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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063334
UUCD1 version UUC-MuM-00982
Ensembl Protein ID ENSMUSP00000022666.7
UniProt Accession Q9JI74; Q505E9; KLHL1_MOUSE
Genbank Protein ID AAF81717.1; CAO77960.1; CAO77960.1; CAO77960.1; CAO77960.1; AAH94584.1
Protein Name Kelch-like protein 1
Genbank Nucleotide ID AF252281; CT025590; AC131920; AC131989; AC154580; BC094584
Gene Name Klhl1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022076.9 ENSMUST00000022666.7 ENSMUSP00000022666.7
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
iRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 2.20e-18 67.5 215 282
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box 8.10e-07 28.4 314 340
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 215  CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 282
           9************************************9.**************************9986 PP
   

   E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box
   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 314  PSNCLGIRAFADAQGCIELMKVAHSYT 340
           89***********************95 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MSGSGRKDFD VKHILRLRWK LFSHPSPASS SPAGGSCLQQ DSGGGSFEHW GPSQSRLLKN 60
QEKGSVSAFW KKPSSSSSSS SSSSSSASSS PFNPLNGTLL PVATRLQQGA PGQGTQQPAR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063334|E3,BTB_3-box|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGAGAGAAAA ATCATACTGT GAGGACCTTG ACAGCTTTCC TGGGCGGGCT TTTCTTTGGC 60
TGCTCTATGT TTTTTCCCGG GATATTTATT TTTCTCCTTT ACAAACTGAC TATATAAAAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063334|E3,BTB_3-box|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0007626--P:locomotory behavior
GO:0016567--P:protein ubiquitination
KEGG mmu:93688
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001478 Ailuropoda melanoleuca 95.61 0.00e+00 1334.00
IUUC-Apl-003408 Anas platyrhynchos 95.55 0.00e+00 1108.00
IUUC-Aca-004384 Anolis carolinensis 84.77 0.00e+00 1226.00
IUUC-Bta-012684 Bos taurus 97.94 0.00e+00 1132.00
IUUC-Bci-013875 Botrytis cinerea 28.24 3.00e-18 85.90
IUUC-Cja-019103 Callithrix jacchus 95.34 0.00e+00 1329.00
IUUC-Cfa-020670 Canis familiaris 97.24 0.00e+00 1189.00
IUUC-Cpo-021951 Cavia porcellus 98.12 0.00e+00 1134.00
IUUC-Csa-023607 Chlorocebus sabaeus 98.11 0.00e+00 1130.00
IUUC-Cho-024648 Choloepus hoffmanni 84.70 0.00e+00 1114.00
IUUC-Dno-029854 Dasypus novemcinctus 93.21 0.00e+00 1289.00
IUUC-Dor-030497 Dipodomys ordii 78.39 0.00e+00 970.00
IUUC-Eca-033525 Equus caballus 94.94 0.00e+00 1358.00
IUUC-Fca-035490 Felis catus 98.11 0.00e+00 1129.00
IUUC-Fal-037099 Ficedula albicollis 96.97 0.00e+00 1101.00
IUUC-Fox-038050 Fusarium oxysporum 28.74 1.00e-06 47.00
IUUC-Gga-041081 Gallus gallus 86.42 0.00e+00 1195.00
IUUC-Gma-043533 Glycine max 32.64 1.00e-38 154.00
IUUC-Ggo-044717 Gorilla gorilla 95.21 0.00e+00 1326.00
IUUC-Hsa-045726 Homo sapiens 95.21 0.00e+00 1326.00
IUUC-Itr-048921 Ictidomys tridecemlineatus 95.61 0.00e+00 1333.00
IUUC-Loc-052321 Lepisosteus oculatus 75.37 0.00e+00 1079.00
IUUC-Laf-054378 Loxodonta africana 94.94 0.00e+00 1322.00
IUUC-Mcc-054985 Macaca mulatta 95.47 0.00e+00 1327.00
IUUC-Mmr-061255 Microcebus murinus 85.22 0.00e+00 1160.00
IUUC-Mdo-062369 Monodelphis domestica 92.28 0.00e+00 1319.00
IUUC-Nle-069856 Nomascus leucogenys 95.34 0.00e+00 1328.00
IUUC-Ocu-074469 Oryctolagus cuniculus 94.41 0.00e+00 1316.00
IUUC-Obr-076712 Oryza brachyantha 29.17 2.00e-33 137.00
IUUC-Ogl-077595 Oryza glaberrima 30.80 3.00e-35 143.00
IUUC-Oin-080100 Oryza indica 29.51 2.00e-34 140.00
IUUC-Olu-087696 Ostreococcus lucimarinus 36.36 6.00e-33 134.00
IUUC-Oga-088528 Otolemur garnettii 96.60 0.00e+00 1181.00
IUUC-Oar-089603 Ovis aries 97.77 0.00e+00 1127.00
IUUC-Ptr-090657 Pan troglodytes 94.81 0.00e+00 1322.00
IUUC-Psi-092962 Pelodiscus sinensis 95.71 0.00e+00 1112.00
IUUC-Pab-097812 Pongo abelii 94.67 0.00e+00 1296.00
IUUC-Pva-103042 Pteropus vampyrus 94.55 0.00e+00 1322.00
IUUC-Sbi-114612 Sorghum bicolor 28.81 8.00e-35 142.00
IUUC-Ssc-115880 Sus scrofa 97.94 0.00e+00 1131.00
IUUC-Tgu-116624 Taeniopygia guttata 94.79 0.00e+00 981.00
IUUC-Tru-117780 Takifugu rubripes 66.67 0.00e+00 920.00
IUUC-Tsy-119339 Tarsius syrichta 87.48 0.00e+00 1187.00
IUUC-Tbe-127398 Tupaia belangeri 99.38 0.00e+00 678.00
IUUC-Ttr-129024 Tursiops truncatus 94.41 0.00e+00 1362.00
IUUC-Vpa-130515 Vicugna pacos 97.77 0.00e+00 1130.00
Created Date 25-Jun-2017

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