.94	0.00e+00	2046.00
IUUC-Eeu-034784	Erinaceus europaeus	86.12	0.00e+00	1195.00
IUUC-Gmo-038855	Gadus morhua	46.55	1.00e-122	434.00
IUUC-Gga-040326	Gallus gallus	49.76	0.00e+00	974.00
IUUC-Gac-042240	Gasterosteus aculeatus	46.61	0.00e+00	732.00
IUUC-Ggo-045050	Gorilla gorilla	88.43	0.00e+00	1819.00
IUUC-Hsa-046650	Homo sapiens	91.03	0.00e+00	1911.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	97.17	0.00e+00	779.00
IUUC-Lch-050231	Latimeria chalumnae	49.03	2.00e-156	546.00
IUUC-Loc-051884	Lepisosteus oculatus	49.91	0.00e+00	981.00
IUUC-Lma-053267	Leptosphaeria maculans	25.45	3.00e-03	37.70
IUUC-Laf-053843	Loxodonta africana	91.70	0.00e+00	1939.00
IUUC-Mcc-055570	Macaca mulatta	91.89	0.00e+00	1939.00
IUUC-Meu-056798	Macropus eugenii	66.67	3.00e-149	522.00
IUUC-Mtr-057915	Medicago truncatula	36.76	4.00e-04	40.80
IUUC-Mga-059648	Meleagris gallopavo	50.82	0.00e+00	929.00
IUUC-Mmr-060757	Microcebus murinus	89.59	0.00e+00	1853.00
IUUC-Mdo-061913	Monodelphis domestica	69.61	0.00e+00	1375.00
IUUC-Mmu-064337	Mus musculus	88.84	0.00e+00	1920.00
IUUC-Mpu-066483	Mustela putorius furo	92.94	0.00e+00	1999.00
IUUC-Mlu-068204	Myotis lucifugus	87.93	0.00e+00	1867.00
IUUC-Ncr-068735	Neurospora crassa	34.85	2.80e-02	34.70
IUUC-Nle-070053	Nomascus leucogenys	91.79	0.00e+00	1884.00
IUUC-Opr-070588	Ochotona princeps	86.26	0.00e+00	1801.00
IUUC-Ont-072655	Oreochromis niloticus	47.45	0.00e+00	759.00
IUUC-Oan-073351	Ornithorhynchus anatinus	61.98	0.00e+00	1297.00
IUUC-Ocu-074465	Oryctolagus cuniculus	90.48	0.00e+00	1849.00
IUUC-Oin-079176	Oryza indica	23.78	3.00e-07	50.10
IUUC-Olu-087831	Ostreococcus lucimarinus	31.16	2.00e-63	238.00
IUUC-Oga-089088	Otolemur garnettii	88.65	0.00e+00	1837.00
IUUC-Oar-089870	Ovis aries	89.89	0.00e+00	1878.00
IUUC-Ptr-090957	Pan troglodytes	91.80	0.00e+00	1887.00
IUUC-Pan-092632	Papio anubis	91.89	0.00e+00	1887.00
IUUC-Psi-093035	Pelodiscus sinensis	55.08	0.00e+00	1124.00
IUUC-Pno-094870	Phaeosphaeria nodorum	24.20	5.00e-04	40.40
IUUC-Ppa-095660	Physcomitrella patens	40.54	2.00e-04	42.40
IUUC-Pfo-096902	Poecilia formosa	44.87	0.00e+00	685.00
IUUC-Pab-098206	Pongo abelii	91.94	0.00e+00	1778.00
IUUC-Pop-098801	Populus trichocarpa	37.68	2.00e-04	41.60
IUUC-Pca-100238	Procavia capensis	85.97	0.00e+00	1801.00
IUUC-Ppe-101748	Prunus persica	36.62	3.00e-03	38.10
IUUC-Pva-103182	Pteropus vampyrus	90.94	0.00e+00	1890.00
IUUC-Pte-104033	Pyrenophora teres	23.53	2.00e-03	38.10
IUUC-Pyt-104599	Pyrenophora triticirepentis	23.21	1.00e-03	38.50
IUUC-Rno-105141	Rattus norvegicus	88.36	0.00e+00	1915.00
IUUC-Sce-106341	Saccharomyces cerevisiae	25.76	3.00e-03	37.40
IUUC-Sha-106827	Sarcophilus harrisii	67.27	0.00e+00	1426.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	28.25	2.00e-43	171.00
IUUC-Spo-108147	Schizosaccharomyces pombe	28.88	2.00e-44	174.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	25.00	1.00e-03	38.50
IUUC-Sly-111170	Solanum lycopersicum	35.94	2.50e-02	33.90
IUUC-Sre-115025	Sporisorium reilianum	33.02	4.00e-38	154.00
IUUC-Ssc-116188	Sus scrofa	95.85	0.00e+00	1280.00
IUUC-Tgu-116612	Taeniopygia guttata	56.64	4.00e-154	537.00
IUUC-Tsy-119560	Tarsius syrichta	83.06	2.00e-117	416.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.92	0.00e+00	710.00
IUUC-Tca-121338	Theobroma cacao	30.91	6.00e-03	37.00
IUUC-Tre-122089	Trichoderma reesei	40.74	2.00e-04	41.20
IUUC-Tme-127009	Tuber melanosporum	26.85	2.00e-03	38.10
IUUC-Tbe-127431	Tupaia belangeri	90.11	0.00e+00	1638.00
IUUC-Ttr-128744	Tursiops truncatus	90.37	0.00e+00	1883.00
IUUC-Uma-129536	Ustilago maydis	34.06	2.00e-40	161.00
IUUC-Vpa-130123	Vicugna pacos	81.82	8.00e-112	397.00
IUUC-Vvi-131025	Vitis vinifera	35.21	1.00e-03	38.90
IUUC-Xtr-132902	Xenopus tropicalis	58.70	0.00e+00	1014.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence