iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006790

UUCD1 version

UUC-ArT-00775

Ensembl Protein ID

AT2G25490.1

UniProt Accession

Q9SKK0; B9DHK7; Q0WM37; EBF1_ARATH

Genbank Protein ID

CAE75864.1; AAD20708.1; AEC07708.1; AAL60026.1; AAM14272.1; BAH20224.1; BAF01819.1

Protein Name

EIN3-binding F-box protein 1; F-box/LRR-repeat protein 6

Genbank Nucleotide ID

AJ609238; AC006300; CP002685; AY072205; AY091333; AK317560; AK229995

Gene Name

EBF1; FBL6; At2g25490; F13B15.15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G25490	AT2G25490.1	AT2G25490.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	17220175

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.01	16.8	50	100

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 89   aptptpeegpdaglldrlpeeilveilklldkee.llraarvcrrwqelas 138
           apt     + +  ++d lp+e+l+ei+++l++++   ++a v+++w +l s
   Q: 50   APTIFSAFEKKPVSIDVLPDECLFEIFRRLSGPQeRSACAFVSKQWLTLVS 100
           566666667778899***************777769**********97766 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of SCF(EBF1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (probably including EIN3 and EIL1). Regulator of the ethylene signaling cascade by modulating the stability of EIN3 and EIL1 proteins. Confers insensitivity to ethylene.

Protein Sequence
(Fasta)

MSQIFSFAGE NDFYRRGAIY PNPKDASLLL SLGSFADVYF PPSKRSRVVA PTIFSAFEKK 60
PVSIDVLPDE CLFEIFRRLS GPQERSACAF VSKQWLTLVS SIRQKEIDVP SKITEDGDDC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAAAGAGT AAGGTTGTTC CAGGAACCAA ACAAAAACAA TTTAATACTA TAACTAAACT 60
CGGTAACCAA ACACCTCATA ACTTGCCTTA ACGCGCTCTC AAAGGTGAAA AAAAACTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0936--Ethylene signaling pathway
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005634--C:nucleus
GO:0009873--P:ethylene-activated signaling pathway
GO:0010105--P:negative regulation of ethylene-activated signaling pathway
GO:0016567--P:protein ubiquitination
GO:0009723--P:response to ethylene
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT2G25490

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000881	Aegilops tauschii	48.89	2.00e-151	529.00
IUUC-Atr-002552	Amborella trichopoda	50.77	2.00e-174	605.00
IUUC-Aly-006311	Arabidopsis lyrata	94.91	0.00e+00	1174.00
IUUC-Bdi-014596	Brachypodium distachyon	48.98	9.00e-155	540.00
IUUC-Bol-015153	Brassica oleracea	84.60	0.00e+00	1043.00
IUUC-Bra-017379	Brassica rapa	84.52	0.00e+00	1019.00
IUUC-Cja-019300	Callithrix jacchus	26.29	9.00e-28	117.00
IUUC-Cfa-021192	Canis familiaris	25.67	2.00e-34	140.00
IUUC-Cpo-022482	Cavia porcellus	24.86	3.00e-31	129.00
IUUC-Cin-025793	Ciona intestinalis	24.28	6.00e-32	132.00
IUUC-Csv-026303	Ciona savignyi	24.34	4.00e-28	119.00
IUUC-Fca-035625	Felis catus	24.82	3.00e-27	116.00
IUUC-Gma-042946	Glycine max	62.11	0.00e+00	786.00
IUUC-Hvu-047403	Hordeum vulgare	49.33	2.00e-140	491.00
IUUC-Lpe-051075	Leersia perrieri	47.97	2.00e-151	528.00
IUUC-Mtr-057658	Medicago truncatula	60.00	0.00e+00	743.00
IUUC-Mmr-061592	Microcebus murinus	24.50	1.00e-29	124.00
IUUC-Mac-065656	Musa acuminata	49.54	7.00e-172	596.00
IUUC-Mlu-067940	Myotis lucifugus	25.10	1.00e-27	117.00
IUUC-Ocu-073848	Oryctolagus cuniculus	25.95	1.00e-31	130.00
IUUC-Oba-075482	Oryza barthii	46.23	1.00e-152	532.00
IUUC-Obr-076655	Oryza brachyantha	49.12	2.00e-127	448.00
IUUC-Ogl-077627	Oryza glaberrima	46.40	2.00e-153	535.00
IUUC-Ogu-078848	Oryza glumaepatula	46.23	8.00e-153	533.00
IUUC-Oin-079776	Oryza indica	46.23	2.00e-152	531.00
IUUC-Olo-080728	Oryza longistaminata	48.26	7.00e-127	446.00
IUUC-Ome-081750	Oryza meridionalis	47.03	4.00e-154	537.00
IUUC-Oni-082957	Oryza nivara	46.73	8.00e-153	533.00
IUUC-Opu-083568	Oryza punctata	47.03	9.00e-150	523.00
IUUC-Oru-084584	Oryza rufipogon	46.31	5.00e-151	527.00
IUUC-Osa-085423	Oryza sativa	46.31	5.00e-151	527.00
IUUC-Oga-089110	Otolemur garnettii	26.59	1.00e-30	127.00
IUUC-Pma-094494	Petromyzon marinus	29.85	2.00e-30	125.00
IUUC-Ppa-095810	Physcomitrella patens	36.40	6.00e-76	278.00
IUUC-Pab-098377	Pongo abelii	25.68	6.00e-31	128.00
IUUC-Pop-098975	Populus trichocarpa	64.65	0.00e+00	820.00
IUUC-Ppe-101207	Prunus persica	62.13	0.00e+00	790.00
IUUC-Pva-102941	Pteropus vampyrus	25.00	1.00e-30	127.00
IUUC-Sha-107390	Sarcophilus harrisii	25.80	5.00e-27	115.00
IUUC-Spo-108035	Schizosaccharomyces pombe	24.70	7.00e-10	58.20
IUUC-Smo-109612	Selaginella moellendorffii	37.50	1.00e-101	363.00
IUUC-Sit-110627	Setaria italica	48.90	1.00e-160	558.00
IUUC-Sly-111002	Solanum lycopersicum	55.90	0.00e+00	731.00
IUUC-Stu-112036	Solanum tuberosum	56.65	0.00e+00	748.00
IUUC-Sbi-114535	Sorghum bicolor	49.49	4.00e-159	554.00
IUUC-Tsy-119620	Tarsius syrichta	26.47	5.00e-30	125.00
IUUC-Tca-121078	Theobroma cacao	63.88	0.00e+00	766.00
IUUC-Tae-125289	Triticum aestivum	48.44	1.00e-148	519.00
IUUC-Tur-126530	Triticum urartu	49.15	1.00e-124	439.00
IUUC-Tbe-128120	Tupaia belangeri	26.08	7.00e-26	111.00
IUUC-Vvi-131401	Vitis vinifera	59.61	0.00e+00	689.00
IUUC-Xtr-132187	Xenopus tropicalis	27.17	3.00e-30	125.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence