iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033807

Ensembl Protein ID

ENSECAP00000012056.1

UniProt Accession

F7CNV6; F7CNV6_HORSE

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013955.1	ENSECAT00000015037.1	ENSECAP00000012056.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.70e-26	90.5	350	376

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpR 28
           ++ WaC++CTf+Ne++av C+mC+rpR
   Q: 350  RGRWACQSCTFENEAAAVLCAMCERPR 376
           578***********************9 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MPAEEERAFL AAREELASAL RRDSGQAFSS EQLRPLLVTS LPPATRYLQL DAARLVRCNA 60
HGEPRNYLNT LSTALNILEK YGRNLLSPQR PRYWRGVKFN NPVFRSTVDA VQGGRDVLRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGGCGG AGGAGGAGCG GGCCTTCCTG GCGGCCCGCG AGGAGCTGGC GAGCGCCCTG 60
AGGAGGGATT CCGGGCAGGC GTTTTCCTCG GAGCAGCTCC GGCCGCTGCT GGTCACCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR018997--PUB_domain
IPR026254--RNF31
IPR032065--RNF31-UBA
IPR015940--UBA
IPR001876--Znf_RanBP2
IPR017907--Znf_RING_CS

PROSITE

PS50030--UBA
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1

Pfam

PF16678--HOIP-UBA
PF01485--IBR
PF09409--PUB

SMART

SM00647--IBR
SM00547--ZnF_RBZ

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0023035--P:CD40 signaling pathway
GO:0060546--P:negative regulation of necroptotic process
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002017	Ailuropoda melanoleuca	92.90	0.00e+00	1807.00
IUUC-Aca-004719	Anolis carolinensis	56.98	0.00e+00	902.00
IUUC-Ame-011924	Astyanax mexicanus	37.33	1.00e-120	427.00
IUUC-Bta-012795	Bos taurus	88.62	0.00e+00	1704.00
IUUC-Cja-019168	Callithrix jacchus	90.32	0.00e+00	1798.00
IUUC-Cfa-020767	Canis familiaris	93.31	0.00e+00	1842.00
IUUC-Cpo-022291	Cavia porcellus	86.46	0.00e+00	1783.00
IUUC-Csa-024246	Chlorocebus sabaeus	90.83	0.00e+00	1550.00
IUUC-Cho-024866	Choloepus hoffmanni	59.65	0.00e+00	862.00
IUUC-Cin-025568	Ciona intestinalis	35.01	5.00e-97	348.00
IUUC-Dre-027426	Danio rerio	44.61	0.00e+00	768.00
IUUC-Dno-029925	Dasypus novemcinctus	87.87	0.00e+00	1720.00
IUUC-Dor-030389	Dipodomys ordii	81.98	0.00e+00	1587.00
IUUC-Dme-031816	Drosophila melanogaster	40.49	4.00e-89	324.00
IUUC-Ete-032383	Echinops telfairi	95.03	0.00e+00	731.00
IUUC-Eeu-034745	Erinaceus europaeus	78.46	0.00e+00	856.00
IUUC-Fca-036464	Felis catus	93.08	0.00e+00	1845.00
IUUC-Gmo-039121	Gadus morhua	42.76	7.00e-180	624.00
IUUC-Gac-041766	Gasterosteus aculeatus	46.37	0.00e+00	838.00
IUUC-Ggo-045259	Gorilla gorilla	91.88	0.00e+00	1806.00
IUUC-Hsa-046269	Homo sapiens	91.79	0.00e+00	1802.00
IUUC-Itr-048764	Ictidomys tridecemlineatus	88.99	0.00e+00	1919.00
IUUC-Lch-049622	Latimeria chalumnae	52.57	0.00e+00	1106.00
IUUC-Laf-054027	Loxodonta africana	89.04	0.00e+00	1736.00
IUUC-Mcc-054906	Macaca mulatta	91.70	0.00e+00	1853.00
IUUC-Meu-056354	Macropus eugenii	70.04	0.00e+00	1368.00
IUUC-Mmr-060835	Microcebus murinus	90.38	0.00e+00	1754.00
IUUC-Mdo-061883	Monodelphis domestica	76.17	0.00e+00	1556.00
IUUC-Mmu-064014	Mus musculus	83.66	0.00e+00	1690.00
IUUC-Mlu-067075	Myotis lucifugus	90.01	0.00e+00	1760.00
IUUC-Nle-069954	Nomascus leucogenys	91.79	0.00e+00	1821.00
IUUC-Opr-070399	Ochotona princeps	82.84	0.00e+00	1697.00
IUUC-Ont-071593	Oreochromis niloticus	46.86	0.00e+00	863.00
IUUC-Oan-073591	Ornithorhynchus anatinus	91.21	6.00e-47	178.00
IUUC-Ocu-073785	Oryctolagus cuniculus	70.98	0.00e+00	1349.00
IUUC-Ola-087261	Oryzias latipes	46.25	0.00e+00	848.00
IUUC-Oga-088724	Otolemur garnettii	90.95	0.00e+00	1771.00
IUUC-Oar-089318	Ovis aries	89.19	0.00e+00	1828.00
IUUC-Ptr-091249	Pan troglodytes	91.88	0.00e+00	1835.00
IUUC-Pan-092080	Papio anubis	91.61	0.00e+00	1871.00
IUUC-Pma-094655	Petromyzon marinus	50.63	1.00e-67	249.00
IUUC-Pfo-096097	Poecilia formosa	45.08	0.00e+00	845.00
IUUC-Pab-098380	Pongo abelii	89.56	0.00e+00	1767.00
IUUC-Pca-101024	Procavia capensis	82.59	0.00e+00	1664.00
IUUC-Pva-102289	Pteropus vampyrus	92.26	0.00e+00	1802.00
IUUC-Rno-105864	Rattus norvegicus	84.08	0.00e+00	1674.00
IUUC-Sha-107428	Sarcophilus harrisii	76.96	0.00e+00	1492.00
IUUC-Sar-113745	Sorex araneus	87.41	0.00e+00	1762.00
IUUC-Ssc-116246	Sus scrofa	92.76	0.00e+00	1796.00
IUUC-Tru-118704	Takifugu rubripes	45.89	0.00e+00	828.00
IUUC-Tsy-119077	Tarsius syrichta	89.44	0.00e+00	1497.00
IUUC-Tni-120343	Tetraodon nigroviridis	45.92	0.00e+00	826.00
IUUC-Tbe-127822	Tupaia belangeri	92.55	0.00e+00	846.00
IUUC-Ttr-129179	Tursiops truncatus	87.62	0.00e+00	1740.00
IUUC-Xtr-132864	Xenopus tropicalis	50.67	0.00e+00	955.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence