iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000016030.4	ENSCAFT00000025429.4	ENSCAFP00000023612.3
ENSCAFG00000016030.4	ENSCAFT00000043977.1	ENSCAFP00000042711.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	8.60e-13	48.8	24	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+++ +++ +f+ahk+vLaa+Ss+F+  f +++ +  +  +  ++k +++e+f  +l+F+Y gk+
   Q: 24   CDCCIAIDDIYFQAHKAVLAACSSYFRMFFmNHQHSTAQ-LNLSNMK-ISAECFDLILQFMYLGKI 87
           8*************************9999333333333.5555666.****************97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAKPSHSSYV LQQLNNQREW GFLCDCCIAI DDIYFQAHKA VLAACSSYFR MFFMNHQHST 60
AQLNLSNMKI SAECFDLILQ FMYLGKIMTA PSSFEQFKVA MNYLQLYNVP DCLEDIQDAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGCCTCCGC CCGCCTTTCC CGTGGCCGGT TTGCCTTAAA CTCCCTAAAA CCTCCGCAGC 60
CCCGGTTCCT GCCGCGGCCG GTGAGTATCT GCCAGTTGTG GGGCTATTTG CGCAACTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR000877--Prot_inh_BBI
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0016604--C:nuclear body
GO:0031965--C:nuclear membrane
GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0006338--P:chromatin remodeling
GO:0042789--P:mRNA transcription from RNA polymerase II promoter
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032825--P:positive regulation of natural killer cell differentiation
GO:2000176--P:positive regulation of pro-T cell differentiation
GO:0002711--P:positive regulation of T cell mediated immunity
GO:0051260--P:protein homooligomerization
GO:0033077--P:T cell differentiation in thymus
GO:0048538--P:thymus development
GO:0019985--P:translesion synthesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001844	Ailuropoda melanoleuca	97.48	0.00e+00	1356.00
IUUC-Apl-003725	Anas platyrhynchos	81.86	0.00e+00	1133.00
IUUC-Aca-004672	Anolis carolinensis	71.61	0.00e+00	954.00
IUUC-Ame-011859	Astyanax mexicanus	48.77	2.00e-179	622.00
IUUC-Bta-013323	Bos taurus	97.48	0.00e+00	1402.00
IUUC-Cja-018727	Callithrix jacchus	97.05	0.00e+00	1350.00
IUUC-Cpo-022434	Cavia porcellus	96.21	0.00e+00	1387.00
IUUC-Csa-023909	Chlorocebus sabaeus	95.41	0.00e+00	1159.00
IUUC-Cho-024288	Choloepus hoffmanni	94.92	0.00e+00	934.00
IUUC-Dre-027623	Danio rerio	48.56	2.00e-180	625.00
IUUC-Dno-029224	Dasypus novemcinctus	96.91	0.00e+00	1394.00
IUUC-Ete-032672	Echinops telfairi	90.75	0.00e+00	980.00
IUUC-Eca-034361	Equus caballus	96.84	0.00e+00	1179.00
IUUC-Eeu-035254	Erinaceus europaeus	91.88	9.00e-158	550.00
IUUC-Fca-036217	Felis catus	97.34	0.00e+00	1395.00
IUUC-Fal-037026	Ficedula albicollis	77.69	0.00e+00	955.00
IUUC-Gga-040550	Gallus gallus	76.50	2.00e-143	501.00
IUUC-Gac-041379	Gasterosteus aculeatus	46.48	3.00e-171	595.00
IUUC-Ggo-044852	Gorilla gorilla	97.19	0.00e+00	1397.00
IUUC-Hsa-046418	Homo sapiens	97.05	0.00e+00	1395.00
IUUC-Itr-048065	Ictidomys tridecemlineatus	95.93	0.00e+00	1377.00
IUUC-Lch-050025	Latimeria chalumnae	56.06	0.00e+00	786.00
IUUC-Loc-052590	Lepisosteus oculatus	49.67	0.00e+00	653.00
IUUC-Laf-054526	Loxodonta africana	96.21	0.00e+00	1366.00
IUUC-Mcc-055796	Macaca mulatta	95.93	0.00e+00	1332.00
IUUC-Mga-059889	Meleagris gallopavo	81.16	0.00e+00	1145.00
IUUC-Mmr-061304	Microcebus murinus	96.63	0.00e+00	1347.00
IUUC-Mdo-062964	Monodelphis domestica	88.64	0.00e+00	1273.00
IUUC-Mmu-064268	Mus musculus	93.69	0.00e+00	1345.00
IUUC-Mpu-065817	Mustela putorius furo	97.15	0.00e+00	1181.00
IUUC-Mlu-068225	Myotis lucifugus	96.35	0.00e+00	1365.00
IUUC-Nle-069390	Nomascus leucogenys	97.05	0.00e+00	1395.00
IUUC-Opr-070274	Ochotona princeps	94.39	0.00e+00	1327.00
IUUC-Ont-072145	Oreochromis niloticus	46.18	3.00e-170	591.00
IUUC-Oan-073144	Ornithorhynchus anatinus	84.60	0.00e+00	1020.00
IUUC-Ocu-074835	Oryctolagus cuniculus	88.50	0.00e+00	1237.00
IUUC-Ola-087520	Oryzias latipes	46.13	6.00e-169	587.00
IUUC-Oga-088605	Otolemur garnettii	96.35	0.00e+00	1378.00
IUUC-Oar-089788	Ovis aries	97.48	0.00e+00	1402.00
IUUC-Ptr-091274	Pan troglodytes	97.05	0.00e+00	1395.00
IUUC-Psi-093560	Pelodiscus sinensis	79.35	0.00e+00	1007.00
IUUC-Pfo-097221	Poecilia formosa	61.54	8.00e-108	384.00
IUUC-Pab-097799	Pongo abelii	96.84	0.00e+00	1225.00
IUUC-Pva-102769	Pteropus vampyrus	96.49	0.00e+00	1348.00
IUUC-Rno-105959	Rattus norvegicus	91.46	0.00e+00	1167.00
IUUC-Sha-106613	Sarcophilus harrisii	88.78	0.00e+00	1266.00
IUUC-Sar-112951	Sorex araneus	86.05	0.00e+00	1080.00
IUUC-Ssc-115673	Sus scrofa	97.34	0.00e+00	1352.00
IUUC-Tgu-116806	Taeniopygia guttata	79.78	0.00e+00	1102.00
IUUC-Tru-117544	Takifugu rubripes	43.65	3.00e-132	465.00
IUUC-Tsy-119233	Tarsius syrichta	90.32	0.00e+00	1231.00
IUUC-Tni-120273	Tetraodon nigroviridis	57.05	6.00e-101	361.00
IUUC-Tbe-128020	Tupaia belangeri	95.62	0.00e+00	1177.00
IUUC-Ttr-128357	Tursiops truncatus	97.19	0.00e+00	1342.00
IUUC-Vpa-130487	Vicugna pacos	97.34	0.00e+00	1398.00
IUUC-Xtr-132415	Xenopus tropicalis	59.05	0.00e+00	795.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence