iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052662

Ensembl Protein ID

ENSLOCP00000014577.1

UniProt Accession

W5N1R8; W5N1R8_LEPOC

Genbank Protein ID

ENSLOCP00000014577

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01017234

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000011831.1	ENSLOCT00000014606.1	ENSLOCP00000014577.1
ENSLOCG00000011831.1	ENSLOCT00000014614.1	ENSLOCP00000014585.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.30e-135	449.6	664	993

Active Site

Position(s)	Description	Evidence
963	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
            lk+rl++ef+ E+gld+gGv+re+++llske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+++g+lld ++
   Q: 664  ILKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVFHGKLLDGFF 752
           6899************************************************************************************* PP
   S: 93   sksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyr 181
            ++fyk++lgk+++l+d+e+vd+e+y+slk+i+en   d +e  ldl+f+++ee++g+t++++Lkp+G+++ Vtn+Nk+eY++lv+++r
   Q: 753  IRPFYKMMLGKQITLKDMESVDSEYYNSLKWILEN---DPTE--LDLRFCIDEENFGQTYQVDLKPSGSEMVVTNDNKKEYIDLVIQWR 836
           *********************************99...6666..7******************************************** PP
   S: 182  lkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTg 270
           + +++++q++af eGf+e+i ++l+++F+e+elell+cG  ++dv+d++++t yk+gy +++p+iqwFw+++  +++e+r ++LqFvTg
   Q: 837  FVNRVQKQMNAFLEGFTELIAIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTG 925
           ***************************************************************************************** PP
   S: 271  ssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +sr+P++Gfael     p+lf+i++++++d+lP+++TCfn+L+LP+Y+s e+l+e+Ll+A+e+++gFe
   Q: 926  TSRVPMNGFAELYgsngPQLFTIEQWGTPDKLPRAHTCFNRLDLPTYESFEELRERLLLAVENAEGFE 993
           *******************************************************************8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MATNIEPIYG LSEDDDESRI LRVRVIAGID LAKKDIFGAS DPYVKLSLYV ADENRELALV 60
QTKTIKKTLN PKWNEEFYFR VSPHNHRLLF EVFDENRLVD KNTHAHKNGL FHLGQTRDDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGATACATT GTTATCATGT TCACCGCCTT CGCCTGCTTT TTATTGGCTA GCTCTGTGCG 60
CTTGGTATTT ATGGAAACCT TGTGGTTGGT TTAATTAGTT TTCAGTCAGA AAAGAGAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

PRINTS

PR00360--C2DOMAIN

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	79.75	0.00e+00	1431.00
IUUC-Apl-003893	Anas platyrhynchos	80.97	0.00e+00	1486.00
IUUC-Aca-004744	Anolis carolinensis	77.82	0.00e+00	1431.00
IUUC-Ago-007742	Ashbya gossypii	48.58	7.00e-160	557.00
IUUC-Acl-008273	Aspergillus clavatus	49.09	8.00e-160	557.00
IUUC-Afl-008713	Aspergillus flavus	49.09	1.00e-159	556.00
IUUC-Afu-009103	Aspergillus fumigatus	49.42	7.00e-161	561.00
IUUC-Ani-009259	Aspergillus nidulans	49.25	1.00e-159	556.00
IUUC-Ang-009738	Aspergillus niger	48.84	6.00e-159	554.00
IUUC-Aor-010053	Aspergillus oryzae	56.71	3.00e-99	354.00
IUUC-Ate-010529	Aspergillus terreus	49.59	4.00e-161	561.00
IUUC-Ame-010810	Astyanax mexicanus	88.82	0.00e+00	1075.00
IUUC-Bgr-012148	Blumeria graminis	46.45	1.00e-151	530.00
IUUC-Bta-012679	Bos taurus	81.38	0.00e+00	1346.00
IUUC-Cja-018732	Callithrix jacchus	81.04	0.00e+00	1528.00
IUUC-Cfa-021226	Canis familiaris	81.20	0.00e+00	1511.00
IUUC-Cpo-021671	Cavia porcellus	79.78	0.00e+00	1480.00
IUUC-Csa-023344	Chlorocebus sabaeus	79.49	0.00e+00	1509.00
IUUC-Cho-024832	Choloepus hoffmanni	95.17	0.00e+00	719.00
IUUC-Dre-027770	Danio rerio	84.17	0.00e+00	1538.00
IUUC-Dno-029466	Dasypus novemcinctus	80.92	0.00e+00	1527.00
IUUC-Dor-030138	Dipodomys ordii	78.33	0.00e+00	1379.00
IUUC-Ete-033145	Echinops telfairi	75.80	0.00e+00	1078.00
IUUC-Eca-033445	Equus caballus	81.81	0.00e+00	1341.00
IUUC-Eeu-035247	Erinaceus europaeus	79.68	0.00e+00	1200.00
IUUC-Fca-035489	Felis catus	79.98	0.00e+00	1292.00
IUUC-Fal-037604	Ficedula albicollis	79.15	0.00e+00	1513.00
IUUC-Gmo-039674	Gadus morhua	80.48	0.00e+00	1475.00
IUUC-Gga-040703	Gallus gallus	81.52	0.00e+00	1539.00
IUUC-Gac-042020	Gasterosteus aculeatus	82.62	0.00e+00	1510.00
IUUC-Ggo-045332	Gorilla gorilla	79.85	0.00e+00	1443.00
IUUC-Hsa-045968	Homo sapiens	80.82	0.00e+00	1519.00
IUUC-Lch-050443	Latimeria chalumnae	83.05	0.00e+00	1371.00
IUUC-Laf-053850	Loxodonta africana	80.39	0.00e+00	1494.00
IUUC-Mcc-055821	Macaca mulatta	81.20	0.00e+00	1499.00
IUUC-Meu-056712	Macropus eugenii	63.09	2.00e-173	603.00
IUUC-Mla-058996	Melampsora laricipopulina	53.59	9.00e-148	517.00
IUUC-Mvi-060395	Microbotryum violaceum	54.38	1.00e-150	527.00
IUUC-Mmr-060798	Microcebus murinus	77.28	0.00e+00	1400.00
IUUC-Mdo-062173	Monodelphis domestica	79.02	0.00e+00	1524.00
IUUC-Mmu-064136	Mus musculus	80.54	0.00e+00	1506.00
IUUC-Mpu-066765	Mustela putorius furo	80.85	0.00e+00	1496.00
IUUC-Mlu-067565	Myotis lucifugus	81.24	0.00e+00	1342.00
IUUC-Nfi-068427	Neosartorya fischeri	49.42	7.00e-161	561.00
IUUC-Nle-069070	Nomascus leucogenys	77.82	0.00e+00	1454.00
IUUC-Opr-071044	Ochotona princeps	89.07	0.00e+00	1078.00
IUUC-Ont-072044	Oreochromis niloticus	82.82	0.00e+00	1591.00
IUUC-Oan-073032	Ornithorhynchus anatinus	77.56	0.00e+00	1228.00
IUUC-Ocu-074160	Oryctolagus cuniculus	79.80	0.00e+00	1468.00
IUUC-Ola-087467	Oryzias latipes	80.79	0.00e+00	1499.00
IUUC-Oga-088460	Otolemur garnettii	80.02	0.00e+00	1317.00
IUUC-Oar-090198	Ovis aries	80.79	0.00e+00	1493.00
IUUC-Ptr-090939	Pan troglodytes	80.82	0.00e+00	1519.00
IUUC-Pan-092284	Papio anubis	80.92	0.00e+00	1518.00
IUUC-Psi-093645	Pelodiscus sinensis	80.62	0.00e+00	1531.00
IUUC-Pma-094364	Petromyzon marinus	82.47	0.00e+00	841.00
IUUC-Pfo-096768	Poecilia formosa	92.65	0.00e+00	979.00
IUUC-Pab-098088	Pongo abelii	81.11	0.00e+00	1504.00
IUUC-Pca-100714	Procavia capensis	71.54	0.00e+00	978.00
IUUC-Pva-102354	Pteropus vampyrus	79.69	0.00e+00	1431.00
IUUC-Ptt-103806	Puccinia triticina	53.70	2.00e-122	433.00
IUUC-Rno-105318	Rattus norvegicus	80.10	0.00e+00	1469.00
IUUC-Sce-106289	Saccharomyces cerevisiae	49.17	1.00e-161	563.00
IUUC-Sha-107482	Sarcophilus harrisii	80.88	0.00e+00	1360.00
IUUC-Ssc-115950	Sus scrofa	64.07	0.00e+00	1056.00
IUUC-Tgu-117130	Taeniopygia guttata	81.22	0.00e+00	1514.00
IUUC-Tru-118610	Takifugu rubripes	83.73	0.00e+00	1555.00
IUUC-Tsy-119492	Tarsius syrichta	76.16	0.00e+00	1360.00
IUUC-Tni-120113	Tetraodon nigroviridis	77.94	0.00e+00	1392.00
IUUC-Ttr-128235	Tursiops truncatus	88.21	0.00e+00	994.00
IUUC-Xtr-132859	Xenopus tropicalis	81.12	0.00e+00	1524.00
IUUC-Xma-133797	Xiphophorus maculatus	82.62	0.00e+00	1519.00
IUUC-Yli-134668	Yarrowia lipolytica	46.63	2.00e-157	550.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence