iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040708

Ensembl Protein ID

ENSGALP00000053534.1

UniProt Accession

A0A1D5PL20; A0A1D5PL20_CHICK

Genbank Protein ID

ENSGALP00000053534

Protein Name

Hypermethylated in cancer 1 protein

Genbank Nucleotide ID

AADN04000066

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000042077.1	ENSGALT00000079270.1	ENSGALP00000053534.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.50e-12	48.1	52	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkld 66
           +Dvi+vv++  f+ahk +LaasS ++++l  ++       +  +++ + v+p+ fr +l+F+Ytg+l 
   Q: 52   CDVIIVVQNALFRAHKNILAASSAYLKSLVVHD-------NLLNLDhEmVSPGIFRLILDFIYTGRLG 112
           9*****************************773.......4556663479****************96 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MRVHRELGWL AEGSGRAGRR ARGAMLEAME VPSHSRQLLL QLNTQRTKGF LCDVIIVVQN 60
ALFRAHKNIL AASSAYLKSL VVHDNLLNLD HEMVSPGIFR LILDFIYTGR LGECEPGGEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAGCGGCG CTGCTCGGAG TTCAGGCCGG GGTCAGGGGG AGTTCGCAGC CCGGGTTTCA 60
CCTCCGAGCT GGCGGCGTCG GGAGCCCCGA GGAACCGCCG CCGCCGACCG CTCCGAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	63.13	2.00e-107	383.00
IUUC-Aca-004680	Anolis carolinensis	80.61	3.00e-70	259.00
IUUC-Ame-010967	Astyanax mexicanus	64.94	1.00e-107	383.00
IUUC-Bta-013567	Bos taurus	61.43	8.00e-106	377.00
IUUC-Cja-019621	Callithrix jacchus	86.52	3.00e-39	153.00
IUUC-Cfa-020731	Canis familiaris	63.30	8.00e-111	394.00
IUUC-Cpo-021326	Cavia porcellus	62.50	1.00e-115	410.00
IUUC-Csa-023645	Chlorocebus sabaeus	61.67	9.00e-109	387.00
IUUC-Dre-028027	Danio rerio	49.66	1.00e-163	570.00
IUUC-Dno-028900	Dasypus novemcinctus	60.49	9.00e-111	394.00
IUUC-Fal-036980	Ficedula albicollis	91.32	0.00e+00	1032.00
IUUC-Gac-041742	Gasterosteus aculeatus	81.11	2.00e-87	316.00
IUUC-Ggo-044591	Gorilla gorilla	68.25	2.00e-105	376.00
IUUC-Hsa-046769	Homo sapiens	61.18	1.00e-106	380.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	61.10	3.00e-109	389.00
IUUC-Lch-049412	Latimeria chalumnae	69.85	0.00e+00	917.00
IUUC-Loc-051883	Lepisosteus oculatus	66.99	2.00e-114	406.00
IUUC-Laf-053358	Loxodonta africana	61.92	1.00e-108	386.00
IUUC-Mcc-054981	Macaca mulatta	61.67	8.00e-109	387.00
IUUC-Meu-056181	Macropus eugenii	68.09	2.00e-66	246.00
IUUC-Mga-059592	Meleagris gallopavo	97.89	3.00e-159	554.00
IUUC-Mmr-061560	Microcebus murinus	68.25	5.00e-109	388.00
IUUC-Mdo-062511	Monodelphis domestica	55.49	4.00e-155	541.00
IUUC-Mmu-064258	Mus musculus	60.93	4.00e-108	385.00
IUUC-Mpu-065911	Mustela putorius furo	63.30	1.00e-110	393.00
IUUC-Mlu-067575	Myotis lucifugus	65.92	2.00e-95	342.00
IUUC-Ont-072493	Oreochromis niloticus	53.83	2.00e-105	376.00
IUUC-Ola-086584	Oryzias latipes	66.67	9.00e-104	370.00
IUUC-Oga-088774	Otolemur garnettii	58.71	2.00e-176	612.00
IUUC-Ptr-090491	Pan troglodytes	68.89	3.00e-92	331.00
IUUC-Pfo-096282	Poecilia formosa	55.56	7.00e-102	364.00
IUUC-Pab-098488	Pongo abelii	61.18	1.00e-106	380.00
IUUC-Pva-102421	Pteropus vampyrus	60.48	1.00e-112	400.00
IUUC-Rno-105528	Rattus norvegicus	60.93	5.00e-104	371.00
IUUC-Sar-113478	Sorex araneus	74.89	6.00e-91	328.00
IUUC-Ssc-115420	Sus scrofa	59.86	1.00e-111	397.00
IUUC-Tgu-116642	Taeniopygia guttata	96.10	0.00e+00	1115.00
IUUC-Tru-118583	Takifugu rubripes	63.92	3.00e-98	352.00
IUUC-Xtr-132210	Xenopus tropicalis	73.15	0.00e+00	920.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence