iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059217

Ensembl Protein ID

ENSMGAP00000016461.2

UniProt Accession

G1NR84; G1NR84_MELGA

Protein Name

Inhibitor of growth protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000015516.2	ENSMGAT00000017435.2	ENSMGAP00000016461.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.70e-09	36.8	187	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 187  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 234
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MDSPGKKKLS QLPPNSYLFS YKILKDLDDY YEKFKRENDA VQKRRMLHCI QRALIRSQEL 60
GDEKIQIVSQ MVELVENRSR QVDSHVELFE TCQETNDTTG NSGKANQDKS KNETITQSEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTCAC CTGGGAAAAA GGAAAGCTGT GAGCAGAACG ATGGCAGGGG TGTCTGTGAA 60
GCCAAGTCCT CGTGAGTTAG GATGGCTGAG TGTGTGTGAG TACCACAGTA AAACTCCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	92.27	5.00e-101	360.00
IUUC-Apl-003910	Anas platyrhynchos	97.42	2.00e-107	381.00
IUUC-Aca-004874	Anolis carolinensis	95.28	3.00e-104	370.00
IUUC-Ame-011262	Astyanax mexicanus	65.57	2.00e-75	274.00
IUUC-Bta-013507	Bos taurus	87.55	1.00e-90	325.00
IUUC-Cja-018925	Callithrix jacchus	87.12	4.00e-94	337.00
IUUC-Cfa-020947	Canis familiaris	92.27	2.00e-100	357.00
IUUC-Cpo-022286	Cavia porcellus	88.33	5.00e-98	350.00
IUUC-Csa-023825	Chlorocebus sabaeus	86.70	1.00e-93	335.00
IUUC-Cho-024577	Choloepus hoffmanni	92.67	3.00e-99	353.00
IUUC-Cne-027005	Cryptococcus neoformans	47.76	1.00e-15	77.00
IUUC-Dno-029834	Dasypus novemcinctus	93.13	2.00e-101	361.00
IUUC-Dor-030315	Dipodomys ordii	89.27	7.00e-108	383.00
IUUC-Ete-032408	Echinops telfairi	84.25	9.00e-96	343.00
IUUC-Eca-034244	Equus caballus	92.27	5.00e-101	359.00
IUUC-Fca-035391	Felis catus	89.91	3.00e-92	330.00
IUUC-Fal-036838	Ficedula albicollis	96.57	2.00e-106	378.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	2.00e-19	89.70
IUUC-Gga-040619	Gallus gallus	98.71	1.00e-108	385.00
IUUC-Gac-041996	Gasterosteus aculeatus	61.44	2.00e-75	275.00
IUUC-Ggo-045481	Gorilla gorilla	86.70	6.00e-94	337.00
IUUC-Hsa-046170	Homo sapiens	86.70	4.00e-94	337.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	94.42	2.00e-102	363.00
IUUC-Lch-050397	Latimeria chalumnae	88.84	2.00e-98	351.00
IUUC-Loc-052038	Lepisosteus oculatus	80.37	4.00e-82	296.00
IUUC-Laf-054126	Loxodonta africana	93.56	6.00e-102	363.00
IUUC-Mcc-055031	Macaca mulatta	86.70	4.00e-94	337.00
IUUC-Meu-056248	Macropus eugenii	93.36	2.00e-104	371.00
IUUC-Mmr-061581	Microcebus murinus	93.56	1.00e-101	361.00
IUUC-Mdo-062452	Monodelphis domestica	94.42	8.00e-104	369.00
IUUC-Mmu-063412	Mus musculus	91.42	6.00e-99	353.00
IUUC-Mpu-066479	Mustela putorius furo	92.27	5.00e-101	360.00
IUUC-Mlu-067723	Myotis lucifugus	92.70	5.00e-101	359.00
IUUC-Nle-069122	Nomascus leucogenys	86.27	4.00e-93	333.00
IUUC-Opr-070835	Ochotona princeps	83.62	3.00e-83	300.00
IUUC-Ont-071606	Oreochromis niloticus	57.75	6.00e-70	256.00
IUUC-Oan-073023	Ornithorhynchus anatinus	91.38	5.00e-97	346.00
IUUC-Ocu-073779	Oryctolagus cuniculus	89.27	9.00e-93	332.00
IUUC-Ola-086891	Oryzias latipes	63.36	2.00e-76	278.00
IUUC-Oga-087954	Otolemur garnettii	90.99	4.00e-99	353.00
IUUC-Oar-090006	Ovis aries	87.55	9.00e-95	339.00
IUUC-Ptr-090589	Pan troglodytes	86.70	1.00e-93	335.00
IUUC-Pan-091896	Papio anubis	86.70	3.00e-94	338.00
IUUC-Psi-093266	Pelodiscus sinensis	95.71	2.00e-105	374.00
IUUC-Pma-094265	Petromyzon marinus	71.95	2.00e-34	137.00
IUUC-Pfo-097531	Poecilia formosa	59.69	5.00e-74	270.00
IUUC-Pab-098253	Pongo abelii	86.70	2.00e-93	335.00
IUUC-Pva-102753	Pteropus vampyrus	88.41	1.00e-89	322.00
IUUC-Rno-105964	Rattus norvegicus	90.99	8.00e-90	322.00
IUUC-Sha-107270	Sarcophilus harrisii	94.42	4.00e-103	367.00
IUUC-Tgu-116822	Taeniopygia guttata	97.00	7.00e-107	379.00
IUUC-Tru-118262	Takifugu rubripes	54.62	2.00e-66	244.00
IUUC-Tni-119980	Tetraodon nigroviridis	58.08	8.00e-73	266.00
IUUC-Tvi-122341	Trichoderma virens	62.50	4.00e-16	76.60
IUUC-Ttr-128672	Tursiops truncatus	89.70	2.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence