iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023616

Ensembl Protein ID

ENSCSAP00000007189.1

UniProt Accession

A0A0D9RF00; A0A0D9RF00_CHLSB

Genbank Protein ID

ENSCSAP00000007189

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01116065

Gene Name

USP8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000010966.1	ENSCSAT00000009060.1	ENSCSAP00000007189.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-109	365.3	619	949

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmNS+LQcL n p l++++++  ++ ++n++n  ++kge+++++  ++++lw+++ +++sp++++ +++k++ +f gy+
   Q: 619  TGLRNLGNTCYMNSILQCLCNAPHLADYFNRnCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYS 707
           7*****************************9899******************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeee...dkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           qqD+qE+l fl+d+l+e+l+k +n ++ +ee++   d+ ++ ++a++k+k+ n+s+i+ lFqgq+ks+++cl+c+++s ++e f++lsl
   Q: 708  QQDSQELLLFLMDGLHEDLNKADNRKRYKEENNehlDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSL 796
           *******************8833333333222201144556666********************************************* PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldls 262
           p+ + +++   +lqdcL+ f+kee+l+++n++yc++c++++++ kk++++klP+vL +hLkRfs++ + ++ +k++++v+fple Ldls
   Q: 797  PLASTSKC---TLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGR-WK-QKLQTSVDFPLEnLDLS 880
           *******9...******************************************************996.55.6**************** PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           ++++ p+++    kkY+L++v +H+G+l++GHY+ay+kn  ++ W++fdD++V+ ++ ++v++   s aY+lfY+
   Q: 881  QYVIGPKNN---LKKYNLFSVSNHYGGLDGGHYTAYCKNAARQrWFKFDDHEVSDISVSSVKS---SAAYILFYT 949
           *****9988...69*************************88888*******************...********8 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MFCDLSASCA VSCHLYCLSQ FQGAITAKEL YTMMTDKNIS LIIMDARRMQ DYQDSCILHS 60
LSVPEEAISP GVTASWIEAH LPDDSKDTWK KRGNVEYVVL LDWFSSAKDL QIGTVLRSLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAATAAATG GTATGATTGG GTAGTAAATA TATGGCATCC TTATATATTC AGTATAATTT 60
GTTCTTCTAG AAAAAGCTGT TTGTCCTATG TTTTGTGATC TCAGCGCATC TTGTGCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00581--Rhodanese
PF00443--UCH

SMART

SM00450--RHOD

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0019897--C:extrinsic component of plasma membrane
GO:0030496--C:midbody
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007032--P:endosome organization
GO:0000281--P:mitotic cytokinesis
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	92.14	0.00e+00	1614.00
IUUC-Apl-003226	Anas platyrhynchos	77.27	0.00e+00	910.00
IUUC-Aca-004936	Anolis carolinensis	68.29	0.00e+00	1164.00
IUUC-Ago-007959	Ashbya gossypii	35.89	1.00e-54	207.00
IUUC-Acl-008102	Aspergillus clavatus	31.59	1.00e-50	195.00
IUUC-Afl-008604	Aspergillus flavus	31.32	8.00e-50	192.00
IUUC-Afu-009001	Aspergillus fumigatus	31.94	8.00e-50	192.00
IUUC-Ani-009291	Aspergillus nidulans	31.45	1.00e-49	192.00
IUUC-Ang-009844	Aspergillus niger	32.22	5.00e-49	189.00
IUUC-Aor-010098	Aspergillus oryzae	31.32	5.00e-49	189.00
IUUC-Ate-010585	Aspergillus terreus	31.22	5.00e-49	189.00
IUUC-Ame-010960	Astyanax mexicanus	76.67	2.00e-84	304.00
IUUC-Bta-013008	Bos taurus	88.07	0.00e+00	1546.00
IUUC-Bol-015281	Brassica oleracea	38.21	1.00e-46	180.00
IUUC-Bra-017228	Brassica rapa	39.10	2.00e-48	186.00
IUUC-Cel-018482	Caenorhabditis elegans	33.82	2.00e-51	197.00
IUUC-Cja-019173	Callithrix jacchus	97.12	0.00e+00	1702.00
IUUC-Cfa-021243	Canis familiaris	92.01	0.00e+00	1618.00
IUUC-Cpo-021522	Cavia porcellus	85.41	0.00e+00	1469.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	44.35	2.00e-81	296.00
IUUC-Cho-024381	Choloepus hoffmanni	80.67	0.00e+00	1370.00
IUUC-Cin-025287	Ciona intestinalis	49.87	1.00e-97	351.00
IUUC-Csv-026253	Ciona savignyi	47.78	3.00e-86	313.00
IUUC-Cne-026821	Cryptococcus neoformans	39.61	5.00e-74	273.00
IUUC-Dre-028440	Danio rerio	69.00	0.00e+00	729.00
IUUC-Dno-029039	Dasypus novemcinctus	91.37	0.00e+00	1630.00
IUUC-Dor-031043	Dipodomys ordii	96.12	4.00e-132	466.00
IUUC-Dse-031463	Dothistroma septosporum	28.65	8.00e-42	166.00
IUUC-Dme-032089	Drosophila melanogaster	45.43	7.00e-84	305.00
IUUC-Ete-033040	Echinops telfairi	81.61	0.00e+00	1295.00
IUUC-Eca-033449	Equus caballus	92.76	0.00e+00	1640.00
IUUC-Eeu-034693	Erinaceus europaeus	95.69	2.00e-130	460.00
IUUC-Fca-035794	Felis catus	98.74	0.00e+00	924.00
IUUC-Fal-037322	Ficedula albicollis	80.34	0.00e+00	909.00
IUUC-Gmo-038584	Gadus morhua	66.73	0.00e+00	659.00
IUUC-Gga-041188	Gallus gallus	83.19	0.00e+00	929.00
IUUC-Gac-041850	Gasterosteus aculeatus	73.05	0.00e+00	739.00
IUUC-Ggo-045565	Gorilla gorilla	98.20	0.00e+00	1726.00
IUUC-Hsa-046438	Homo sapiens	97.99	0.00e+00	1719.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	89.67	0.00e+00	1578.00
IUUC-Kpa-049321	Komagataella pastoris	33.51	8.00e-49	188.00
IUUC-Lch-050485	Latimeria chalumnae	84.31	0.00e+00	861.00
IUUC-Loc-052769	Lepisosteus oculatus	74.75	0.00e+00	764.00
IUUC-Lma-053021	Leptosphaeria maculans	32.80	2.00e-53	204.00
IUUC-Laf-053432	Loxodonta africana	85.92	0.00e+00	1029.00
IUUC-Mcc-055823	Macaca mulatta	99.26	0.00e+00	1738.00
IUUC-Meu-056099	Macropus eugenii	96.65	3.00e-162	566.00
IUUC-Mla-059089	Melampsora laricipopulina	40.18	3.00e-71	264.00
IUUC-Mga-059739	Meleagris gallopavo	82.84	0.00e+00	923.00
IUUC-Mvi-060559	Microbotryum violaceum	40.84	7.00e-76	279.00
IUUC-Mmr-061158	Microcebus murinus	91.66	0.00e+00	1618.00
IUUC-Mdo-061801	Monodelphis domestica	90.54	0.00e+00	1013.00
IUUC-Mmu-063665	Mus musculus	81.35	0.00e+00	1426.00
IUUC-Mpu-066738	Mustela putorius furo	92.41	0.00e+00	1613.00
IUUC-Mlu-067307	Myotis lucifugus	89.46	0.00e+00	1597.00
IUUC-Nfi-068410	Neosartorya fischeri	31.67	3.00e-50	194.00
IUUC-Nle-069314	Nomascus leucogenys	97.88	0.00e+00	1716.00
IUUC-Opr-070378	Ochotona princeps	85.69	0.00e+00	994.00
IUUC-Ont-071545	Oreochromis niloticus	76.47	0.00e+00	760.00
IUUC-Oan-073537	Ornithorhynchus anatinus	74.66	0.00e+00	1266.00
IUUC-Ocu-074193	Oryctolagus cuniculus	89.24	0.00e+00	1558.00
IUUC-Ola-086622	Oryzias latipes	56.56	0.00e+00	957.00
IUUC-Oga-088271	Otolemur garnettii	90.16	0.00e+00	1589.00
IUUC-Oar-090431	Ovis aries	88.22	0.00e+00	1551.00
IUUC-Ptr-091339	Pan troglodytes	97.67	0.00e+00	1748.00
IUUC-Pan-091783	Papio anubis	98.73	0.00e+00	807.00
IUUC-Psi-093187	Pelodiscus sinensis	76.47	4.00e-137	482.00
IUUC-Pma-094626	Petromyzon marinus	58.67	2.00e-141	495.00
IUUC-Pfo-096463	Poecilia formosa	75.46	0.00e+00	750.00
IUUC-Pab-097645	Pongo abelii	97.99	0.00e+00	1720.00
IUUC-Pva-103222	Pteropus vampyrus	93.83	0.00e+00	747.00
IUUC-Pgr-103408	Puccinia graminis	35.92	8.00e-54	206.00
IUUC-Ptt-103699	Puccinia triticina	46.15	9.00e-68	252.00
IUUC-Pte-104348	Pyrenophora teres	29.13	2.00e-39	157.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	31.39	7.00e-51	196.00
IUUC-Rno-105510	Rattus norvegicus	81.47	0.00e+00	1450.00
IUUC-Sce-106166	Saccharomyces cerevisiae	35.81	2.00e-51	197.00
IUUC-Sha-106879	Sarcophilus harrisii	88.89	0.00e+00	999.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	36.86	3.00e-48	186.00
IUUC-Sar-113019	Sorex araneus	83.07	0.00e+00	1482.00
IUUC-Sre-115031	Sporisorium reilianum	36.77	2.00e-68	254.00
IUUC-Ssc-116334	Sus scrofa	88.95	0.00e+00	1573.00
IUUC-Tgu-117062	Taeniopygia guttata	80.69	0.00e+00	912.00
IUUC-Tru-117908	Takifugu rubripes	57.64	0.00e+00	986.00
IUUC-Tsy-118867	Tarsius syrichta	88.76	0.00e+00	1094.00
IUUC-Tni-120206	Tetraodon nigroviridis	74.65	0.00e+00	726.00
IUUC-Tme-127144	Tuber melanosporum	40.00	8.00e-78	285.00
IUUC-Tbe-127877	Tupaia belangeri	89.30	6.00e-102	365.00
IUUC-Ttr-128580	Tursiops truncatus	86.26	0.00e+00	1468.00
IUUC-Uma-129340	Ustilago maydis	36.23	4.00e-71	263.00
IUUC-Vpa-130541	Vicugna pacos	90.52	0.00e+00	1593.00
IUUC-Xtr-132161	Xenopus tropicalis	58.78	0.00e+00	1031.00
IUUC-Xma-134271	Xiphophorus maculatus	75.46	0.00e+00	749.00
IUUC-Yli-134561	Yarrowia lipolytica	36.10	1.00e-59	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence