iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	21170036

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	2.20e-05	24.6	43	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 87   apaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktvt 147
           a apt    eg++ +++ ++ ++i+++i +++d+e+++++a++c+++++l  ++a+w++++
   Q: 43   ATAPTLPMAEGNN-NNVISMRYDIWFHISMHIDPEDVQTFALICKQTSRLVASRAFWRNLY 102
           6677765555555.5566789***************************77777****9986 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSFDADCDEF IKNKLFRSKG KCDIYARQSD VCVAVKQKST FRATAPTLPM AEGNNNNVIS 60
MRYDIWFHIS MHIDPEDVQT FALICKQTSR LVASRAFWRN LYRRHCTGAT SGWNLNLPAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACTCTGTCA CCACCTGACC AACTCGCAAG CAAACAACAG CTGTTGAACC AGCGAGAGCC 60
GAACACAATG AGTTTTGATG CCGATTGTGA TGAGTTTATT AAAAACAAAC TATTCCGTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR026509--TMEM183

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0009952--P:anterior/posterior pattern specification
GO:0035167--P:larval lymph gland hemopoiesis
GO:0016567--P:protein ubiquitination
GO:0031647--P:regulation of protein stability
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG12765

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000613	Aegilops tauschii	31.37	4.60e-02	32.00
IUUC-Aml-002076	Ailuropoda melanoleuca	24.90	6.00e-13	67.40
IUUC-Apl-003845	Anas platyrhynchos	23.90	3.00e-12	64.70
IUUC-Aca-005268	Anolis carolinensis	22.68	3.00e-13	68.60
IUUC-Aly-006426	Arabidopsis lyrata	44.44	2.20e-01	28.50
IUUC-Afl-008441	Aspergillus flavus	34.69	3.00e-02	28.50
IUUC-Ame-011069	Astyanax mexicanus	38.71	2.00e-11	62.80
IUUC-Bta-013107	Bos taurus	37.78	8.00e-12	63.90
IUUC-Cja-019351	Callithrix jacchus	25.68	8.00e-13	66.60
IUUC-Cfa-020658	Canis familiaris	25.29	9.00e-13	67.00
IUUC-Cpo-021328	Cavia porcellus	25.68	1.00e-13	70.10
IUUC-Csa-024122	Chlorocebus sabaeus	25.29	9.00e-13	67.00
IUUC-Cho-024846	Choloepus hoffmanni	36.26	2.00e-08	52.40
IUUC-Dre-027715	Danio rerio	25.58	4.00e-10	58.20
IUUC-Dno-029748	Dasypus novemcinctus	38.89	2.00e-12	65.90
IUUC-Dor-030755	Dipodomys ordii	38.89	1.00e-12	66.20
IUUC-Dse-031154	Dothistroma septosporum	40.00	5.30e-02	32.70
IUUC-Ete-032989	Echinops telfairi	39.56	1.00e-12	65.50
IUUC-Eca-033555	Equus caballus	24.90	4.00e-13	67.80
IUUC-Eeu-034623	Erinaceus europaeus	25.29	7.00e-13	67.40
IUUC-Fca-036223	Felis catus	24.51	7.00e-13	67.40
IUUC-Fal-037050	Ficedula albicollis	24.41	1.00e-12	66.20
IUUC-Gmo-039312	Gadus morhua	24.90	1.00e-12	66.60
IUUC-Ggr-039792	Gaeumannomyces graminis	26.39	2.90e-02	32.70
IUUC-Gga-040654	Gallus gallus	23.53	2.00e-11	62.80
IUUC-Gac-041693	Gasterosteus aculeatus	25.38	3.00e-12	65.10
IUUC-Ggo-044483	Gorilla gorilla	25.29	8.00e-13	67.00
IUUC-Hsa-046187	Homo sapiens	25.29	9.00e-13	67.00
IUUC-Itr-048761	Ictidomys tridecemlineatus	26.07	1.00e-13	69.70
IUUC-Lch-050044	Latimeria chalumnae	38.04	4.00e-10	58.20
IUUC-Loc-052001	Lepisosteus oculatus	25.29	8.00e-14	70.50
IUUC-Laf-054436	Loxodonta africana	25.29	6.00e-13	67.80
IUUC-Mcc-055296	Macaca mulatta	32.22	7.00e-08	50.40
IUUC-Meu-056032	Macropus eugenii	36.67	5.00e-07	47.80
IUUC-Mga-059804	Meleagris gallopavo	23.53	1.00e-11	62.80
IUUC-Mmr-061627	Microcebus murinus	38.89	1.00e-12	66.60
IUUC-Mdo-062201	Monodelphis domestica	24.71	1.00e-12	67.00
IUUC-Mmu-064143	Mus musculus	25.29	3.00e-13	68.60
IUUC-Mpu-066727	Mustela putorius furo	38.89	2.00e-12	66.20
IUUC-Mlu-067490	Myotis lucifugus	38.89	2.00e-12	65.90
IUUC-Nle-069576	Nomascus leucogenys	25.29	9.00e-13	67.00
IUUC-Opr-070909	Ochotona princeps	25.49	2.00e-13	68.20
IUUC-Ont-071432	Oreochromis niloticus	24.81	2.00e-12	66.20
IUUC-Oan-072741	Ornithorhynchus anatinus	25.29	5.00e-14	71.20
IUUC-Ocu-074549	Oryctolagus cuniculus	25.29	9.00e-13	67.00
IUUC-Oba-075511	Oryza barthii	30.19	1.90e-01	30.40
IUUC-Oni-082248	Oryza nivara	29.87	4.20e-02	32.30
IUUC-Oru-084300	Oryza rufipogon	31.58	2.80e-01	30.40
IUUC-Ola-086758	Oryzias latipes	25.10	1.00e-13	70.10
IUUC-Oga-088093	Otolemur garnettii	38.89	1.00e-12	66.20
IUUC-Oar-089290	Ovis aries	37.78	8.00e-12	63.90
IUUC-Ptr-091428	Pan troglodytes	25.29	9.00e-13	67.00
IUUC-Pan-092107	Papio anubis	25.29	7.00e-13	67.40
IUUC-Psi-093272	Pelodiscus sinensis	24.12	7.00e-13	67.00
IUUC-Pma-094126	Petromyzon marinus	23.40	7.00e-11	60.50
IUUC-Pfo-096098	Poecilia formosa	25.48	7.00e-13	67.00
IUUC-Pab-097996	Pongo abelii	25.29	9.00e-13	67.00
IUUC-Pop-099194	Populus trichocarpa	32.61	4.20e-02	32.30
IUUC-Pca-101067	Procavia capensis	35.85	6.00e-13	67.40
IUUC-Pva-102170	Pteropus vampyrus	24.51	7.00e-11	60.80
IUUC-Ptt-103945	Puccinia triticina	33.33	9.60e-02	31.60
IUUC-Rno-105181	Rattus norvegicus	24.90	3.00e-13	68.60
IUUC-Sha-106903	Sarcophilus harrisii	24.71	1.00e-12	67.00
IUUC-Stu-112604	Solanum tuberosum	34.62	1.50e-02	31.60
IUUC-Ssc-116162	Sus scrofa	24.51	1.00e-09	56.20
IUUC-Tgu-117053	Taeniopygia guttata	25.19	1.00e-13	69.70
IUUC-Tru-118353	Takifugu rubripes	22.91	1.00e-11	63.50
IUUC-Tsy-119458	Tarsius syrichta	25.29	7.00e-13	67.40
IUUC-Tni-119990	Tetraodon nigroviridis	24.90	5.00e-13	67.80
IUUC-Tae-123247	Triticum aestivum	31.75	3.00e-03	35.40
IUUC-Tbe-127741	Tupaia belangeri	32.80	1.00e-12	66.60
IUUC-Ttr-128670	Tursiops truncatus	25.29	8.00e-13	67.00
IUUC-Vpa-130181	Vicugna pacos	45.00	8.00e-06	43.50
IUUC-Xtr-132531	Xenopus tropicalis	37.21	2.00e-09	55.50
IUUC-Xma-134079	Xiphophorus maculatus	25.67	2.00e-12	65.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence