iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089559

Ensembl Protein ID

ENSOARP00000021501.1

UniProt Accession

W5QFK3; W5QFK3_SHEEP

Genbank Protein ID

ENSOARP00000021501

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01076212

Gene Name

PELI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020025.1	ENSOART00000021803.1	ENSOARP00000021501.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	100.00	0.00e+00	880.00	IUUC-Hsa-046261
E3 activity/RING/RING	99.76	0.00e+00	879.00	IUUC-Mmu-063411
E3 activity/RING/RING	59.62	8.00e-146	508.00	IUUC-Ots-000053

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

LMFSPDQENH PSKAPVKYGE LIVLGYNGSL PNGDRGRRKS RFALFKRPKA NGVKPSTVHI 60
ACTPQAAKAI SNKDQHSISY TLSRAQTVVV EYTHDSNTDM FQIGRSTESP IDFVVTDTVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATAATGC AAAAGGTGTC CCAAGGCTCC TGACCAGTGA ACAAAGATTT GAGAAAGACA 60
GCCAAGCTCA TGTTTTCTCC TGATCAAGAA AATCATCCAT CCAAAGCACC AGTGAAATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006800--Pellino_fam
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF04710--Pellino

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042130--P:negative regulation of T cell proliferation
GO:0030890--P:positive regulation of B cell proliferation
GO:0001819--P:positive regulation of cytokine production
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0031398--P:positive regulation of protein ubiquitination
GO:0034141--P:positive regulation of toll-like receptor 3 signaling pathway
GO:0034145--P:positive regulation of toll-like receptor 4 signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0043331--P:response to dsRNA
GO:0032496--P:response to lipopolysaccharide
GO:0008063--P:Toll signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001486	Ailuropoda melanoleuca	100.00	0.00e+00	880.00
IUUC-Apl-003642	Anas platyrhynchos	99.28	0.00e+00	879.00
IUUC-Aca-004878	Anolis carolinensis	97.85	0.00e+00	864.00
IUUC-Ame-011117	Astyanax mexicanus	85.38	0.00e+00	771.00
IUUC-Bta-012657	Bos taurus	99.52	0.00e+00	877.00
IUUC-Bci-013893	Botrytis cinerea	28.89	1.40e-01	30.80
IUUC-Cel-018562	Caenorhabditis elegans	44.36	8.00e-101	360.00
IUUC-Cja-019539	Callithrix jacchus	99.76	0.00e+00	880.00
IUUC-Cfa-020479	Canis familiaris	99.76	0.00e+00	880.00
IUUC-Cpo-021657	Cavia porcellus	99.52	0.00e+00	874.00
IUUC-Csa-023842	Chlorocebus sabaeus	100.00	0.00e+00	880.00
IUUC-Cho-025068	Choloepus hoffmanni	99.43	0.00e+00	739.00
IUUC-Cin-025429	Ciona intestinalis	56.24	3.00e-137	481.00
IUUC-Csv-026180	Ciona savignyi	57.52	1.00e-136	479.00
IUUC-Dre-028217	Danio rerio	89.18	0.00e+00	791.00
IUUC-Dno-029357	Dasypus novemcinctus	80.66	0.00e+00	743.00
IUUC-Dor-030597	Dipodomys ordii	99.52	0.00e+00	879.00
IUUC-Dse-031384	Dothistroma septosporum	25.66	4.00e-03	36.20
IUUC-Dme-031916	Drosophila melanogaster	58.81	4.00e-145	507.00
IUUC-Ete-032925	Echinops telfairi	99.52	0.00e+00	877.00
IUUC-Eca-034037	Equus caballus	99.76	0.00e+00	879.00
IUUC-Eeu-034920	Erinaceus europaeus	81.98	0.00e+00	704.00
IUUC-Fca-036415	Felis catus	100.00	0.00e+00	880.00
IUUC-Fal-037444	Ficedula albicollis	99.28	0.00e+00	874.00
IUUC-Fox-037816	Fusarium oxysporum	34.04	2.80e-02	33.10
IUUC-Gmo-039248	Gadus morhua	78.55	0.00e+00	691.00
IUUC-Gga-040551	Gallus gallus	99.28	0.00e+00	874.00
IUUC-Gac-041981	Gasterosteus aculeatus	72.13	0.00e+00	654.00
IUUC-Ggo-045270	Gorilla gorilla	100.00	0.00e+00	880.00
IUUC-Hsa-046261	Homo sapiens	100.00	0.00e+00	880.00
IUUC-Itr-047919	Ictidomys tridecemlineatus	100.00	0.00e+00	880.00
IUUC-Kpa-049153	Komagataella pastoris	31.15	1.40e+00	29.60
IUUC-Lch-050683	Latimeria chalumnae	81.19	0.00e+00	738.00
IUUC-Loc-052528	Lepisosteus oculatus	92.14	0.00e+00	825.00
IUUC-Laf-054201	Loxodonta africana	99.28	0.00e+00	876.00
IUUC-Mcc-054979	Macaca mulatta	81.98	0.00e+00	704.00
IUUC-Meu-056175	Macropus eugenii	72.38	0.00e+00	651.00
IUUC-Mga-059547	Meleagris gallopavo	99.05	0.00e+00	877.00
IUUC-Mmr-060621	Microcebus murinus	81.77	0.00e+00	627.00
IUUC-Mdo-062133	Monodelphis domestica	99.28	0.00e+00	877.00
IUUC-Mmu-063411	Mus musculus	99.76	0.00e+00	879.00
IUUC-Mac-065171	Musa acuminata	27.69	1.90e-01	29.60
IUUC-Mpu-066566	Mustela putorius furo	100.00	0.00e+00	880.00
IUUC-Mlu-067015	Myotis lucifugus	99.76	0.00e+00	880.00
IUUC-Nle-069510	Nomascus leucogenys	100.00	0.00e+00	880.00
IUUC-Ont-072324	Oreochromis niloticus	87.09	0.00e+00	776.00
IUUC-Oan-073059	Ornithorhynchus anatinus	99.28	0.00e+00	878.00
IUUC-Ocu-073888	Oryctolagus cuniculus	99.70	0.00e+00	705.00
IUUC-Ola-086600	Oryzias latipes	86.15	0.00e+00	770.00
IUUC-Oga-088926	Otolemur garnettii	99.76	0.00e+00	880.00
IUUC-Ptr-090954	Pan troglodytes	99.52	0.00e+00	876.00
IUUC-Pan-092719	Papio anubis	100.00	0.00e+00	880.00
IUUC-Psi-093982	Pelodiscus sinensis	99.04	0.00e+00	874.00
IUUC-Pma-094346	Petromyzon marinus	63.23	5.00e-155	540.00
IUUC-Pno-095123	Phaeosphaeria nodorum	32.69	3.30e-02	32.30
IUUC-Pfo-097047	Poecilia formosa	88.26	0.00e+00	784.00
IUUC-Pab-097906	Pongo abelii	100.00	0.00e+00	880.00
IUUC-Pca-101126	Procavia capensis	98.48	0.00e+00	813.00
IUUC-Pva-102764	Pteropus vampyrus	81.67	0.00e+00	743.00
IUUC-Rno-105984	Rattus norvegicus	99.76	0.00e+00	879.00
IUUC-Sha-107581	Sarcophilus harrisii	80.60	0.00e+00	704.00
IUUC-Sar-112939	Sorex araneus	99.50	0.00e+00	843.00
IUUC-Ssc-115320	Sus scrofa	100.00	0.00e+00	882.00
IUUC-Tgu-116492	Taeniopygia guttata	98.81	0.00e+00	875.00
IUUC-Tru-118750	Takifugu rubripes	86.62	0.00e+00	767.00
IUUC-Tsy-119254	Tarsius syrichta	100.00	0.00e+00	845.00
IUUC-Tni-119865	Tetraodon nigroviridis	87.44	0.00e+00	728.00
IUUC-Tre-122231	Trichoderma reesei	34.00	1.40e-01	30.80
IUUC-Tae-124278	Triticum aestivum	31.73	1.80e-02	34.30
IUUC-Tbe-127454	Tupaia belangeri	91.87	0.00e+00	800.00
IUUC-Ttr-129040	Tursiops truncatus	99.52	0.00e+00	876.00
IUUC-Vpa-130078	Vicugna pacos	99.76	0.00e+00	874.00
IUUC-Xtr-131992	Xenopus tropicalis	97.14	0.00e+00	862.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence