iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004214

Ensembl Protein ID

ENSAPLP00000011206.1

UniProt Accession

U3IVD3; U3IVD3_ANAPL

Genbank Protein ID

ENSAPLP00000011206

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01079499

Gene Name

RNF139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011464.1	ENSAPLT00000011929.1	ENSAPLP00000011206.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.90e-09	35.3	491	529

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+ +f +  +++pC+H fha Cl kw       + +++CP C
   Q: 491  CAICYHEFTTSARITPCNHYFHALCLRKW------LYIQDTCPMC 529
           ********999******************......********** PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LSGVFVSSVV LVLQQRALFK FYMIASAFLL AATSVLVNYY ASLHINFYSA YYTAAFGIQF 60
LPHKGPSLWM ALSILQLTFG IGYVTLLNVQ SIYSQLIILD ILIPVIGLVV ELPVSVRQVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCAGGTG TCTTTGTGTC CAGTGTTGTT CTGGTGTTAC AACAGCGAGC ACTTTTCAAG 60
TTCTACATGA TCGCCTCGGC GTTCCTGCTG GCTGCAACTT CAGTGTTGGT GAATTACTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0036503--P:ERAD pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0017148--P:negative regulation of translation
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031648--P:protein destabilization
GO:0060628--P:regulation of ER to Golgi vesicle-mediated transport
GO:0070613--P:regulation of protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	85.85	0.00e+00	949.00
IUUC-Aca-005326	Anolis carolinensis	87.01	0.00e+00	981.00
IUUC-Ame-011687	Astyanax mexicanus	77.32	0.00e+00	833.00
IUUC-Bta-013394	Bos taurus	86.03	0.00e+00	969.00
IUUC-Bci-013813	Botrytis cinerea	40.35	2.00e-07	49.70
IUUC-Cja-019499	Callithrix jacchus	84.40	0.00e+00	973.00
IUUC-Cfa-020357	Canis familiaris	86.42	0.00e+00	952.00
IUUC-Cpo-021924	Cavia porcellus	85.11	0.00e+00	988.00
IUUC-Csa-023513	Chlorocebus sabaeus	85.87	0.00e+00	965.00
IUUC-Cho-024285	Choloepus hoffmanni	79.04	0.00e+00	823.00
IUUC-Cin-025223	Ciona intestinalis	53.18	1.00e-73	268.00
IUUC-Csv-026018	Ciona savignyi	47.62	1.00e-65	242.00
IUUC-Dre-028660	Danio rerio	75.09	0.00e+00	754.00
IUUC-Dno-029463	Dasypus novemcinctus	92.23	6.00e-111	394.00
IUUC-Dor-030728	Dipodomys ordii	86.03	0.00e+00	957.00
IUUC-Dme-032186	Drosophila melanogaster	43.86	2.00e-99	357.00
IUUC-Ete-032368	Echinops telfairi	82.94	0.00e+00	964.00
IUUC-Eca-034325	Equus caballus	85.69	0.00e+00	946.00
IUUC-Fca-035537	Felis catus	86.42	0.00e+00	949.00
IUUC-Fal-037459	Ficedula albicollis	91.30	0.00e+00	1045.00
IUUC-Fso-038284	Fusarium solani	32.10	5.00e-08	52.80
IUUC-Gmo-039442	Gadus morhua	77.99	8.00e-99	354.00
IUUC-Gga-041071	Gallus gallus	95.12	0.00e+00	1051.00
IUUC-Gac-042483	Gasterosteus aculeatus	74.50	0.00e+00	863.00
IUUC-Ggo-044672	Gorilla gorilla	85.87	0.00e+00	964.00
IUUC-Hsa-045836	Homo sapiens	85.66	0.00e+00	938.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	86.11	0.00e+00	985.00
IUUC-Lch-050073	Latimeria chalumnae	80.33	0.00e+00	925.00
IUUC-Loc-052908	Lepisosteus oculatus	81.07	0.00e+00	912.00
IUUC-Laf-053519	Loxodonta africana	84.40	0.00e+00	979.00
IUUC-Mga-059922	Meleagris gallopavo	91.75	0.00e+00	1036.00
IUUC-Mmr-061452	Microcebus murinus	85.69	0.00e+00	964.00
IUUC-Mdo-062412	Monodelphis domestica	87.68	0.00e+00	979.00
IUUC-Mmu-063147	Mus musculus	84.40	0.00e+00	978.00
IUUC-Mpu-065929	Mustela putorius furo	86.21	0.00e+00	950.00
IUUC-Mlu-067899	Myotis lucifugus	83.73	0.00e+00	949.00
IUUC-Nle-070083	Nomascus leucogenys	85.87	0.00e+00	965.00
IUUC-Opr-070461	Ochotona princeps	82.75	0.00e+00	955.00
IUUC-Ont-072256	Oreochromis niloticus	74.45	0.00e+00	860.00
IUUC-Oan-073150	Ornithorhynchus anatinus	85.32	0.00e+00	904.00
IUUC-Ocu-073748	Oryctolagus cuniculus	84.26	0.00e+00	938.00
IUUC-Oga-088565	Otolemur garnettii	86.24	0.00e+00	969.00
IUUC-Oar-089432	Ovis aries	85.69	0.00e+00	991.00
IUUC-Ptr-091422	Pan troglodytes	85.87	0.00e+00	965.00
IUUC-Pan-092331	Papio anubis	85.87	0.00e+00	965.00
IUUC-Psi-092933	Pelodiscus sinensis	89.56	0.00e+00	1003.00
IUUC-Pfo-097466	Poecilia formosa	72.76	0.00e+00	860.00
IUUC-Pab-098702	Pongo abelii	85.87	0.00e+00	964.00
IUUC-Pca-100125	Procavia capensis	84.35	0.00e+00	969.00
IUUC-Pva-102628	Pteropus vampyrus	85.85	0.00e+00	949.00
IUUC-Rno-104886	Rattus norvegicus	85.48	0.00e+00	984.00
IUUC-Sha-106702	Sarcophilus harrisii	87.50	0.00e+00	978.00
IUUC-Ssc-115482	Sus scrofa	86.06	0.00e+00	977.00
IUUC-Tgu-116829	Taeniopygia guttata	91.68	0.00e+00	1057.00
IUUC-Tru-118557	Takifugu rubripes	75.14	0.00e+00	835.00
IUUC-Tsy-119399	Tarsius syrichta	79.40	7.00e-173	599.00
IUUC-Tni-120006	Tetraodon nigroviridis	66.73	0.00e+00	689.00
IUUC-Tbe-127664	Tupaia belangeri	84.77	0.00e+00	950.00
IUUC-Ttr-129144	Tursiops truncatus	86.06	0.00e+00	997.00
IUUC-Vpa-130226	Vicugna pacos	86.06	0.00e+00	969.00
IUUC-Vvi-131278	Vitis vinifera	42.59	1.00e-10	58.90
IUUC-Xtr-132461	Xenopus tropicalis	79.30	0.00e+00	884.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence