iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	74.01	0.00e+00	881.00	IUUC-Hsa-046144
UBD/Alpha-Helix/UBA	74.01	0.00e+00	881.00	IUUC-Hsa-046144

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAKQWGISLV VKLTKSHEQN YLPGERLLPS PPCRLTMNMV QGSAFLAKLM KSADTFELKY 60
DFSCELYRLS TYSTFPAGVP VSERSLARAG FYYTGVNDKV KCFSCGLMLD NWKQGDSPIE 120

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Nucleotide Sequence
(Fasta)

CGGGGCTGGA GCAGTGGCCA GGGCCAAGCT TGGGACGACT CAGAGGCGTC GCGACACTCA 60
GCCACACCCC ACAGGCCGGG CGAGGGTGCC ACCTCGGAGA TCAGAGGTCA GTGCTGGCGT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0045121--C:membrane raft
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0043027--F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:1990001--P:inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:0060546--P:negative regulation of necroptotic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:0051291--P:protein heterooligomerization
GO:0034121--P:regulation of toll-like receptor signaling pathway
GO:0007283--P:spermatogenesis

KEGG

rno:78971

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002499	Amborella trichopoda	44.64	4.00e-12	65.50
IUUC-Ate-010501	Aspergillus terreus	33.54	7.00e-18	86.30
IUUC-Bgr-012051	Blumeria graminis	32.48	9.00e-14	72.40
IUUC-Bta-013105	Bos taurus	69.21	0.00e+00	804.00
IUUC-Cfa-020667	Canis familiaris	69.37	0.00e+00	808.00
IUUC-Cho-024929	Choloepus hoffmanni	71.52	0.00e+00	825.00
IUUC-Csv-026182	Ciona savignyi	29.79	2.00e-66	247.00
IUUC-Cgl-026472	Colletotrichum gloeosporioides	34.52	2.00e-18	88.60
IUUC-Cne-027029	Cryptococcus neoformans	33.33	5.00e-17	82.80
IUUC-Ete-032768	Echinops telfairi	64.90	0.00e+00	695.00
IUUC-Eca-034417	Equus caballus	74.83	0.00e+00	875.00
IUUC-Gmo-038477	Gadus morhua	53.64	4.00e-172	598.00
IUUC-Ggo-044605	Gorilla gorilla	74.55	0.00e+00	857.00
IUUC-Hsa-046144	Homo sapiens	74.01	0.00e+00	871.00
IUUC-Itr-048379	Ictidomys tridecemlineatus	75.66	0.00e+00	914.00
IUUC-Kpa-049324	Komagataella pastoris	28.42	5.00e-12	67.40
IUUC-Laf-053720	Loxodonta africana	74.17	0.00e+00	841.00
IUUC-Mor-057252	Magnaporthe oryzae	35.62	1.00e-17	85.50
IUUC-Mvi-060388	Microbotryum violaceum	23.40	7.00e-08	52.40
IUUC-Mmr-060719	Microcebus murinus	76.99	0.00e+00	900.00
IUUC-Mmu-063340	Mus musculus	90.03	0.00e+00	1051.00
IUUC-Mpu-066740	Mustela putorius furo	67.88	0.00e+00	796.00
IUUC-Mlu-067988	Myotis lucifugus	73.84	0.00e+00	837.00
IUUC-Nle-069942	Nomascus leucogenys	74.67	0.00e+00	857.00
IUUC-Opr-070597	Ochotona princeps	74.67	0.00e+00	869.00
IUUC-Ocu-074698	Oryctolagus cuniculus	75.66	0.00e+00	895.00
IUUC-Oba-075516	Oryza barthii	35.06	3.00e-07	50.80
IUUC-Olo-080871	Oryza longistaminata	37.31	3.00e-07	50.80
IUUC-Ome-081390	Oryza meridionalis	35.06	3.00e-07	50.80
IUUC-Oni-082480	Oryza nivara	35.06	3.00e-07	50.80
IUUC-Osa-085816	Oryza sativa	40.43	2.00e-08	53.10
IUUC-Oga-089080	Otolemur garnettii	72.07	0.00e+00	868.00
IUUC-Oar-089496	Ovis aries	74.16	0.00e+00	853.00
IUUC-Ptr-091203	Pan troglodytes	74.50	0.00e+00	862.00
IUUC-Pma-094277	Petromyzon marinus	38.81	2.00e-119	422.00
IUUC-Ppa-095167	Physcomitrella patens	41.07	3.00e-11	62.80
IUUC-Pop-098944	Populus trichocarpa	40.62	9.00e-11	60.80
IUUC-Pte-104098	Pyrenophora teres	33.33	4.00e-16	79.00
IUUC-Smo-109461	Selaginella moellendorffii	41.07	3.00e-11	62.00
IUUC-Sar-113239	Sorex araneus	70.39	0.00e+00	774.00
IUUC-Tsy-118958	Tarsius syrichta	75.63	1.00e-164	572.00
IUUC-Ttr-128766	Tursiops truncatus	75.50	0.00e+00	897.00
IUUC-Vpa-130761	Vicugna pacos	76.16	0.00e+00	891.00
IUUC-Xtr-132031	Xenopus tropicalis	55.93	0.00e+00	635.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence