iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022166

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02017908

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008227.3	ENSCPOT00000008302.2	ENSCPOP00000007397.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.27	0.00e+00	751.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QVRPKLPLLK ILQAAGAQGE MFTVKEVMHY LGQYIMVKQL YDPREQHMVY CGGDLLGELL 60
GRQSFSVKEP SPLYDMLRKN LVTLATAATD AAQTLALAQD HSMDIPSQDQ PKQNAQGSSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTACGAC CAAAACTTCC GCTTTTGAAG ATATTGCAGG CAGCAGGTGC ACAAGGTGAA 60
ATGTTCACCG TTAAAGAGGT AAGACATCAA AGAAATTCTC AGTTTTAAGA ACAGTTGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	88.65	0.00e+00	729.00
IUUC-Apl-003800	Anas platyrhynchos	59.74	1.00e-143	503.00
IUUC-Aca-004608	Anolis carolinensis	54.72	3.00e-128	451.00
IUUC-Ame-010869	Astyanax mexicanus	46.93	3.00e-101	362.00
IUUC-Bta-013287	Bos taurus	86.05	0.00e+00	785.00
IUUC-Cja-019305	Callithrix jacchus	87.34	0.00e+00	742.00
IUUC-Cfa-020393	Canis familiaris	89.72	0.00e+00	758.00
IUUC-Csa-023654	Chlorocebus sabaeus	89.27	0.00e+00	735.00
IUUC-Cho-024403	Choloepus hoffmanni	86.14	6.00e-124	437.00
IUUC-Dre-027754	Danio rerio	48.44	2.00e-108	385.00
IUUC-Dno-029630	Dasypus novemcinctus	85.22	0.00e+00	741.00
IUUC-Dor-031064	Dipodomys ordii	67.38	5.00e-173	600.00
IUUC-Ete-032901	Echinops telfairi	75.59	0.00e+00	701.00
IUUC-Eca-034234	Equus caballus	89.70	0.00e+00	823.00
IUUC-Eeu-035015	Erinaceus europaeus	63.52	5.00e-148	517.00
IUUC-Fca-036587	Felis catus	89.06	0.00e+00	770.00
IUUC-Fal-036906	Ficedula albicollis	52.45	6.00e-126	444.00
IUUC-Gmo-038646	Gadus morhua	43.51	3.00e-89	322.00
IUUC-Gga-040124	Gallus gallus	57.18	2.00e-111	395.00
IUUC-Gac-042397	Gasterosteus aculeatus	45.55	2.00e-103	369.00
IUUC-Ggo-045505	Gorilla gorilla	89.27	0.00e+00	749.00
IUUC-Hsa-046950	Homo sapiens	89.27	0.00e+00	750.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	89.27	0.00e+00	775.00
IUUC-Lch-050141	Latimeria chalumnae	52.52	1.00e-112	400.00
IUUC-Loc-051921	Lepisosteus oculatus	48.65	7.00e-105	374.00
IUUC-Laf-054281	Loxodonta africana	85.41	0.00e+00	746.00
IUUC-Mcc-055462	Macaca mulatta	86.18	0.00e+00	690.00
IUUC-Meu-056294	Macropus eugenii	71.14	1.00e-131	462.00
IUUC-Mga-059924	Meleagris gallopavo	59.40	9.00e-154	536.00
IUUC-Mmr-061428	Microcebus murinus	88.20	0.00e+00	795.00
IUUC-Mdo-062643	Monodelphis domestica	74.79	0.00e+00	671.00
IUUC-Mmu-063229	Mus musculus	81.97	0.00e+00	720.00
IUUC-Mpu-065782	Mustela putorius furo	87.18	0.00e+00	739.00
IUUC-Mlu-068105	Myotis lucifugus	78.11	0.00e+00	706.00
IUUC-Nle-069549	Nomascus leucogenys	89.70	0.00e+00	754.00
IUUC-Opr-070568	Ochotona princeps	88.60	0.00e+00	765.00
IUUC-Ont-072276	Oreochromis niloticus	46.73	3.00e-108	385.00
IUUC-Oan-072787	Ornithorhynchus anatinus	71.73	0.00e+00	637.00
IUUC-Ocu-074912	Oryctolagus cuniculus	90.34	0.00e+00	783.00
IUUC-Ola-087037	Oryzias latipes	44.74	7.00e-93	334.00
IUUC-Oga-088953	Otolemur garnettii	84.68	0.00e+00	738.00
IUUC-Oar-089202	Ovis aries	86.27	0.00e+00	788.00
IUUC-Ptr-090964	Pan troglodytes	89.27	0.00e+00	749.00
IUUC-Pan-091975	Papio anubis	89.48	0.00e+00	754.00
IUUC-Psi-093558	Pelodiscus sinensis	59.01	4.00e-148	517.00
IUUC-Pfo-096454	Poecilia formosa	47.72	1.00e-107	383.00
IUUC-Pab-098123	Pongo abelii	89.70	0.00e+00	756.00
IUUC-Pca-101112	Procavia capensis	76.18	0.00e+00	670.00
IUUC-Pva-103098	Pteropus vampyrus	80.26	0.00e+00	715.00
IUUC-Rno-105930	Rattus norvegicus	81.97	0.00e+00	690.00
IUUC-Sha-107512	Sarcophilus harrisii	73.66	8.00e-174	603.00
IUUC-Sar-113584	Sorex araneus	78.76	0.00e+00	672.00
IUUC-Tgu-116766	Taeniopygia guttata	55.14	1.00e-98	352.00
IUUC-Tru-117829	Takifugu rubripes	47.27	3.00e-109	388.00
IUUC-Tsy-119268	Tarsius syrichta	78.41	1.00e-178	619.00
IUUC-Tni-120204	Tetraodon nigroviridis	46.80	2.00e-105	375.00
IUUC-Tbe-127840	Tupaia belangeri	82.85	8.00e-121	426.00
IUUC-Ttr-128863	Tursiops truncatus	86.05	0.00e+00	756.00
IUUC-Vpa-130718	Vicugna pacos	87.31	0.00e+00	765.00
IUUC-Xtr-132320	Xenopus tropicalis	45.68	5.00e-87	314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence