iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggr-040107

Ensembl Protein ID

GGTG_00286T0

UniProt Accession

J3NG94; J3NG94_GAGT3

Genbank Protein ID

EJT80284.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

ADBI01000031

Gene Name

GGTG_00286

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GGTG_00286	GGTG_00286T0	GGTG_00286T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.10e-124	412.9	480	812

Active Site

Position(s)	Description	Evidence
781	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyk 98
           + dlkkrl+++f gE+gld+gG++ref++lls+e++np ++lf+ys+ d++tlq+np+sg+ npehl++F+f+Gr++g+a++++r+ld+++  ++yk
   Q: 480  ATDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGI-NPEHLNYFKFIGRVVGLAIFHRRFLDAFFIGALYK 575
           579*********************************************************9.89********************************* PP
   S: 99   lllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafre 195
           ++lgk + l d+e vd+++++sl+++ +n   di+   l+ tfs+++e +g +++e+L+p+G++i+VtneNk+eYv+l+v++r++++i+eq+eaf+ 
   Q: 576  MVLGKAVALPDMEGVDADFHRSLQWMIDN---DISGGILEQTFSTEDERFGVITVEDLIPNGRDIDVTNENKKEYVDLMVKWRIEKRIAEQFEAFKV 669
           ***************************99...9**************************************************************** PP
   S: 196  GfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfv 288
           Gf+e+ip++l+++F+e+elelli G +eidv+d+kk+t y+g yte++++iq+Fw+++++++ e+++++LqF+Tg+sr+P++Gf++l+    pr+f+
   Q: 670  GFHELIPIDLINVFDERELELLIGGIAEIDVDDWKKHTDYRG-YTESDEVIQFFWQTVRSWDGEQKSRLLQFTTGTSRIPVNGFKDLQgsdgPRRFT 765
           ****************************************76.****************************************************** PP
   S: 289  irkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           i+k+++ ++lP+++TCfn+L+LP+Y+s e+l++k+++A+eet gF++
   Q: 766  IEKAGEINNLPKAHTCFNRLDLPPYKSLEVLQQKMTIAVEETMGFGQ 812
           ***9999**************************************96 PP

Organism

Gaeumannomyces graminis

Protein Sequence
(Fasta)

MSGSRPNAGL PAQPNLRVTI IAADGLYKRD VFRFPDPFAV ATINSEQTKT TSVSKRTLNP 60
YWNESFDFRV TEDSILAVQV FDQKKFKKKD QGFLGVINIR IGDIIELAAD ADDQMLTRDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATCTCGCTC ACTCCCCTGT TGGTCAGGAA GAGCGAATTT TGGTACAGGC CCGCCTCGGT 60
CTCACAATCC TCGGCTGGTC CGGACTGCCT TTTTTTGTTC TTGTTTCAAT TTGGCGAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	46.66	4.00e-151	527.00
IUUC-Apl-003752	Anas platyrhynchos	47.95	4.00e-156	543.00
IUUC-Aca-005338	Anolis carolinensis	45.65	2.00e-149	521.00
IUUC-Ago-007742	Ashbya gossypii	71.26	0.00e+00	900.00
IUUC-Acl-008273	Aspergillus clavatus	73.21	0.00e+00	1113.00
IUUC-Afl-008713	Aspergillus flavus	72.54	0.00e+00	1121.00
IUUC-Afu-009103	Aspergillus fumigatus	70.62	0.00e+00	1096.00
IUUC-Ani-009259	Aspergillus nidulans	71.88	0.00e+00	1132.00
IUUC-Ang-009738	Aspergillus niger	72.11	0.00e+00	1142.00
IUUC-Aor-010053	Aspergillus oryzae	78.00	2.00e-142	496.00
IUUC-Ate-010529	Aspergillus terreus	71.72	0.00e+00	1131.00
IUUC-Ame-010810	Astyanax mexicanus	51.23	2.00e-138	485.00
IUUC-Bgr-012148	Blumeria graminis	76.14	0.00e+00	1169.00
IUUC-Bta-012679	Bos taurus	46.66	3.00e-151	527.00
IUUC-Bci-013785	Botrytis cinerea	78.00	0.00e+00	1251.00
IUUC-Cel-018299	Caenorhabditis elegans	43.44	5.00e-143	499.00
IUUC-Cja-018732	Callithrix jacchus	46.74	2.00e-150	525.00
IUUC-Cfa-021226	Canis familiaris	46.66	3.00e-151	527.00
IUUC-Cpo-021671	Cavia porcellus	46.66	3.00e-151	527.00
IUUC-Csa-023252	Chlorocebus sabaeus	47.51	1.00e-154	538.00
IUUC-Cho-024695	Choloepus hoffmanni	48.12	5.00e-156	543.00
IUUC-Cin-025212	Ciona intestinalis	46.34	1.00e-146	512.00
IUUC-Csv-026256	Ciona savignyi	45.49	3.00e-146	510.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	85.18	0.00e+00	1335.00
IUUC-Cne-026849	Cryptococcus neoformans	69.61	0.00e+00	862.00
IUUC-Dre-027770	Danio rerio	51.44	2.00e-139	488.00
IUUC-Dno-029466	Dasypus novemcinctus	46.66	3.00e-151	527.00
IUUC-Dor-030138	Dipodomys ordii	46.24	3.00e-146	511.00
IUUC-Dse-031241	Dothistroma septosporum	72.72	0.00e+00	1163.00
IUUC-Dme-032041	Drosophila melanogaster	44.35	2.00e-138	484.00
IUUC-Ete-032779	Echinops telfairi	44.67	2.00e-137	482.00
IUUC-Eca-033445	Equus caballus	46.66	7.00e-151	526.00
IUUC-Eeu-035247	Erinaceus europaeus	45.99	7.00e-149	520.00
IUUC-Fca-035605	Felis catus	47.86	1.00e-154	538.00
IUUC-Fal-037126	Ficedula albicollis	47.60	5.00e-154	536.00
IUUC-Fox-037774	Fusarium oxysporum	85.13	0.00e+00	1316.00
IUUC-Fso-038393	Fusarium solani	83.82	0.00e+00	1300.00
IUUC-Gmo-039674	Gadus morhua	43.03	2.00e-144	504.00
IUUC-Gga-040832	Gallus gallus	47.60	2.00e-154	538.00
IUUC-Gac-042020	Gasterosteus aculeatus	47.16	5.00e-146	510.00
IUUC-Ggo-045332	Gorilla gorilla	46.66	6.00e-151	526.00
IUUC-Hsa-045968	Homo sapiens	46.66	4.00e-151	527.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	47.68	3.00e-154	537.00
IUUC-Kpa-049273	Komagataella pastoris	66.38	0.00e+00	1031.00
IUUC-Lch-050445	Latimeria chalumnae	46.26	2.00e-148	518.00
IUUC-Loc-052645	Lepisosteus oculatus	46.85	2.00e-150	525.00
IUUC-Lma-052980	Leptosphaeria maculans	73.36	0.00e+00	686.00
IUUC-Laf-053850	Loxodonta africana	46.66	6.00e-151	526.00
IUUC-Mcc-055821	Macaca mulatta	46.66	5.00e-151	526.00
IUUC-Meu-055953	Macropus eugenii	40.27	2.00e-116	412.00
IUUC-Mor-057097	Magnaporthe oryzae	92.17	0.00e+00	1483.00
IUUC-Mpo-057442	Magnaporthe poae	89.50	0.00e+00	1331.00
IUUC-Mla-058996	Melampsora laricipopulina	67.04	0.00e+00	865.00
IUUC-Mga-059661	Meleagris gallopavo	47.60	2.00e-154	537.00
IUUC-Mvi-060395	Microbotryum violaceum	77.64	0.00e+00	805.00
IUUC-Mmr-061135	Microcebus murinus	47.86	1.00e-154	538.00
IUUC-Mdo-062505	Monodelphis domestica	46.26	1.00e-150	525.00
IUUC-Mmu-064136	Mus musculus	46.66	2.00e-151	528.00
IUUC-Mpu-066765	Mustela putorius furo	46.66	6.00e-151	526.00
IUUC-Mlu-067565	Myotis lucifugus	46.66	6.00e-151	526.00
IUUC-Nfi-068427	Neosartorya fischeri	72.89	0.00e+00	1128.00
IUUC-Ncr-068918	Neurospora crassa	82.13	0.00e+00	1261.00
IUUC-Nle-069244	Nomascus leucogenys	47.86	8.00e-155	539.00
IUUC-Opr-071044	Ochotona princeps	46.15	1.00e-148	519.00
IUUC-Ont-072226	Oreochromis niloticus	47.07	2.00e-153	535.00
IUUC-Oan-073497	Ornithorhynchus anatinus	46.22	9.00e-150	522.00
IUUC-Ocu-074160	Oryctolagus cuniculus	46.08	1.00e-148	519.00
IUUC-Ola-087467	Oryzias latipes	45.74	4.00e-146	510.00
IUUC-Oga-088460	Otolemur garnettii	46.66	7.00e-151	526.00
IUUC-Oar-090198	Ovis aries	46.66	8.00e-150	523.00
IUUC-Ptr-090939	Pan troglodytes	46.66	4.00e-151	527.00
IUUC-Pan-092284	Papio anubis	46.66	4.00e-151	527.00
IUUC-Psi-093645	Pelodiscus sinensis	46.31	3.00e-151	527.00
IUUC-Pma-094364	Petromyzon marinus	50.30	4.00e-139	486.00
IUUC-Pno-095118	Phaeosphaeria nodorum	72.88	0.00e+00	1156.00
IUUC-Pfo-096171	Poecilia formosa	46.73	3.00e-152	530.00
IUUC-Pab-098088	Pongo abelii	46.66	4.00e-151	527.00
IUUC-Pca-100596	Procavia capensis	43.80	7.00e-141	493.00
IUUC-Pva-102354	Pteropus vampyrus	46.66	9.00e-151	526.00
IUUC-Pgr-103620	Puccinia graminis	66.45	0.00e+00	839.00
IUUC-Ptt-103806	Puccinia triticina	76.33	0.00e+00	677.00
IUUC-Pte-104016	Pyrenophora teres	74.45	0.00e+00	1152.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	74.45	0.00e+00	1152.00
IUUC-Rno-105318	Rattus norvegicus	46.66	2.00e-151	528.00
IUUC-Sce-106289	Saccharomyces cerevisiae	72.80	0.00e+00	894.00
IUUC-Sha-107482	Sarcophilus harrisii	46.42	3.00e-147	514.00
IUUC-Sja-107941	Schizosaccharomyces japonicus	63.95	0.00e+00	1012.00
IUUC-Spo-108171	Schizosaccharomyces pombe	65.66	0.00e+00	1024.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	78.20	0.00e+00	1244.00
IUUC-Sar-113761	Sorex araneus	47.68	2.00e-153	534.00
IUUC-Sbi-114042	Sorghum bicolor	45.50	3.00e-93	337.00
IUUC-Sre-114929	Sporisorium reilianum	70.95	0.00e+00	870.00
IUUC-Ssc-115368	Sus scrofa	46.23	2.00e-148	518.00
IUUC-Tgu-117130	Taeniopygia guttata	46.69	4.00e-149	520.00
IUUC-Tru-118610	Takifugu rubripes	44.89	1.00e-153	535.00
IUUC-Tsy-119492	Tarsius syrichta	46.66	5.00e-150	523.00
IUUC-Tni-119993	Tetraodon nigroviridis	46.31	3.00e-144	504.00
IUUC-Tre-122203	Trichoderma reesei	82.51	0.00e+00	1283.00
IUUC-Tvi-122595	Trichoderma virens	81.91	0.00e+00	1303.00
IUUC-Tme-126897	Tuber melanosporum	70.27	0.00e+00	1069.00
IUUC-Tbe-127793	Tupaia belangeri	46.91	2.00e-128	451.00
IUUC-Ttr-128275	Tursiops truncatus	45.85	6.00e-147	513.00
IUUC-Uma-129332	Ustilago maydis	70.78	0.00e+00	846.00
IUUC-Vda-129753	Verticillium dahliae	82.57	0.00e+00	1283.00
IUUC-Vpa-130503	Vicugna pacos	45.33	1.00e-137	482.00
IUUC-Xtr-132859	Xenopus tropicalis	47.84	9.00e-152	529.00
IUUC-Xma-133797	Xiphophorus maculatus	47.50	7.00e-150	523.00
IUUC-Yli-134668	Yarrowia lipolytica	72.28	0.00e+00	926.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence