iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025232

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01000411

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000018771.1	ENSCINT00000031441.1	ENSCINP00000031549.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-91	306.3	706	1027

Active Site

Position(s)	Description	Evidence
997	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++kk l+v+f gEeg+d gGv +ef+ l++ke+ +p++g+f++ ++++  ++ + +      e + ++ ++G ++g+a++++ ++d+
   Q: 706  SFKKPLMVKFDGEEGQDEGGVRKEFFMLILKEVLDPKYGMFRFYDESHLIWFSDWEL-----ESEMMYFLVGLICGLAIYNDTIIDI 787
           57999*****************************************99999966544.....45667779***************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaes..dieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
            ++ ++yk+llg++  + dl+e+dp+l +s++ ++e++++  +ie++ ++l+f+vs +++get+e++L+ gG+nipVt +N++eYv+
   Q: 788  CFPLVLYKKLLGEPPLFTDLAELDPTLSRSMNHLLEYQSDvhSIEDT-FCLNFTVSRDNFGETTEVDLIAGGSNIPVTADNRKEYVQ 873
           *************************************8434488886.*************************************** PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
            ++++ +++++++++eaf +Gf++v+  ++l+lF++ el  ++ G++++++e+++k + ykg+y +++p+i+ Fw+v+++fs ee+k
   Q: 874  SYINHLFNTSVQRKFEAFNKGFHKVCGGKILQLFRATELMEMVVGNQNYNWEEFEKSADYKGEYYRQHPVIRIFWRVFHKFSLEEKK 960
           *************************************************************************************** PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +fL F+Tgs+++P+ G++ +      i+  ++s+++lP ++TCfn+L+LP Y+++ ++  kL  A+ +++gF 
   Q: 961  DFLLFLTGSNKIPITGVKII------IQPvKTSENHLPVAHTCFNLLDLPYYTTEHTMDMKLKQAMLNNQGFY 1027
           **************998744......44436899*************************************96 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MYAWGKSIIG KSFGNGANLQ VPTEINCFGK TIIKSVRVSR TIAVFLLEDG TVHTFGAEND 60
NIGHSAGSTK VSALETVHIV DIALGDSHIL AIDDKGKVYG WGGNDKDQLG WTDGNCYPSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTATGCGT GGGGGAAAAG CATTATTGGG AAGTCATTTG GAAACGGGGC CAATCTGCAA 60
GTGCCCACAG AAATAAACTG CTTTGGAAAA ACAATAATAA AATCAGTTCG AGTCAGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001666	Ailuropoda melanoleuca	42.82	0.00e+00	771.00
IUUC-Apl-003295	Anas platyrhynchos	42.86	0.00e+00	810.00
IUUC-Aca-004336	Anolis carolinensis	43.64	0.00e+00	815.00
IUUC-Ame-010768	Astyanax mexicanus	43.41	0.00e+00	809.00
IUUC-Bta-013279	Bos taurus	42.54	0.00e+00	763.00
IUUC-Bci-013697	Botrytis cinerea	32.41	6.00e-61	228.00
IUUC-Cel-018150	Caenorhabditis elegans	31.27	4.00e-138	484.00
IUUC-Cja-019023	Callithrix jacchus	42.63	0.00e+00	765.00
IUUC-Cfa-021074	Canis familiaris	42.63	0.00e+00	766.00
IUUC-Cpo-021461	Cavia porcellus	41.97	0.00e+00	739.00
IUUC-Csa-024261	Chlorocebus sabaeus	42.62	0.00e+00	764.00
IUUC-Cho-024325	Choloepus hoffmanni	42.79	7.00e-135	473.00
IUUC-Dre-028829	Danio rerio	44.27	0.00e+00	796.00
IUUC-Dno-029241	Dasypus novemcinctus	40.79	0.00e+00	724.00
IUUC-Dor-030158	Dipodomys ordii	48.01	2.00e-121	428.00
IUUC-Dse-031239	Dothistroma septosporum	32.30	8.00e-66	244.00
IUUC-Dme-032103	Drosophila melanogaster	37.97	0.00e+00	660.00
IUUC-Ete-032642	Echinops telfairi	39.26	0.00e+00	682.00
IUUC-Eca-033317	Equus caballus	42.47	0.00e+00	763.00
IUUC-Eeu-035098	Erinaceus europaeus	51.52	6.00e-73	267.00
IUUC-Fca-035682	Felis catus	42.95	0.00e+00	769.00
IUUC-Fal-036969	Ficedula albicollis	43.07	0.00e+00	822.00
IUUC-Gmo-038671	Gadus morhua	42.35	0.00e+00	785.00
IUUC-Gga-041174	Gallus gallus	43.08	0.00e+00	815.00
IUUC-Gac-042600	Gasterosteus aculeatus	42.62	0.00e+00	778.00
IUUC-Ggo-044589	Gorilla gorilla	42.82	0.00e+00	776.00
IUUC-Hsa-046772	Homo sapiens	42.72	0.00e+00	774.00
IUUC-Itr-048311	Ictidomys tridecemlineatus	41.05	0.00e+00	725.00
IUUC-Lch-050301	Latimeria chalumnae	41.41	0.00e+00	761.00
IUUC-Loc-052684	Lepisosteus oculatus	42.24	0.00e+00	771.00
IUUC-Laf-053844	Loxodonta africana	42.71	0.00e+00	767.00
IUUC-Mcc-055531	Macaca mulatta	41.50	0.00e+00	751.00
IUUC-Mga-059563	Meleagris gallopavo	41.94	0.00e+00	755.00
IUUC-Mmr-060954	Microcebus murinus	42.58	0.00e+00	766.00
IUUC-Mdo-062246	Monodelphis domestica	44.62	0.00e+00	762.00
IUUC-Mmu-063369	Mus musculus	42.84	0.00e+00	795.00
IUUC-Mpu-065936	Mustela putorius furo	43.54	0.00e+00	748.00
IUUC-Mlu-067326	Myotis lucifugus	42.39	0.00e+00	741.00
IUUC-Nle-069453	Nomascus leucogenys	43.14	0.00e+00	770.00
IUUC-Opr-070891	Ochotona princeps	37.85	2.00e-161	561.00
IUUC-Ont-071720	Oreochromis niloticus	43.95	0.00e+00	789.00
IUUC-Oan-073464	Ornithorhynchus anatinus	44.27	0.00e+00	763.00
IUUC-Ocu-074207	Oryctolagus cuniculus	42.58	0.00e+00	728.00
IUUC-Ola-086762	Oryzias latipes	43.17	0.00e+00	746.00
IUUC-Oga-088435	Otolemur garnettii	42.82	0.00e+00	765.00
IUUC-Oar-089233	Ovis aries	42.54	0.00e+00	763.00
IUUC-Ptr-091368	Pan troglodytes	42.80	0.00e+00	776.00
IUUC-Pan-092300	Papio anubis	42.62	0.00e+00	764.00
IUUC-Psi-093406	Pelodiscus sinensis	42.56	0.00e+00	807.00
IUUC-Pma-094113	Petromyzon marinus	43.33	0.00e+00	627.00
IUUC-Pfo-097021	Poecilia formosa	43.38	0.00e+00	823.00
IUUC-Pab-098327	Pongo abelii	42.91	0.00e+00	778.00
IUUC-Pca-100855	Procavia capensis	35.74	2.00e-113	402.00
IUUC-Pva-102506	Pteropus vampyrus	39.02	2.00e-176	611.00
IUUC-Pte-104055	Pyrenophora teres	31.12	1.00e-47	184.00
IUUC-Rno-105457	Rattus norvegicus	42.67	0.00e+00	794.00
IUUC-Sha-106632	Sarcophilus harrisii	43.41	0.00e+00	789.00
IUUC-Spo-108271	Schizosaccharomyces pombe	31.93	6.00e-69	254.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	33.54	1.00e-64	240.00
IUUC-Sar-113679	Sorex araneus	36.61	1.00e-106	379.00
IUUC-Ssc-115473	Sus scrofa	40.72	0.00e+00	721.00
IUUC-Tgu-116849	Taeniopygia guttata	41.91	0.00e+00	758.00
IUUC-Tru-118206	Takifugu rubripes	42.11	0.00e+00	728.00
IUUC-Tsy-119619	Tarsius syrichta	36.35	1.00e-112	399.00
IUUC-Tni-120233	Tetraodon nigroviridis	42.75	0.00e+00	739.00
IUUC-Tbe-127640	Tupaia belangeri	39.36	0.00e+00	671.00
IUUC-Ttr-129172	Tursiops truncatus	40.66	0.00e+00	722.00
IUUC-Vpa-130448	Vicugna pacos	42.48	0.00e+00	766.00
IUUC-Xtr-132719	Xenopus tropicalis	38.92	0.00e+00	631.00
IUUC-Xma-133389	Xiphophorus maculatus	43.10	0.00e+00	818.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence