iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059925

Ensembl Protein ID

ENSMGAP00000007761.2

UniProt Accession

G1N6N0; G1N6N0_MELGA

Protein Name

Uncharacterized protein

Gene Name

BCL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007602.2	ENSMGAT00000008543.2	ENSMGAP00000007761.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.10e-14	54.3	32	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.dvqpevfrallkFlYtgklden 68
           +Dv+++v++e+f+ahk vL+a+S  Fy+ f+ +l+ +   + ++++ ++ pe f  ll+F+Yt++l++ 
   Q: 32   TDVVIIVNREQFRAHKTVLMACSGLFYSIFTDQLKCN--LNVINLDpEINPEGFCILLDFMYTSRLNLR 98
           7**********************************76..69*****88*****************9875 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIIVNR EQFRAHKTVL MACSGLFYSI 60
FTDQLKCNLN VINLDPEINP EGFCILLDFM YTSRLNLREN NIMAVMATAL YLQMEHVVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTTTGAA AGAAACTTTT GGACTGTGAA TTGAGGCATT GGGTATGTAC ATTTCAATTT 60
TCCCCCTACC CACCTTCCCT ATACAACGTT GGATTAAATG TTTCTTTAGA CCCAGCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005657--C:replication fork
GO:0031490--F:chromatin DNA binding
GO:0001161--F:intronic transcription regulatory region sequence-specific DNA binding
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227--F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0030036--P:actin cytoskeleton organization
GO:0030183--P:B cell differentiation
GO:0000902--P:cell morphogenesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048821--P:erythrocyte development
GO:0002467--P:germinal center formation
GO:0043066--P:negative regulation of apoptotic process
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:2000773--P:negative regulation of cellular senescence
GO:0048294--P:negative regulation of isotype switching to IgE isotypes
GO:0032764--P:negative regulation of mast cell cytokine production
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0030890--P:positive regulation of B cell proliferation
GO:0051272--P:positive regulation of cellular component movement
GO:0031065--P:positive regulation of histone deacetylation
GO:0045666--P:positive regulation of neuron differentiation
GO:0000060--P:protein import into nucleus, translocation
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0043380--P:regulation of memory T cell differentiation
GO:0007266--P:Rho protein signal transduction
GO:0007283--P:spermatogenesis
GO:0042092--P:type 2 immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001625	Ailuropoda melanoleuca	77.98	0.00e+00	1125.00
IUUC-Apl-003263	Anas platyrhynchos	96.33	0.00e+00	1384.00
IUUC-Ame-010714	Astyanax mexicanus	59.05	0.00e+00	811.00
IUUC-Bta-012576	Bos taurus	77.78	0.00e+00	1116.00
IUUC-Cja-018906	Callithrix jacchus	78.90	0.00e+00	1150.00
IUUC-Cfa-021058	Canis familiaris	77.79	0.00e+00	1108.00
IUUC-Cpo-022328	Cavia porcellus	78.76	0.00e+00	1155.00
IUUC-Csa-023942	Chlorocebus sabaeus	77.70	0.00e+00	1128.00
IUUC-Cho-024599	Choloepus hoffmanni	78.84	0.00e+00	683.00
IUUC-Cin-025470	Ciona intestinalis	81.82	8.00e-60	224.00
IUUC-Csv-025860	Ciona savignyi	82.93	8.00e-60	224.00
IUUC-Dre-027605	Danio rerio	59.75	0.00e+00	823.00
IUUC-Dno-029476	Dasypus novemcinctus	73.30	0.00e+00	1073.00
IUUC-Dor-030724	Dipodomys ordii	77.64	0.00e+00	1122.00
IUUC-Ete-032678	Echinops telfairi	76.79	0.00e+00	1091.00
IUUC-Eca-034377	Equus caballus	78.34	0.00e+00	1138.00
IUUC-Eeu-034532	Erinaceus europaeus	72.27	0.00e+00	667.00
IUUC-Fca-036465	Felis catus	77.78	0.00e+00	1133.00
IUUC-Fal-036977	Ficedula albicollis	94.24	0.00e+00	1391.00
IUUC-Gmo-039515	Gadus morhua	59.15	1.00e-112	399.00
IUUC-Gga-040505	Gallus gallus	98.87	0.00e+00	1415.00
IUUC-Gac-041393	Gasterosteus aculeatus	58.33	0.00e+00	800.00
IUUC-Ggo-044500	Gorilla gorilla	77.98	0.00e+00	1135.00
IUUC-Hsa-046648	Homo sapiens	78.48	0.00e+00	1141.00
IUUC-Itr-048732	Ictidomys tridecemlineatus	75.00	0.00e+00	1077.00
IUUC-Lch-050387	Latimeria chalumnae	58.16	0.00e+00	761.00
IUUC-Loc-052103	Lepisosteus oculatus	62.57	0.00e+00	869.00
IUUC-Laf-053636	Loxodonta africana	77.28	0.00e+00	1135.00
IUUC-Mcc-055290	Macaca mulatta	78.06	0.00e+00	1133.00
IUUC-Meu-055910	Macropus eugenii	75.95	0.00e+00	1106.00
IUUC-Mvi-060431	Microbotryum violaceum	31.33	7.00e-04	38.10
IUUC-Mmr-060855	Microcebus murinus	79.04	0.00e+00	1139.00
IUUC-Mdo-062982	Monodelphis domestica	73.44	3.00e-80	291.00
IUUC-Mmu-063292	Mus musculus	78.37	0.00e+00	1116.00
IUUC-Mpu-066598	Mustela putorius furo	77.64	0.00e+00	1106.00
IUUC-Mlu-067370	Myotis lucifugus	78.40	0.00e+00	1114.00
IUUC-Nle-069870	Nomascus leucogenys	77.92	0.00e+00	1134.00
IUUC-Opr-070986	Ochotona princeps	77.15	0.00e+00	1103.00
IUUC-Ont-072475	Oreochromis niloticus	59.92	0.00e+00	769.00
IUUC-Oan-073596	Ornithorhynchus anatinus	80.76	0.00e+00	1159.00
IUUC-Ocu-073970	Oryctolagus cuniculus	78.40	0.00e+00	1154.00
IUUC-Ola-087102	Oryzias latipes	59.03	0.00e+00	798.00
IUUC-Oga-088873	Otolemur garnettii	78.37	0.00e+00	1145.00
IUUC-Oar-090083	Ovis aries	73.00	0.00e+00	1020.00
IUUC-Ptr-090628	Pan troglodytes	78.34	0.00e+00	1140.00
IUUC-Pan-092324	Papio anubis	77.56	0.00e+00	1123.00
IUUC-Psi-093695	Pelodiscus sinensis	86.46	0.00e+00	1229.00
IUUC-Pfo-096460	Poecilia formosa	58.52	0.00e+00	801.00
IUUC-Pab-098012	Pongo abelii	78.20	0.00e+00	1138.00
IUUC-Pca-100127	Procavia capensis	77.11	0.00e+00	1055.00
IUUC-Pva-102830	Pteropus vampyrus	77.92	0.00e+00	1117.00
IUUC-Rno-105752	Rattus norvegicus	78.93	0.00e+00	1123.00
IUUC-Sha-107259	Sarcophilus harrisii	78.96	0.00e+00	1154.00
IUUC-Sar-113610	Sorex araneus	75.65	0.00e+00	879.00
IUUC-Ssc-115327	Sus scrofa	78.34	0.00e+00	1134.00
IUUC-Tgu-116457	Taeniopygia guttata	95.49	0.00e+00	1407.00
IUUC-Tru-118520	Takifugu rubripes	58.19	0.00e+00	781.00
IUUC-Tsy-119245	Tarsius syrichta	43.21	3.00e-48	185.00
IUUC-Tni-119969	Tetraodon nigroviridis	58.91	0.00e+00	784.00
IUUC-Tbe-127327	Tupaia belangeri	71.45	0.00e+00	1013.00
IUUC-Ttr-129204	Tursiops truncatus	77.72	0.00e+00	1113.00
IUUC-Vpa-130647	Vicugna pacos	86.24	3.00e-56	212.00
IUUC-Xtr-132937	Xenopus tropicalis	67.89	0.00e+00	927.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence