iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049965

Ensembl Protein ID

ENSLACP00000014384.1

UniProt Accession

H3AXL3; H3AXL3_LATCH

Genbank Protein ID

ENSLACP00000014384

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AFYH01019678

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000012661.1	ENSLACT00000014484.1	ENSLACP00000014384.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-08	35.1	202	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C+ l+    +p+ + w+CpkCr
   Q: 202  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVALT---YKPKGK-WYCPKCR 248
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MLAHYPNIER SQLVSYVEDY LECIETLPLE IQRNVSLLRE IDTKYQEVLK EADEVYEKYK 60
KEMDPSQRKR LQQHLQRILI SSQELGDEKI QIVTQVLELV ENRARQMETY SQFFQDPVEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTAGATTCA GCTGAGAAGG GGAATTTACA CACTGTATTT TTTTTCCCCA GATTGAATCC 60
TTCCTTGTTT GTGTTCGCTT GATGAATTGT AACAAACATG CTGGCGCATT ACCCGAACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

KEGG

lcm:102361488

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	80.15	1.00e-92	332.00
IUUC-Apl-003705	Anas platyrhynchos	84.30	4.00e-88	317.00
IUUC-Aca-004990	Anolis carolinensis	77.04	3.00e-94	338.00
IUUC-Ame-011426	Astyanax mexicanus	69.64	2.00e-85	308.00
IUUC-Bta-012721	Bos taurus	80.53	4.00e-93	333.00
IUUC-Cja-018960	Callithrix jacchus	80.53	5.00e-85	307.00
IUUC-Cfa-020869	Canis familiaris	79.77	2.00e-92	331.00
IUUC-Cpo-021414	Cavia porcellus	79.39	6.00e-91	327.00
IUUC-Csa-023304	Chlorocebus sabaeus	80.92	9.00e-86	309.00
IUUC-Dre-028562	Danio rerio	69.06	1.00e-95	342.00
IUUC-Dno-029945	Dasypus novemcinctus	80.53	1.00e-92	332.00
IUUC-Dor-030141	Dipodomys ordii	79.77	6.00e-90	323.00
IUUC-Ete-032709	Echinops telfairi	80.15	9.00e-101	359.00
IUUC-Eca-033432	Equus caballus	80.92	3.00e-93	334.00
IUUC-Eeu-035285	Erinaceus europaeus	85.29	5.00e-79	286.00
IUUC-Fca-036467	Felis catus	80.53	8.00e-93	333.00
IUUC-Fal-036700	Ficedula albicollis	83.56	9.00e-88	315.00
IUUC-Gga-040175	Gallus gallus	84.75	6.00e-89	319.00
IUUC-Hsa-045837	Homo sapiens	80.92	9.00e-86	309.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	80.53	4.00e-93	333.00
IUUC-Laf-053353	Loxodonta africana	81.78	4.00e-85	306.00
IUUC-Mcc-055155	Macaca mulatta	84.48	6.00e-63	232.00
IUUC-Meu-056470	Macropus eugenii	83.07	6.00e-101	360.00
IUUC-Mga-059570	Meleagris gallopavo	84.75	3.00e-88	317.00
IUUC-Mmr-061385	Microcebus murinus	80.53	3.00e-85	307.00
IUUC-Mdo-062144	Monodelphis domestica	83.07	5.00e-101	360.00
IUUC-Mmu-063215	Mus musculus	79.39	2.00e-92	332.00
IUUC-Mpu-065749	Mustela putorius furo	81.59	3.00e-84	304.00
IUUC-Mlu-067245	Myotis lucifugus	71.57	5.00e-71	259.00
IUUC-Nle-069968	Nomascus leucogenys	85.79	2.00e-72	265.00
IUUC-Ont-071524	Oreochromis niloticus	67.97	4.00e-89	320.00
IUUC-Ocu-074870	Oryctolagus cuniculus	81.30	2.00e-94	338.00
IUUC-Oga-088336	Otolemur garnettii	80.92	1.00e-85	309.00
IUUC-Oar-090136	Ovis aries	80.92	6.00e-94	336.00
IUUC-Ptr-091348	Pan troglodytes	85.26	1.00e-71	262.00
IUUC-Pan-092819	Papio anubis	80.92	9.00e-86	309.00
IUUC-Pfo-096633	Poecilia formosa	67.02	4.00e-80	290.00
IUUC-Pab-098346	Pongo abelii	81.30	2.00e-86	311.00
IUUC-Pca-100278	Procavia capensis	80.31	2.00e-98	351.00
IUUC-Pva-103190	Pteropus vampyrus	80.92	1.00e-93	335.00
IUUC-Rno-104940	Rattus norvegicus	78.63	4.00e-91	327.00
IUUC-Sha-107533	Sarcophilus harrisii	82.68	3.00e-100	357.00
IUUC-Sar-113630	Sorex araneus	83.82	3.00e-77	280.00
IUUC-Ssc-115734	Sus scrofa	80.92	2.00e-93	335.00
IUUC-Tgu-117034	Taeniopygia guttata	83.56	1.00e-87	315.00
IUUC-Tru-118168	Takifugu rubripes	60.64	2.00e-84	305.00
IUUC-Tsy-119494	Tarsius syrichta	84.74	5.00e-71	260.00
IUUC-Tni-120100	Tetraodon nigroviridis	61.98	7.00e-79	286.00
IUUC-Ttr-128442	Tursiops truncatus	83.82	2.00e-77	281.00
IUUC-Vpa-130063	Vicugna pacos	80.92	2.00e-93	335.00
IUUC-Xtr-132348	Xenopus tropicalis	71.65	1.00e-65	243.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence