iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001782

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01004307

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000009634.1	ENSAMET00000010568.1	ENSAMEP00000010127.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.10e-09	38.6	2	45
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.10e-08	32.9	60	88

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 22   sSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +S++F+a+f ++l+es+  ++v +++v p+ ++ ll+F+Ytg++ 
   Q: 2    ASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDFSYTGRVV 45
           69***************.************************985 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c  L++aa++fil+h
   Q: 60   ANCLDMQDFAEAFSCAGLASAAQRFILRH 88
           6***************************9 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

XASPYFRAMF AGQLRESRAE RVRLHGVPPD MLQLLLDFSY TGRVVKEACG AFLQQQLDLA 60
NCLDMQDFAE AFSCAGLASA AQRFILRHVG ELGPEQLERL PLARLLRYLR DDGLCVPKEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NCCGCCAGCC CCTACTTCCG CGCCATGTTC GCGGGGCAGC TGCGCGAGAG CCGCGCCGAG 60
CGGGTGCGCC TGCATGGCGT GCCGCCCGAC ATGCTGCAGC TGCTGCTCGA CTTCAGCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF01344--Kelch_1

SMART

SM00875--BACK
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003189	Anas platyrhynchos	81.75	2.00e-140	491.00
IUUC-Ame-011774	Astyanax mexicanus	58.72	2.00e-94	338.00
IUUC-Bta-012367	Bos taurus	89.46	0.00e+00	943.00
IUUC-Cja-019501	Callithrix jacchus	84.22	0.00e+00	881.00
IUUC-Cfa-020550	Canis familiaris	90.94	0.00e+00	961.00
IUUC-Cpo-022072	Cavia porcellus	86.88	0.00e+00	901.00
IUUC-Csa-023364	Chlorocebus sabaeus	88.20	0.00e+00	893.00
IUUC-Cin-025253	Ciona intestinalis	40.79	1.00e-116	413.00
IUUC-Csv-025871	Ciona savignyi	41.30	1.00e-119	423.00
IUUC-Dre-028694	Danio rerio	68.81	0.00e+00	718.00
IUUC-Dno-029082	Dasypus novemcinctus	84.96	0.00e+00	839.00
IUUC-Dor-030680	Dipodomys ordii	87.80	0.00e+00	926.00
IUUC-Ete-032315	Echinops telfairi	85.97	0.00e+00	845.00
IUUC-Eca-033570	Equus caballus	97.90	0.00e+00	676.00
IUUC-Eeu-035067	Erinaceus europaeus	95.31	1.00e-147	516.00
IUUC-Fca-035663	Felis catus	96.17	7.00e-133	465.00
IUUC-Fal-037103	Ficedula albicollis	76.19	0.00e+00	734.00
IUUC-Gmo-039420	Gadus morhua	65.96	0.00e+00	692.00
IUUC-Gga-040161	Gallus gallus	74.35	0.00e+00	712.00
IUUC-Gac-041755	Gasterosteus aculeatus	68.08	0.00e+00	720.00
IUUC-Ggo-044899	Gorilla gorilla	87.99	0.00e+00	909.00
IUUC-Hsa-045834	Homo sapiens	88.17	0.00e+00	905.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	87.62	0.00e+00	924.00
IUUC-Lch-050338	Latimeria chalumnae	65.50	0.00e+00	725.00
IUUC-Loc-051780	Lepisosteus oculatus	70.82	0.00e+00	735.00
IUUC-Laf-053725	Loxodonta africana	78.46	0.00e+00	797.00
IUUC-Mcc-055032	Macaca mulatta	88.06	0.00e+00	754.00
IUUC-Meu-056661	Macropus eugenii	87.34	0.00e+00	695.00
IUUC-Mga-059821	Meleagris gallopavo	81.71	1.00e-125	442.00
IUUC-Mdo-062095	Monodelphis domestica	84.00	0.00e+00	734.00
IUUC-Mmu-063138	Mus musculus	87.43	0.00e+00	925.00
IUUC-Mpu-066386	Mustela putorius furo	98.76	0.00e+00	662.00
IUUC-Mlu-067807	Myotis lucifugus	95.51	0.00e+00	661.00
IUUC-Nle-069181	Nomascus leucogenys	87.25	0.00e+00	912.00
IUUC-Opr-070658	Ochotona princeps	87.62	0.00e+00	956.00
IUUC-Ont-072209	Oreochromis niloticus	67.70	0.00e+00	708.00
IUUC-Oan-072861	Ornithorhynchus anatinus	90.23	8.00e-118	415.00
IUUC-Ocu-074631	Oryctolagus cuniculus	86.32	0.00e+00	856.00
IUUC-Ola-087553	Oryzias latipes	66.67	0.00e+00	697.00
IUUC-Oga-088782	Otolemur garnettii	87.80	0.00e+00	928.00
IUUC-Oar-089634	Ovis aries	89.28	0.00e+00	942.00
IUUC-Ptr-091259	Pan troglodytes	90.58	0.00e+00	771.00
IUUC-Pan-091734	Papio anubis	88.35	0.00e+00	912.00
IUUC-Psi-092979	Pelodiscus sinensis	75.91	0.00e+00	767.00
IUUC-Pma-094459	Petromyzon marinus	54.80	5.00e-78	285.00
IUUC-Pfo-097446	Poecilia formosa	67.70	0.00e+00	707.00
IUUC-Pab-098765	Pongo abelii	88.17	0.00e+00	930.00
IUUC-Pva-102730	Pteropus vampyrus	85.03	0.00e+00	884.00
IUUC-Rno-104972	Rattus norvegicus	87.06	0.00e+00	924.00
IUUC-Ssc-115869	Sus scrofa	87.92	0.00e+00	757.00
IUUC-Tgu-116562	Taeniopygia guttata	76.00	0.00e+00	775.00
IUUC-Tru-118490	Takifugu rubripes	67.32	0.00e+00	704.00
IUUC-Tni-119898	Tetraodon nigroviridis	66.54	0.00e+00	694.00
IUUC-Ttr-128976	Tursiops truncatus	96.48	2.00e-148	519.00
IUUC-Xtr-132876	Xenopus tropicalis	69.87	0.00e+00	749.00
IUUC-Xma-133540	Xiphophorus maculatus	68.48	0.00e+00	713.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence