iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011434

Ensembl Protein ID

ENSAMXP00000008821.1

UniProt Accession

W5KMK9; W5KMK9_ASTMX

Genbank Protein ID

ENSAMXP00000008821

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01010029

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000008586.1	ENSAMXT00000008821.1	ENSAMXP00000008821.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	6.80e-52	176.9	198	398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cll+++ ++++ +++C+h+ C +Cl+qyl+++i+e++ ++iscp  ec+e++++++i+ +l ++ l+++ye+++l++++ ad++++w
   Q: 198  CPLCLLRHTRDRFPDIMTCHHRSCADCLRQYLRIEISESR-VNISCP--ECSERFNPHDIRMILGDRVLMEKYEEFMLRRWLVADPDCRW 284
           ****************************************.9*****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek.......eeaeskelleanskkCpkCkvyi 171
           cpapdC ++v++  +a  +k ++ +++cg+efC++Ck+ wH++++C+++++++a++ + +       + ++++ ++++++k+Cp+C +yi
   Q: 285  CPAPDCGYAVIAFGCAscPKITCGRDGCGTEFCYHCKQLWHPNQTCDAARQQRAQSLRLRpfrssslSYSQESGAAADDIKPCPRCAAYI 374
           *************99988999999*********************************9999****9999999****************** PP
   S: 172  ek..negCnhmtCakCkaefCwlC 193
           +k  +++CnhmtCa C++efCwlC
   Q: 375  IKmnDGSCNHMTCAVCGCEFCWLC 398
           *997889***************** PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MKCCYVGDSK GAAESQADSE LPHLAQSEPP GSGDRIPGGS SPCHNTLQSP AKTLSPPPPL 60
SPPSPSSSSS SSSFPDLPEV PQPSHSIPSG EMSLNHQPQG SERDLPSAAS SVSLPSVRKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTTTAGAT GGTGAATTTG GAAGGGGCCG AAGGGAGAGG GAGAGAGAGA GAGAGAGAGG 60
CGGTTACAGT GACTCAGAGA GAGAGAGAGA GAGAGAGAGA GAGGCGGTTA CAGTGACTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001958	Ailuropoda melanoleuca	73.76	0.00e+00	926.00
IUUC-Apl-003427	Anas platyrhynchos	75.09	0.00e+00	906.00
IUUC-Aca-004252	Anolis carolinensis	74.43	0.00e+00	897.00
IUUC-Bta-013558	Bos taurus	73.67	0.00e+00	924.00
IUUC-Cel-018626	Caenorhabditis elegans	56.29	6.00e-108	385.00
IUUC-Cja-019070	Callithrix jacchus	74.48	0.00e+00	928.00
IUUC-Cfa-020286	Canis familiaris	73.76	0.00e+00	924.00
IUUC-Cpo-022015	Cavia porcellus	74.48	0.00e+00	925.00
IUUC-Csa-023975	Chlorocebus sabaeus	74.24	0.00e+00	912.00
IUUC-Cho-024442	Choloepus hoffmanni	61.94	0.00e+00	730.00
IUUC-Dre-028422	Danio rerio	84.04	0.00e+00	1062.00
IUUC-Dno-029018	Dasypus novemcinctus	74.43	0.00e+00	909.00
IUUC-Dor-030548	Dipodomys ordii	70.67	4.00e-115	409.00
IUUC-Eca-034249	Equus caballus	73.88	0.00e+00	928.00
IUUC-Eeu-035298	Erinaceus europaeus	82.79	0.00e+00	642.00
IUUC-Fca-035912	Felis catus	73.64	0.00e+00	925.00
IUUC-Fal-037488	Ficedula albicollis	73.49	0.00e+00	871.00
IUUC-Gmo-038893	Gadus morhua	83.69	0.00e+00	800.00
IUUC-Gga-040380	Gallus gallus	74.18	0.00e+00	884.00
IUUC-Gac-041421	Gasterosteus aculeatus	76.14	0.00e+00	837.00
IUUC-Ggo-044893	Gorilla gorilla	74.33	0.00e+00	929.00
IUUC-Hsa-046876	Homo sapiens	74.33	0.00e+00	929.00
IUUC-Itr-048257	Ictidomys tridecemlineatus	73.97	0.00e+00	922.00
IUUC-Lch-049774	Latimeria chalumnae	74.14	0.00e+00	949.00
IUUC-Loc-052040	Lepisosteus oculatus	77.02	0.00e+00	979.00
IUUC-Laf-053874	Loxodonta africana	74.42	0.00e+00	910.00
IUUC-Mcc-054817	Macaca mulatta	68.16	5.00e-58	217.00
IUUC-Mga-060175	Meleagris gallopavo	73.92	0.00e+00	896.00
IUUC-Mmr-060800	Microcebus murinus	74.36	0.00e+00	927.00
IUUC-Mdo-061827	Monodelphis domestica	72.79	0.00e+00	868.00
IUUC-Mmu-064134	Mus musculus	78.38	0.00e+00	898.00
IUUC-Mpu-066076	Mustela putorius furo	74.37	0.00e+00	924.00
IUUC-Mlu-068218	Myotis lucifugus	73.56	0.00e+00	895.00
IUUC-Nle-069707	Nomascus leucogenys	83.99	0.00e+00	850.00
IUUC-Opr-070977	Ochotona princeps	74.12	0.00e+00	941.00
IUUC-Ont-072373	Oreochromis niloticus	73.91	0.00e+00	893.00
IUUC-Oan-073376	Ornithorhynchus anatinus	92.56	1.00e-148	519.00
IUUC-Ocu-074878	Oryctolagus cuniculus	74.09	0.00e+00	919.00
IUUC-Ola-086472	Oryzias latipes	75.65	0.00e+00	879.00
IUUC-Oga-088377	Otolemur garnettii	74.33	0.00e+00	926.00
IUUC-Oar-089540	Ovis aries	74.00	0.00e+00	921.00
IUUC-Ptr-090613	Pan troglodytes	74.33	0.00e+00	929.00
IUUC-Pan-092879	Papio anubis	74.36	0.00e+00	910.00
IUUC-Psi-093201	Pelodiscus sinensis	75.12	0.00e+00	881.00
IUUC-Pma-094620	Petromyzon marinus	67.86	0.00e+00	769.00
IUUC-Pfo-096615	Poecilia formosa	76.98	0.00e+00	882.00
IUUC-Pca-100625	Procavia capensis	73.91	0.00e+00	901.00
IUUC-Rno-105998	Rattus norvegicus	74.48	0.00e+00	912.00
IUUC-Sha-107523	Sarcophilus harrisii	73.28	0.00e+00	864.00
IUUC-Sar-113089	Sorex araneus	71.88	0.00e+00	701.00
IUUC-Ssc-115471	Sus scrofa	74.12	0.00e+00	906.00
IUUC-Tgu-117080	Taeniopygia guttata	74.09	0.00e+00	895.00
IUUC-Tru-117547	Takifugu rubripes	81.18	0.00e+00	849.00
IUUC-Tsy-119143	Tarsius syrichta	73.42	0.00e+00	910.00
IUUC-Tni-119693	Tetraodon nigroviridis	76.69	0.00e+00	860.00
IUUC-Ttr-129175	Tursiops truncatus	73.98	0.00e+00	909.00
IUUC-Vpa-130594	Vicugna pacos	67.92	0.00e+00	843.00
IUUC-Xtr-132579	Xenopus tropicalis	77.54	0.00e+00	939.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence