iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF	PHOSIDA
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.90e-13	49.6	504	555

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++lydy+a++dde ++   dv++ i  e+ d gW++g    +++ GlfP+n+v+ +
   Q: 504  IALYDYQAADDDEISFDPDDVITHI--EKIDDGWWRG--LCKNRYGLFPANYVQVV 555
           79***********************..9*********..9*************987 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MWKASAGHQI QATSAASAED DDWETDPDFV NDVSEQEQRW GSKTIDGSGR TAGTIDMDKL 60
REETEQADLD KKKQLLKDQN AGYGYGGKFG VEKDRMDKSA VGHDYQGKVG KHASQKDYSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTCGTAGC ATATCGATGC ATCCATTGTA TCGAATGAAA TTTAGTTCAG TTAGTTTCCC 60
GTTTGTTGGT CTCTTTATGA ATCAATTGTT TAACCCTTCT CCTCCCAGAA ATTTGCAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0030478--C:actin cap
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0070864--C:sperm individualization complex
GO:0070064--F:proline-rich region binding
GO:0007298--P:border follicle cell migration
GO:0007301--P:female germline ring canal formation
GO:0048260--P:positive regulation of receptor-mediated endocytosis
GO:0008360--P:regulation of cell shape

KEGG

dme:Dmel_CG3637

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	62.61	1.00e-75	276.00
IUUC-Apl-003745	Anas platyrhynchos	63.04	3.00e-67	248.00
IUUC-Aca-004438	Anolis carolinensis	55.22	3.00e-74	271.00
IUUC-Ame-011504	Astyanax mexicanus	59.13	2.00e-62	232.00
IUUC-Bta-013563	Bos taurus	61.74	3.00e-74	271.00
IUUC-Cja-019982	Callithrix jacchus	52.94	2.00e-71	261.00
IUUC-Cfa-020718	Canis familiaris	62.61	9.00e-76	276.00
IUUC-Cpo-022303	Cavia porcellus	41.98	5.00e-105	374.00
IUUC-Csa-023431	Chlorocebus sabaeus	63.04	3.00e-76	278.00
IUUC-Cin-025677	Ciona intestinalis	59.23	3.00e-63	235.00
IUUC-Csv-026140	Ciona savignyi	44.51	4.00e-61	228.00
IUUC-Dre-028012	Danio rerio	61.04	4.00e-76	278.00
IUUC-Dno-029332	Dasypus novemcinctus	63.04	1.00e-75	276.00
IUUC-Dor-030437	Dipodomys ordii	46.40	2.00e-55	208.00
IUUC-Ete-033160	Echinops telfairi	44.02	2.00e-45	175.00
IUUC-Eca-033801	Equus caballus	63.04	3.00e-76	278.00
IUUC-Eeu-035032	Erinaceus europaeus	41.06	3.00e-23	102.00
IUUC-Fca-035999	Felis catus	47.17	1.00e-74	272.00
IUUC-Fal-036775	Ficedula albicollis	61.30	7.00e-67	247.00
IUUC-Gga-040335	Gallus gallus	60.87	1.00e-77	283.00
IUUC-Gac-042253	Gasterosteus aculeatus	45.65	2.00e-70	259.00
IUUC-Ggo-044505	Gorilla gorilla	54.18	1.00e-73	269.00
IUUC-Hsa-046818	Homo sapiens	62.61	4.00e-76	278.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	63.91	4.00e-77	281.00
IUUC-Lch-050221	Latimeria chalumnae	61.74	1.00e-77	283.00
IUUC-Loc-052855	Lepisosteus oculatus	60.43	6.00e-75	274.00
IUUC-Laf-053866	Loxodonta africana	62.61	8.00e-76	276.00
IUUC-Mcc-055515	Macaca mulatta	62.61	7.00e-76	277.00
IUUC-Mga-059791	Meleagris gallopavo	63.04	7.00e-67	247.00
IUUC-Mmr-061147	Microcebus murinus	62.17	3.00e-75	275.00
IUUC-Mdo-062515	Monodelphis domestica	51.54	3.00e-69	254.00
IUUC-Mmu-064023	Mus musculus	62.61	8.00e-76	276.00
IUUC-Mpu-065867	Mustela putorius furo	62.61	2.00e-75	275.00
IUUC-Mlu-067704	Myotis lucifugus	62.61	2.00e-75	275.00
IUUC-Nle-069436	Nomascus leucogenys	54.18	5.00e-74	271.00
IUUC-Opr-070288	Ochotona princeps	54.84	1.00e-53	203.00
IUUC-Ont-071712	Oreochromis niloticus	58.26	7.00e-70	257.00
IUUC-Oan-073528	Ornithorhynchus anatinus	52.04	6.00e-54	204.00
IUUC-Ocu-074686	Oryctolagus cuniculus	54.40	6.00e-72	263.00
IUUC-Ola-086894	Oryzias latipes	58.15	1.00e-71	263.00
IUUC-Oga-088028	Otolemur garnettii	63.04	2.00e-76	279.00
IUUC-Oar-089686	Ovis aries	54.40	2.00e-72	265.00
IUUC-Ptr-090461	Pan troglodytes	54.18	1.00e-73	269.00
IUUC-Pan-092594	Papio anubis	62.61	4.00e-76	278.00
IUUC-Psi-093785	Pelodiscus sinensis	50.00	2.00e-77	282.00
IUUC-Pma-094161	Petromyzon marinus	52.10	8.00e-43	167.00
IUUC-Pfo-097391	Poecilia formosa	57.64	1.00e-70	259.00
IUUC-Pab-097913	Pongo abelii	62.61	6.00e-76	277.00
IUUC-Pca-100668	Procavia capensis	48.87	2.00e-68	252.00
IUUC-Pva-102767	Pteropus vampyrus	44.40	4.00e-53	201.00
IUUC-Rno-105489	Rattus norvegicus	63.04	5.00e-76	277.00
IUUC-Sha-106912	Sarcophilus harrisii	57.83	4.00e-74	271.00
IUUC-Sar-113338	Sorex araneus	49.32	1.00e-52	199.00
IUUC-Ssc-116027	Sus scrofa	54.00	3.00e-73	268.00
IUUC-Tgu-117049	Taeniopygia guttata	61.30	1.00e-66	246.00
IUUC-Tru-118718	Takifugu rubripes	61.47	1.00e-75	276.00
IUUC-Tni-119931	Tetraodon nigroviridis	57.58	3.00e-71	261.00
IUUC-Xtr-131797	Xenopus tropicalis	62.61	3.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence