iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059451

UUCD1 version

UUC-MeG-00117

Ensembl Protein ID

ENSMGAP00000001954.1

UniProt Accession

G1MU07; G1MU07_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002375.1	ENSMGAT00000002625.1	ENSMGAP00000001954.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.30e-26	90.5	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.20e-08	33.3	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+v+g+ef++h++vLaa+S++F+a+fl+++eesk k +v ++dv+p+v+  +l+++Yt++l+++e
   Q: 34   DCVLKVKGKEFPCHRLVLAACSPYFRAMFLSDMEESK-KREVSLEDVDPDVMGKILHYIYTSELEITE 100
           9************************************.*************************99865 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+Ncl+i+r++ ++dc +L+ aa+dfi++ F
   Q: 132  LSNCLAIFRLGLMLDCARLAVAARDFICDRF 162
           69***************************99 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MGLPFDQAEE LRLYQQTLLQ DGLKDMLDHN KFLDCVLKVK GKEFPCHRLV LAACSPYFRA 60
MFLSDMEESK KREVSLEDVD PDVMGKILHY IYTSELEITE QNVQDIFSVA NMFQIPSIFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTTTGC CTTTTGATCA AGCGGAAGAA CTGCGTCTCT ACCAGCAAAC CCTCCTCCAG 60
GATGGACTCA AAGACATGTT GGACCACAAT AAGTTTCTGG ACTGTGTCTT GAAAGTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

KEGG

mgp:100551211

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	68.05	0.00e+00	843.00
IUUC-Apl-003748	Anas platyrhynchos	96.61	0.00e+00	1152.00
IUUC-Aca-005275	Anolis carolinensis	79.33	0.00e+00	971.00
IUUC-Ath-007591	Arabidopsis thaliana	30.58	9.00e-14	71.20
IUUC-Ame-011294	Astyanax mexicanus	64.52	0.00e+00	797.00
IUUC-Bta-012801	Bos taurus	71.09	0.00e+00	910.00
IUUC-Bdi-014457	Brachypodium distachyon	25.11	1.00e-11	63.90
IUUC-Cja-019795	Callithrix jacchus	70.82	0.00e+00	823.00
IUUC-Cfa-020782	Canis familiaris	57.03	0.00e+00	709.00
IUUC-Cpo-022436	Cavia porcellus	69.77	0.00e+00	908.00
IUUC-Cre-022652	Chlamydomonas reinhardtii	33.33	8.00e-11	60.50
IUUC-Csa-023105	Chlorocebus sabaeus	71.59	0.00e+00	917.00
IUUC-Cin-025237	Ciona intestinalis	27.60	3.00e-65	242.00
IUUC-Dre-028603	Danio rerio	64.24	0.00e+00	816.00
IUUC-Dno-029516	Dasypus novemcinctus	56.05	0.00e+00	700.00
IUUC-Dor-030850	Dipodomys ordii	53.07	1.00e-120	426.00
IUUC-Ete-032697	Echinops telfairi	56.70	0.00e+00	700.00
IUUC-Eca-034393	Equus caballus	70.69	0.00e+00	849.00
IUUC-Eeu-035245	Erinaceus europaeus	57.74	0.00e+00	654.00
IUUC-Fca-035823	Felis catus	61.69	0.00e+00	768.00
IUUC-Fal-037632	Ficedula albicollis	94.35	0.00e+00	1114.00
IUUC-Gmo-039697	Gadus morhua	61.35	0.00e+00	777.00
IUUC-Gga-040525	Gallus gallus	99.03	0.00e+00	1190.00
IUUC-Gac-042421	Gasterosteus aculeatus	66.29	0.00e+00	832.00
IUUC-Gma-043151	Glycine max	29.44	6.00e-15	75.10
IUUC-Ggo-045596	Gorilla gorilla	71.91	0.00e+00	914.00
IUUC-Hsa-046235	Homo sapiens	71.75	0.00e+00	909.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	72.57	0.00e+00	925.00
IUUC-Lch-050123	Latimeria chalumnae	71.64	0.00e+00	915.00
IUUC-Loc-051824	Lepisosteus oculatus	70.28	0.00e+00	882.00
IUUC-Laf-053500	Loxodonta africana	56.37	0.00e+00	704.00
IUUC-Mcc-054909	Macaca mulatta	71.27	0.00e+00	917.00
IUUC-Meu-055972	Macropus eugenii	71.63	0.00e+00	911.00
IUUC-Mmr-060736	Microcebus murinus	71.70	0.00e+00	914.00
IUUC-Mdo-062563	Monodelphis domestica	72.73	0.00e+00	729.00
IUUC-Mmu-063549	Mus musculus	71.79	0.00e+00	914.00
IUUC-Mpu-066262	Mustela putorius furo	72.68	0.00e+00	927.00
IUUC-Mlu-067210	Myotis lucifugus	72.32	0.00e+00	916.00
IUUC-Nle-069339	Nomascus leucogenys	56.86	0.00e+00	707.00
IUUC-Opr-070384	Ochotona princeps	67.84	0.00e+00	842.00
IUUC-Ont-071273	Oreochromis niloticus	66.29	0.00e+00	834.00
IUUC-Oan-073476	Ornithorhynchus anatinus	56.70	0.00e+00	708.00
IUUC-Ocu-074499	Oryctolagus cuniculus	71.70	0.00e+00	917.00
IUUC-Ola-087175	Oryzias latipes	64.09	0.00e+00	800.00
IUUC-Oga-088855	Otolemur garnettii	71.70	0.00e+00	914.00
IUUC-Oar-090349	Ovis aries	57.03	0.00e+00	706.00
IUUC-Ptr-091028	Pan troglodytes	68.11	3.00e-178	617.00
IUUC-Pan-091827	Papio anubis	71.43	0.00e+00	917.00
IUUC-Psi-092998	Pelodiscus sinensis	88.69	0.00e+00	1069.00
IUUC-Pma-094586	Petromyzon marinus	63.35	6.00e-102	363.00
IUUC-Pfo-096216	Poecilia formosa	64.19	0.00e+00	823.00
IUUC-Pab-098711	Pongo abelii	56.70	0.00e+00	704.00
IUUC-Pca-100495	Procavia capensis	51.63	0.00e+00	628.00
IUUC-Pva-102331	Pteropus vampyrus	65.02	0.00e+00	818.00
IUUC-Pte-104106	Pyrenophora teres	29.56	8.00e-11	60.10
IUUC-Rno-105613	Rattus norvegicus	70.13	0.00e+00	793.00
IUUC-Sha-107091	Sarcophilus harrisii	73.23	0.00e+00	955.00
IUUC-Sar-113405	Sorex araneus	56.21	0.00e+00	687.00
IUUC-Ssc-116276	Sus scrofa	71.25	0.00e+00	913.00
IUUC-Tgu-116494	Taeniopygia guttata	94.67	0.00e+00	1147.00
IUUC-Tru-118614	Takifugu rubripes	65.97	0.00e+00	836.00
IUUC-Tsy-119225	Tarsius syrichta	53.43	0.00e+00	639.00
IUUC-Tni-119776	Tetraodon nigroviridis	65.32	0.00e+00	832.00
IUUC-Tbe-127806	Tupaia belangeri	66.51	0.00e+00	839.00
IUUC-Ttr-128813	Tursiops truncatus	71.04	0.00e+00	902.00
IUUC-Vpa-130714	Vicugna pacos	56.70	0.00e+00	708.00
IUUC-Xtr-132942	Xenopus tropicalis	76.58	0.00e+00	955.00
IUUC-Xma-133573	Xiphophorus maculatus	64.15	0.00e+00	809.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence