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Tag Content
UUCD2 ID IUUC-Ssc-115979
UUCD1 version UUC-SuS-00663
Ensembl Protein ID ENSSSCP00000005203.2
UniProt Accession F1SNS1; F1SNS1_PIG
Genbank Protein ID ENSSSCP00000005203
Protein Name Uncharacterized protein
Genbank Nucleotide ID CU856472
Gene Name UBE3A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000004832.2 ENSSSCT00000005334.2 ENSSSCP00000005203.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 3.60e-108 362.2 526 852
Active Site
Position(s) Description Evidence
821 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+vef+gE+g+d gGv++ef++l+++e++npd+g+f+y+e+ k  ++ np+s+    e +  F+++G++lg+a++++ +ld+
   Q: 526  PADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWF-NPSSF----ETEGQFTLIGIVLGLAIYNNCILDV 609
           689******************************************998888876.88888....789********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.lgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gkk ++ dl + +p ly+slk ++e+ e ++e+  + +tf++s++  +g+   ++Lk++G++ip+tneN++e+v+l+ 
   Q: 610  HFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEY-EGSVEDD-MMITFQISQTDlFGNPMMYDLKENGDKIPITNENRKEFVNLYS 696
           *************************************.6677775.999**9665444******************************* PP
   S: 179  eyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
           +y+l++++++q++afr+Gf+ v +++ l  lF++ee+ellicG++++d+++l+++t+y+ggyt+ds +i+ Fwe++++f++e+++ fLq
   Q: 697  DYILNKSVEKQFKAFRRGFHMVTNESpLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVVIREFWEIVHSFTDEQKRLFLQ 785
           ***********************99934558********************************************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           F+Tg++r+P+gG+ +lk   ++i k++ d +rlP+s+TCfn+L LPeYsske+lke+Ll Ai+++kgF++
   Q: 786  FTTGTDRAPVGGLGKLK---MIIAKNGPDtERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 852
           *****************...8888866666**************************************97 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
KRAAAKHLIE RYYHQLTEGC GNEACTNEFC ASCPTFRRMD NNAAAIKALE LYKINAKLCD 60
PHPSKKGASS AYLENSKGAP NNCSDIKMNR KEGQGARDDF KDVTYLTEET VYEILELCRE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-115979|E3,HECT|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGAGATCCG CGTTTTCCCA AGATGGTGGC GCTCGGCTCG GGGTGACTGC AGGAGAAGAC 60
AGCCTGAATC CCCTGCGCCA GAACCTCAAC ATACAGCCCT CCTCTCGCTC GCGCACCCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-115979|E3,HECT|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR032353--AZUL
IPR000569--HECT_dom
IPR017134--UBE3A
PROSITE

PS50237--HECT
Pfam

PF16558--AZUL
PF00632--HECT
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0030521--P:androgen receptor signaling pathway
GO:0001541--P:ovarian follicle development
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0060736--P:prostate gland growth
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042752--P:regulation of circadian rhythm
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035037--P:sperm entry
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002214 Ailuropoda melanoleuca 98.71 0.00e+00 1623.00
IUUC-Atr-003144 Amborella trichopoda 45.58 1.00e-95 343.00
IUUC-Apl-003742 Anas platyrhynchos 94.87 0.00e+00 1566.00
IUUC-Aca-004873 Anolis carolinensis 93.85 0.00e+00 1579.00
IUUC-Ame-011166 Astyanax mexicanus 86.23 0.00e+00 1452.00
IUUC-Bta-013286 Bos taurus 98.71 0.00e+00 1586.00
IUUC-Cja-019707 Callithrix jacchus 97.31 0.00e+00 1596.00
IUUC-Cfa-020154 Canis familiaris 98.13 0.00e+00 1597.00
IUUC-Cpo-021292 Cavia porcellus 96.72 0.00e+00 1598.00
IUUC-Cre-022790 Chlamydomonas reinhardtii 49.06 2.00e-82 298.00
IUUC-Csa-023378 Chlorocebus sabaeus 97.31 0.00e+00 1597.00
IUUC-Cho-025059 Choloepus hoffmanni 93.68 0.00e+00 1521.00
IUUC-Cin-025643 Ciona intestinalis 44.74 0.00e+00 717.00
IUUC-Csv-026282 Ciona savignyi 45.03 0.00e+00 679.00
IUUC-Cme-027151 Cyanidioschyzon merolae 44.02 2.00e-101 363.00
IUUC-Dre-027901 Danio rerio 85.16 0.00e+00 1432.00
IUUC-Dno-029320 Dasypus novemcinctus 97.54 0.00e+00 1605.00
IUUC-Dor-030756 Dipodomys ordii 93.58 0.00e+00 735.00
IUUC-Dme-032035 Drosophila melanogaster 43.16 4.00e-165 575.00
IUUC-Eca-033843 Equus caballus 97.78 0.00e+00 1575.00
IUUC-Eeu-035109 Erinaceus europaeus 95.90 0.00e+00 1561.00
IUUC-Fca-036344 Felis catus 96.73 0.00e+00 1597.00
IUUC-Fal-036747 Ficedula albicollis 94.87 0.00e+00 1568.00
IUUC-Gmo-038840 Gadus morhua 63.55 0.00e+00 1102.00
IUUC-Gga-040399 Gallus gallus 94.76 0.00e+00 1566.00
IUUC-Gac-041933 Gasterosteus aculeatus 85.26 0.00e+00 1387.00
IUUC-Ggo-044804 Gorilla gorilla 97.54 0.00e+00 1599.00
IUUC-Hsa-045727 Homo sapiens 97.54 0.00e+00 1599.00
IUUC-Itr-048289 Ictidomys tridecemlineatus 93.67 0.00e+00 1513.00
IUUC-Lch-050197 Latimeria chalumnae 91.23 0.00e+00 1533.00
IUUC-Loc-052743 Lepisosteus oculatus 89.74 0.00e+00 1514.00
IUUC-Lma-053245 Leptosphaeria maculans 33.87 4.00e-57 216.00
IUUC-Laf-053615 Loxodonta africana 96.37 0.00e+00 1593.00
IUUC-Mcc-054934 Macaca mulatta 97.31 0.00e+00 1595.00
IUUC-Meu-056061 Macropus eugenii 96.68 0.00e+00 1356.00
IUUC-Mga-059271 Meleagris gallopavo 94.76 0.00e+00 1562.00
IUUC-Mmr-061288 Microcebus murinus 97.31 0.00e+00 1597.00
IUUC-Mdo-062975 Monodelphis domestica 96.03 0.00e+00 1576.00
IUUC-Mmu-063674 Mus musculus 95.08 0.00e+00 1541.00
IUUC-Mpu-066568 Mustela putorius furo 98.48 0.00e+00 1624.00
IUUC-Mlu-067522 Myotis lucifugus 89.17 0.00e+00 1484.00
IUUC-Nle-069505 Nomascus leucogenys 97.54 0.00e+00 1599.00
IUUC-Opr-070570 Ochotona princeps 89.16 0.00e+00 1459.00
IUUC-Ont-071527 Oreochromis niloticus 85.85 0.00e+00 1462.00
IUUC-Oan-073446 Ornithorhynchus anatinus 90.29 0.00e+00 1026.00
IUUC-Ocu-074922 Oryctolagus cuniculus 95.35 0.00e+00 1591.00
IUUC-Ola-086996 Oryzias latipes 85.66 0.00e+00 1474.00
IUUC-Oga-088261 Otolemur garnettii 97.07 0.00e+00 1597.00
IUUC-Oar-090024 Ovis aries 98.71 0.00e+00 1586.00
IUUC-Ptr-090455 Pan troglodytes 97.54 0.00e+00 1599.00
IUUC-Pan-092509 Papio anubis 97.00 0.00e+00 1437.00
IUUC-Psi-092974 Pelodiscus sinensis 94.52 0.00e+00 1540.00
IUUC-Pma-094643 Petromyzon marinus 70.87 0.00e+00 1252.00
IUUC-Pno-094886 Phaeosphaeria nodorum 35.32 8.00e-58 219.00
IUUC-Pfo-096905 Poecilia formosa 85.25 0.00e+00 1453.00
IUUC-Pab-097840 Pongo abelii 95.20 0.00e+00 1555.00
IUUC-Pca-100869 Procavia capensis 95.79 0.00e+00 1577.00
IUUC-Pva-103040 Pteropus vampyrus 97.02 0.00e+00 667.00
IUUC-Rno-105453 Rattus norvegicus 94.84 0.00e+00 1540.00
IUUC-Sha-107651 Sarcophilus harrisii 96.03 0.00e+00 1576.00
IUUC-Smo-108858 Selaginella moellendorffii 49.88 2.00e-116 412.00
IUUC-Sar-113293 Sorex araneus 97.77 0.00e+00 1612.00
IUUC-Tgu-116901 Taeniopygia guttata 94.87 0.00e+00 1567.00
IUUC-Tru-118368 Takifugu rubripes 85.93 0.00e+00 1454.00
IUUC-Tsy-119516 Tarsius syrichta 93.09 0.00e+00 1486.00
IUUC-Tni-120143 Tetraodon nigroviridis 85.36 0.00e+00 1446.00
IUUC-Tbe-127484 Tupaia belangeri 91.65 0.00e+00 1098.00
IUUC-Ttr-129078 Tursiops truncatus 98.71 0.00e+00 1604.00
IUUC-Vpa-130312 Vicugna pacos 91.02 0.00e+00 1380.00
IUUC-Xtr-132881 Xenopus tropicalis 91.46 0.00e+00 1529.00
Created Date 25-Jun-2017

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