iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-119856

Ensembl Protein ID

ENSTNIP00000019135.1

UniProt Accession

H3DF41; H3DF41_TETNG

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000016046.1	ENSTNIT00000019363.1	ENSTNIP00000019135.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-10	41.3	13	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            + + y++++++  +L +kkGd +++i   ++d +W k+ k+++g++G +P+n+v+k
   Q: 13   ECVARYNFKGTSAHDLPFKKGDLLTII-VGTKDPNWYKA-KNAAGCEGTIPANYVQK 67
           68899**********************.99*********.7**************87 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MTNVQAPWPQ GTECVARYNF KGTSAHDLPF KKGDLLTIIV GTKDPNWYKA KNAAGCEGTI 60
PANYVQKREG VRSGGKLSLM PWFHGKITRD QAERLLYPPE TGLFLVREST NFPGDYTLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCAATG TCCAGGTCTG TGAAACAGCT GCAGGGTGCA AACGTTCGTG CAAAAGCCGC 60
AGACGCACGT CCGGTGAGTA GGCCCTGGGA ATTTTTACTC CTGATCTGTG ATGCGTCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004391	Anolis carolinensis	82.17	0.00e+00	779.00
IUUC-Cin-025513	Ciona intestinalis	54.48	2.00e-144	505.00
IUUC-Csv-025899	Ciona savignyi	50.32	7.00e-133	466.00
IUUC-Fal-037215	Ficedula albicollis	82.70	0.00e+00	786.00
IUUC-Gmo-039103	Gadus morhua	84.21	0.00e+00	782.00
IUUC-Gga-040506	Gallus gallus	82.25	0.00e+00	783.00
IUUC-Loc-052586	Lepisosteus oculatus	85.78	0.00e+00	808.00
IUUC-Meu-056387	Macropus eugenii	82.39	0.00e+00	780.00
IUUC-Mtr-058657	Medicago truncatula	29.29	1.00e-18	88.60
IUUC-Mga-060040	Meleagris gallopavo	80.95	0.00e+00	761.00
IUUC-Mdo-061871	Monodelphis domestica	82.62	0.00e+00	783.00
IUUC-Ont-072457	Oreochromis niloticus	91.93	0.00e+00	870.00
IUUC-Ola-087105	Oryzias latipes	90.56	0.00e+00	853.00
IUUC-Oga-087928	Otolemur garnettii	82.39	0.00e+00	780.00
IUUC-Pfo-096126	Poecilia formosa	91.28	0.00e+00	861.00
IUUC-Sha-106987	Sarcophilus harrisii	82.39	0.00e+00	782.00
IUUC-Sbi-114754	Sorghum bicolor	31.80	4.00e-20	92.00
IUUC-Tru-118712	Takifugu rubripes	93.50	0.00e+00	884.00
IUUC-Xtr-132763	Xenopus tropicalis	77.75	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence