iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004062

Ensembl Protein ID

ENSAPLP00000013298.1

UniProt Accession

U3J1C1; U3J1C1_ANAPL

Genbank Protein ID

ENSAPLP00000013298

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01015940

Gene Name

TRAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000013488.1	ENSAPLT00000014047.1	ENSAPLP00000013298.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.20e-06	26.2	69	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrli 65
           + + CpI l   r+ v +p+G+ + + +I k +    + g+ +cPv+++ l e++l P ++ +r i
   Q: 69   SKYECPICLMALREAVQTPCGHRFCKGCIVKSIrhcrDAGH-KCPVDNEILLENQLFPDNFAKREI 133
           5689**********************999987744424444.6*****************999977 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MSLLQSNNSC GARDLESGCC AARATMASAC SVGAKEDSVS VSSGTGNPPS SFTEETQGYD 60
VEFDPPLESK YECPICLMAL REAVQTPCGH RFCKGCIVKS IRHCRDAGHK CPVDNEILLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTTGC TACAGAGCAA TAACAGTTGT GGAGCCCGAG ACCTGGAAAG TGGCTGCTGT 60
GCAGCCAGGG CCAGCGCNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0009887--P:animal organ morphogenesis
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453--P:bone resorption
GO:0048468--P:cell development
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0043011--P:myeloid dendritic cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0001843--P:neural tube closure
GO:0001503--P:ossification
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084--P:positive regulation of interleukin-12 biosynthetic process
GO:0032743--P:positive regulation of interleukin-2 production
GO:0045410--P:positive regulation of interleukin-6 biosynthetic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0031666--P:positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045672--P:positive regulation of osteoclast differentiation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051023--P:regulation of immunoglobulin secretion
GO:0050852--P:T cell receptor signaling pathway
GO:0042088--P:T-helper 1 type immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	32.46	4.00e-08	52.00
IUUC-Aml-001262	Ailuropoda melanoleuca	73.87	0.00e+00	795.00
IUUC-Aca-004636	Anolis carolinensis	75.99	0.00e+00	835.00
IUUC-Ame-011682	Astyanax mexicanus	54.03	3.00e-161	561.00
IUUC-Bgr-012191	Blumeria graminis	27.13	4.00e-16	79.00
IUUC-Bta-012692	Bos taurus	73.33	0.00e+00	809.00
IUUC-Cja-019426	Callithrix jacchus	71.87	0.00e+00	788.00
IUUC-Cfa-020948	Canis familiaris	73.35	0.00e+00	712.00
IUUC-Cpo-021378	Cavia porcellus	72.55	0.00e+00	791.00
IUUC-Csa-024045	Chlorocebus sabaeus	71.87	0.00e+00	806.00
IUUC-Cho-024973	Choloepus hoffmanni	60.73	7.00e-83	300.00
IUUC-Csv-026300	Ciona savignyi	39.61	5.00e-48	183.00
IUUC-Dre-027557	Danio rerio	59.27	6.00e-176	610.00
IUUC-Dno-030032	Dasypus novemcinctus	69.35	2.00e-120	424.00
IUUC-Dor-030790	Dipodomys ordii	72.41	0.00e+00	794.00
IUUC-Dme-031921	Drosophila melanogaster	27.47	3.00e-38	152.00
IUUC-Ete-032952	Echinops telfairi	70.55	2.00e-146	511.00
IUUC-Eca-033924	Equus caballus	69.62	0.00e+00	723.00
IUUC-Eeu-034734	Erinaceus europaeus	64.67	0.00e+00	679.00
IUUC-Fca-036222	Felis catus	69.02	0.00e+00	713.00
IUUC-Fal-036834	Ficedula albicollis	94.93	0.00e+00	942.00
IUUC-Fox-037935	Fusarium oxysporum	31.31	8.00e-23	101.00
IUUC-Gmo-039061	Gadus morhua	62.00	1.00e-88	320.00
IUUC-Ggr-040084	Gaeumannomyces graminis	26.92	3.00e-14	73.20
IUUC-Gga-040599	Gallus gallus	95.28	0.00e+00	1094.00
IUUC-Gac-041977	Gasterosteus aculeatus	57.88	7.00e-175	606.00
IUUC-Ggo-044508	Gorilla gorilla	67.57	0.00e+00	725.00
IUUC-Hsa-046349	Homo sapiens	72.60	0.00e+00	830.00
IUUC-Hvu-047127	Hordeum vulgare	34.67	3.00e-07	48.90
IUUC-Itr-047966	Ictidomys tridecemlineatus	72.78	0.00e+00	820.00
IUUC-Lch-049821	Latimeria chalumnae	69.86	0.00e+00	788.00
IUUC-Loc-051995	Lepisosteus oculatus	61.60	0.00e+00	636.00
IUUC-Laf-054115	Loxodonta africana	72.60	0.00e+00	808.00
IUUC-Mcc-055298	Macaca mulatta	71.51	0.00e+00	800.00
IUUC-Mor-057263	Magnaporthe oryzae	31.36	4.00e-20	92.40
IUUC-Mpo-057517	Magnaporthe poae	30.33	6.00e-17	82.00
IUUC-Mga-059340	Meleagris gallopavo	95.10	0.00e+00	1070.00
IUUC-Mvi-060553	Microbotryum violaceum	28.64	8.00e-18	84.70
IUUC-Mmr-061063	Microcebus murinus	73.36	0.00e+00	805.00
IUUC-Mdo-062075	Monodelphis domestica	73.50	0.00e+00	828.00
IUUC-Mmu-063780	Mus musculus	73.55	0.00e+00	774.00
IUUC-Mpu-065748	Mustela putorius furo	74.36	0.00e+00	808.00
IUUC-Mlu-067888	Myotis lucifugus	74.22	0.00e+00	796.00
IUUC-Ncr-068632	Neurospora crassa	24.42	3.00e-14	73.20
IUUC-Nle-069234	Nomascus leucogenys	71.51	0.00e+00	803.00
IUUC-Opr-070393	Ochotona princeps	79.34	1.00e-102	366.00
IUUC-Ont-072459	Oreochromis niloticus	55.22	0.00e+00	626.00
IUUC-Oan-073578	Ornithorhynchus anatinus	76.46	0.00e+00	854.00
IUUC-Ocu-074201	Oryctolagus cuniculus	72.79	0.00e+00	800.00
IUUC-Ome-081269	Oryza meridionalis	29.31	3.00e-07	48.90
IUUC-Oni-083040	Oryza nivara	34.67	9.00e-07	47.00
IUUC-Ola-087319	Oryzias latipes	58.27	4.00e-90	325.00
IUUC-Olu-087748	Ostreococcus lucimarinus	22.36	3.00e-09	55.50
IUUC-Oga-087936	Otolemur garnettii	71.69	0.00e+00	790.00
IUUC-Oar-089379	Ovis aries	73.45	0.00e+00	813.00
IUUC-Ptr-090758	Pan troglodytes	71.87	0.00e+00	805.00
IUUC-Pan-092590	Papio anubis	71.69	0.00e+00	801.00
IUUC-Psi-093948	Pelodiscus sinensis	82.28	0.00e+00	930.00
IUUC-Pma-094434	Petromyzon marinus	44.37	2.00e-130	459.00
IUUC-Pfo-096912	Poecilia formosa	58.45	7.00e-173	600.00
IUUC-Pab-097651	Pongo abelii	71.87	0.00e+00	807.00
IUUC-Pca-100958	Procavia capensis	70.71	2.00e-171	594.00
IUUC-Pva-103247	Pteropus vampyrus	74.03	6.00e-106	377.00
IUUC-Pte-104279	Pyrenophora teres	26.64	3.00e-14	73.60
IUUC-Pyt-104429	Pyrenophora triticirepentis	26.94	2.00e-13	70.10
IUUC-Rno-104994	Rattus norvegicus	73.69	0.00e+00	791.00
IUUC-Sha-106494	Sarcophilus harrisii	74.77	0.00e+00	843.00
IUUC-Sar-113375	Sorex araneus	73.01	0.00e+00	791.00
IUUC-Sbi-113900	Sorghum bicolor	34.67	2.00e-07	49.70
IUUC-Sre-115218	Sporisorium reilianum	29.34	1.00e-18	87.80
IUUC-Ssc-115417	Sus scrofa	74.05	0.00e+00	818.00
IUUC-Tgu-117232	Taeniopygia guttata	90.91	0.00e+00	1002.00
IUUC-Tru-118321	Takifugu rubripes	57.65	3.00e-177	614.00
IUUC-Tni-120475	Tetraodon nigroviridis	58.10	3.00e-169	588.00
IUUC-Tur-126067	Triticum urartu	31.62	5.00e-08	51.20
IUUC-Tbe-127719	Tupaia belangeri	62.93	0.00e+00	661.00
IUUC-Ttr-129264	Tursiops truncatus	73.64	6.00e-103	367.00
IUUC-Uma-129620	Ustilago maydis	26.54	8.00e-17	82.00
IUUC-Vpa-130244	Vicugna pacos	75.58	2.00e-108	385.00
IUUC-Xtr-131948	Xenopus tropicalis	68.56	0.00e+00	767.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence