iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062977

UUCD1 version

UUC-MoD-01014

Ensembl Protein ID

ENSMODP00000002849.3

UniProt Accession

F7GLX9; F7GLX9_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000002334.3	ENSMODT00000002905.3	ENSMODP00000002849.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-21	75.9	56	123
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.20e-08	34.2	157	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e++ah++vLaa+S++F+a+f++e++es+  +++ ik+v+   +r l++++Yt +++ +e
   Q: 56   CDVTIVADDMEISAHRVVLAACSPYFHAMFTGEMSESR-AKRIRIKEVDGWTLRMLIDYVYTAEIQVTE 123
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkhF 31
           Nclgi++fAd++ c++L  +a+ ++++hF
   Q: 157  NCLGIRAFADMHACTELLNKANIYAEQHF 185
           ***************************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEMMLLPPVC PKQNSQKPPD TKDDNTEKHC PVTVNPWHMK KAFKVMNELR SQNLLCDVTI 60
VADDMEISAH RVVLAACSPY FHAMFTGEMS ESRAKRIRIK EVDGWTLRML IDYVYTAEIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCA AAAGAAAAGA GTTGGAGGTC AATGAACTCT AAGGTCCCTT CCACCTCCGA 60
TCCTATGAGT CTATGATCTT TGGACCCACT AGATCCTGCT TTGCTGCTAG CAGATGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0003779--F:actin binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mdo:100021973

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	94.56	0.00e+00	1129.00
IUUC-Apl-003260	Anas platyrhynchos	92.47	0.00e+00	1093.00
IUUC-Aca-005143	Anolis carolinensis	88.22	0.00e+00	1102.00
IUUC-Cja-018942	Callithrix jacchus	95.38	0.00e+00	1129.00
IUUC-Cfa-020886	Canis familiaris	95.38	0.00e+00	1132.00
IUUC-Cpo-022543	Cavia porcellus	94.77	0.00e+00	1138.00
IUUC-Csa-023088	Chlorocebus sabaeus	95.11	0.00e+00	1142.00
IUUC-Dre-028082	Danio rerio	81.19	0.00e+00	975.00
IUUC-Dno-029873	Dasypus novemcinctus	93.03	0.00e+00	1107.00
IUUC-Dor-030460	Dipodomys ordii	76.54	0.00e+00	830.00
IUUC-Dse-031229	Dothistroma septosporum	37.14	6.00e-08	50.80
IUUC-Dme-032172	Drosophila melanogaster	62.25	0.00e+00	672.00
IUUC-Eca-033798	Equus caballus	95.21	0.00e+00	1130.00
IUUC-Eeu-034824	Erinaceus europaeus	87.85	0.00e+00	942.00
IUUC-Fca-036455	Felis catus	95.38	0.00e+00	1132.00
IUUC-Fal-037293	Ficedula albicollis	92.79	0.00e+00	1040.00
IUUC-Gmo-038811	Gadus morhua	78.67	0.00e+00	875.00
IUUC-Gga-040805	Gallus gallus	92.29	0.00e+00	1090.00
IUUC-Gac-041979	Gasterosteus aculeatus	80.77	0.00e+00	876.00
IUUC-Ggo-044620	Gorilla gorilla	89.98	0.00e+00	1071.00
IUUC-Hsa-046265	Homo sapiens	94.94	0.00e+00	1141.00
IUUC-Lch-049939	Latimeria chalumnae	83.42	0.00e+00	970.00
IUUC-Loc-052780	Lepisosteus oculatus	86.10	0.00e+00	1033.00
IUUC-Laf-053800	Loxodonta africana	95.38	0.00e+00	1134.00
IUUC-Mcc-055732	Macaca mulatta	94.68	0.00e+00	1119.00
IUUC-Meu-056011	Macropus eugenii	91.74	0.00e+00	1072.00
IUUC-Mmr-061067	Microcebus murinus	93.23	0.00e+00	1112.00
IUUC-Mmu-064035	Mus musculus	93.85	0.00e+00	1116.00
IUUC-Mpu-066726	Mustela putorius furo	95.55	0.00e+00	1133.00
IUUC-Mlu-067020	Myotis lucifugus	94.74	0.00e+00	1131.00
IUUC-Nle-069456	Nomascus leucogenys	95.55	0.00e+00	1133.00
IUUC-Opr-071130	Ochotona princeps	86.64	0.00e+00	995.00
IUUC-Ont-072219	Oreochromis niloticus	82.34	0.00e+00	927.00
IUUC-Oan-073699	Ornithorhynchus anatinus	95.67	0.00e+00	967.00
IUUC-Ocu-074045	Oryctolagus cuniculus	94.27	0.00e+00	1131.00
IUUC-Oga-088494	Otolemur garnettii	95.03	0.00e+00	1127.00
IUUC-Oar-089645	Ovis aries	94.69	0.00e+00	1123.00
IUUC-Ptr-091063	Pan troglodytes	95.41	0.00e+00	1139.00
IUUC-Pan-092273	Papio anubis	94.29	0.00e+00	929.00
IUUC-Psi-093946	Pelodiscus sinensis	91.64	0.00e+00	1102.00
IUUC-Pma-094177	Petromyzon marinus	74.31	0.00e+00	795.00
IUUC-Pfo-096817	Poecilia formosa	81.29	0.00e+00	940.00
IUUC-Pab-097768	Pongo abelii	94.94	0.00e+00	1139.00
IUUC-Pca-100607	Procavia capensis	78.36	0.00e+00	808.00
IUUC-Pva-102218	Pteropus vampyrus	88.70	0.00e+00	1050.00
IUUC-Rno-105250	Rattus norvegicus	94.10	0.00e+00	1129.00
IUUC-Sar-113249	Sorex araneus	94.61	0.00e+00	1107.00
IUUC-Ssc-115423	Sus scrofa	94.40	0.00e+00	1126.00
IUUC-Tgu-117050	Taeniopygia guttata	91.11	0.00e+00	1078.00
IUUC-Tru-118239	Takifugu rubripes	81.68	0.00e+00	972.00
IUUC-Tsy-119377	Tarsius syrichta	82.36	0.00e+00	976.00
IUUC-Tni-120122	Tetraodon nigroviridis	80.29	0.00e+00	873.00
IUUC-Vpa-130707	Vicugna pacos	91.63	0.00e+00	854.00
IUUC-Xtr-132035	Xenopus tropicalis	87.16	0.00e+00	1055.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence