iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115918

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU468625

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000029803.1	ENSSSCT00000025160.1	ENSSSCP00000024841.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.50e-13	50.9	436	500

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++    v ++lpn+  w+CpkC+++
   Q: 436  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegVVNDLPNC--WECPKCNHA 500
           79*********9977765156789********************99999999****..*******85 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

RYCLMSVKGC FTDFHIDFGG TSVWYHVFRG GKKFWLIPPT LHNLALYEEW VLSGKQSDIF 60
LGDRVERCQR IELKQGYTFF IPSGWIHAVY TPVDSLVFGG NILHSFNVPM QLRIYEIEDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTACTGTC TGATGAGCGT GAAAGGTTGT TTCACTGACT TCCACATCGA CTTTGGAGGC 60
ACTTCCGTTT GGTACCATGT TTTCCGGGGC GGGAAGGTGA GTTGAGTTTC CCCAGATCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	96.79	0.00e+00	1768.00
IUUC-Apl-003787	Anas platyrhynchos	81.91	0.00e+00	1519.00
IUUC-Aca-004247	Anolis carolinensis	76.24	0.00e+00	1355.00
IUUC-Ame-011114	Astyanax mexicanus	70.00	3.00e-130	458.00
IUUC-Bta-013531	Bos taurus	97.82	0.00e+00	1822.00
IUUC-Cja-018876	Callithrix jacchus	92.34	0.00e+00	1692.00
IUUC-Cfa-020857	Canis familiaris	97.34	0.00e+00	1811.00
IUUC-Cpo-021967	Cavia porcellus	92.12	0.00e+00	1618.00
IUUC-Csa-023210	Chlorocebus sabaeus	96.29	0.00e+00	1754.00
IUUC-Dre-028272	Danio rerio	60.41	0.00e+00	1101.00
IUUC-Dno-030034	Dasypus novemcinctus	93.47	0.00e+00	1688.00
IUUC-Dor-030736	Dipodomys ordii	86.42	0.00e+00	984.00
IUUC-Eca-034255	Equus caballus	98.10	0.00e+00	1826.00
IUUC-Eeu-035038	Erinaceus europaeus	98.56	0.00e+00	1057.00
IUUC-Fca-035786	Felis catus	97.25	0.00e+00	1868.00
IUUC-Fal-037589	Ficedula albicollis	81.67	0.00e+00	1551.00
IUUC-Gga-041103	Gallus gallus	84.38	0.00e+00	781.00
IUUC-Gac-041304	Gasterosteus aculeatus	54.97	0.00e+00	722.00
IUUC-Ggo-044522	Gorilla gorilla	95.66	0.00e+00	1564.00
IUUC-Hsa-045877	Homo sapiens	95.63	0.00e+00	1741.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	97.47	0.00e+00	1311.00
IUUC-Lch-049950	Latimeria chalumnae	76.52	0.00e+00	1443.00
IUUC-Loc-051972	Lepisosteus oculatus	76.74	0.00e+00	761.00
IUUC-Laf-053623	Loxodonta africana	96.01	0.00e+00	1681.00
IUUC-Mcc-054943	Macaca mulatta	96.20	0.00e+00	1748.00
IUUC-Meu-056259	Macropus eugenii	84.51	0.00e+00	1581.00
IUUC-Mga-059671	Meleagris gallopavo	83.13	0.00e+00	1579.00
IUUC-Mmr-061003	Microcebus murinus	95.91	0.00e+00	1782.00
IUUC-Mdo-062017	Monodelphis domestica	77.94	7.00e-153	533.00
IUUC-Mmu-063584	Mus musculus	94.40	0.00e+00	1721.00
IUUC-Mpu-066056	Mustela putorius furo	96.77	0.00e+00	1766.00
IUUC-Mlu-067850	Myotis lucifugus	96.40	0.00e+00	1813.00
IUUC-Nle-069837	Nomascus leucogenys	92.30	0.00e+00	1719.00
IUUC-Opr-070943	Ochotona princeps	91.35	0.00e+00	1624.00
IUUC-Ont-071663	Oreochromis niloticus	63.76	0.00e+00	1171.00
IUUC-Oan-072934	Ornithorhynchus anatinus	73.47	0.00e+00	1120.00
IUUC-Ocu-074706	Oryctolagus cuniculus	96.77	0.00e+00	1796.00
IUUC-Ola-086543	Oryzias latipes	60.07	0.00e+00	1149.00
IUUC-Oga-088671	Otolemur garnettii	81.96	0.00e+00	806.00
IUUC-Oar-089560	Ovis aries	91.62	0.00e+00	1726.00
IUUC-Ptr-090875	Pan troglodytes	95.63	0.00e+00	1768.00
IUUC-Pan-091788	Papio anubis	92.80	0.00e+00	1703.00
IUUC-Psi-093382	Pelodiscus sinensis	82.34	0.00e+00	1563.00
IUUC-Pfo-096272	Poecilia formosa	60.35	0.00e+00	1086.00
IUUC-Pab-097907	Pongo abelii	90.11	0.00e+00	1591.00
IUUC-Pca-100628	Procavia capensis	89.94	0.00e+00	1588.00
IUUC-Pva-102956	Pteropus vampyrus	96.33	0.00e+00	1180.00
IUUC-Rno-105722	Rattus norvegicus	95.00	0.00e+00	1675.00
IUUC-Sha-106626	Sarcophilus harrisii	79.68	0.00e+00	1504.00
IUUC-Tgu-117229	Taeniopygia guttata	69.57	0.00e+00	761.00
IUUC-Tru-118638	Takifugu rubripes	67.97	0.00e+00	694.00
IUUC-Tsy-118820	Tarsius syrichta	96.68	0.00e+00	696.00
IUUC-Tbe-127654	Tupaia belangeri	78.33	0.00e+00	1319.00
IUUC-Ttr-128821	Tursiops truncatus	94.31	0.00e+00	1652.00
IUUC-Xtr-131823	Xenopus tropicalis	73.93	0.00e+00	1316.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence