iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-063028

UUCD1 version

UUC-MoD-00381

Ensembl Protein ID

ENSMODP00000002143.3

UniProt Accession

F6WZL4; F6WZL4_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001750.3	ENSMODT00000002187.3	ENSMODP00000002143.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.30e-07	30.9	274	315

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e +  kd +++lpC+H+fh++C+  w         + +CP C+
   Q: 274  CAVCIENYkpKDIVRILPCKHIFHRTCIDPW------LLDHRTCPMCK 315
           ******9977666******************......9999******6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVRRRRRWQS DGGGLGSAVV LLALALCELP GARGRALEWY SALVSTVYVD PLTNATVQGA 60
TESGRYGDNS PKESLQGLVG IPRAPGRDRK GCAPDTRYYV PPLGGRTSGR REPWIALVAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTCGTTA AATCGATTTT AAAATTTTAT TCTGAGAAGC CCAGTTCACC AGACTGCAGA 60
GTCCAAGAAA CAAAAGAAAG GTTAAGAACT CCAGCATCAG AACTAATTCT AGGTCGCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

KEGG

mdo:100015936

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000107	Aegilops tauschii	30.30	3.00e-11	62.80
IUUC-Aml-001968	Ailuropoda melanoleuca	77.35	2.00e-157	548.00
IUUC-Apl-004109	Anas platyrhynchos	81.40	5.00e-111	393.00
IUUC-Bta-012340	Bos taurus	70.36	7.00e-149	520.00
IUUC-Cja-019566	Callithrix jacchus	73.44	1.00e-153	536.00
IUUC-Cfa-020289	Canis familiaris	80.52	7.00e-102	362.00
IUUC-Cpo-021916	Cavia porcellus	60.15	1.00e-69	256.00
IUUC-Csa-024084	Chlorocebus sabaeus	73.96	2.00e-149	521.00
IUUC-Cho-024305	Choloepus hoffmanni	76.30	2.00e-123	435.00
IUUC-Cin-025124	Ciona intestinalis	37.97	1.00e-53	202.00
IUUC-Csv-026229	Ciona savignyi	38.27	3.00e-57	215.00
IUUC-Cne-026985	Cryptococcus neoformans	28.57	9.00e-12	66.20
IUUC-Dno-030098	Dasypus novemcinctus	76.36	1.00e-165	575.00
IUUC-Dor-030620	Dipodomys ordii	68.42	5.00e-128	450.00
IUUC-Ete-032306	Echinops telfairi	77.68	2.00e-164	572.00
IUUC-Fca-035950	Felis catus	79.83	6.00e-113	399.00
IUUC-Fal-037429	Ficedula albicollis	76.31	7.00e-155	540.00
IUUC-Fso-038141	Fusarium solani	41.33	4.00e-14	72.80
IUUC-Gga-041201	Gallus gallus	74.20	2.00e-145	508.00
IUUC-Ggo-045429	Gorilla gorilla	73.60	5.00e-146	510.00
IUUC-Hsa-046191	Homo sapiens	70.99	2.00e-151	528.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	70.89	1.00e-134	472.00
IUUC-Lch-049498	Latimeria chalumnae	67.03	5.00e-149	520.00
IUUC-Laf-054239	Loxodonta africana	68.08	9.00e-126	442.00
IUUC-Meu-056382	Macropus eugenii	93.68	0.00e+00	704.00
IUUC-Mga-059435	Meleagris gallopavo	78.33	3.00e-70	257.00
IUUC-Mmr-061513	Microcebus murinus	73.08	4.00e-147	514.00
IUUC-Mmu-063545	Mus musculus	69.81	3.00e-136	478.00
IUUC-Mpu-066370	Mustela putorius furo	73.63	1.00e-153	535.00
IUUC-Mlu-067271	Myotis lucifugus	69.91	1.00e-125	442.00
IUUC-Nle-069207	Nomascus leucogenys	74.86	1.00e-154	539.00
IUUC-Opr-070704	Ochotona princeps	67.08	2.00e-88	318.00
IUUC-Oan-072837	Ornithorhynchus anatinus	75.00	8.00e-168	582.00
IUUC-Ocu-074671	Oryctolagus cuniculus	71.68	6.00e-108	383.00
IUUC-Oga-089083	Otolemur garnettii	73.51	1.00e-151	529.00
IUUC-Oar-089254	Ovis aries	74.36	3.00e-102	364.00
IUUC-Ptr-090940	Pan troglodytes	74.59	4.00e-152	531.00
IUUC-Pan-092636	Papio anubis	73.68	5.00e-149	520.00
IUUC-Psi-093435	Pelodiscus sinensis	80.85	2.00e-106	378.00
IUUC-Pab-098525	Pongo abelii	74.73	2.00e-152	532.00
IUUC-Pva-102395	Pteropus vampyrus	70.92	5.00e-157	546.00
IUUC-Ptt-103733	Puccinia triticina	45.10	1.00e-09	57.40
IUUC-Rno-105789	Rattus norvegicus	71.35	3.00e-136	478.00
IUUC-Sha-107305	Sarcophilus harrisii	91.91	3.00e-128	450.00
IUUC-Ssc-115598	Sus scrofa	72.58	5.00e-147	513.00
IUUC-Tgu-116463	Taeniopygia guttata	75.78	1.00e-148	518.00
IUUC-Tsy-118915	Tarsius syrichta	74.79	4.00e-94	337.00
IUUC-Tme-126970	Tuber melanosporum	47.17	2.00e-12	67.40
IUUC-Tbe-127906	Tupaia belangeri	78.95	2.00e-75	275.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence