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Tag Content
iUUCD ID IUUC-Csa-023807
Ensembl Protein ID ENSCSAP00000011746.1
UniProt Accession A0A0D9RT07; A0A0D9RT07_CHLSB
Genbank Protein ID ENSCSAP00000011746
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AQIB01147668
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCSAG00000015664.1 ENSCSAT00000013756.1 ENSCSAP00000011746.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.00e-15 57.6 833 873
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 833  WCFVCSKGGS----LLCCESCPAAFHPDCLNIE----MPDGS-WFCNDCR 873
           8*********....*******************....9***8.******8 PP
   
Organism Chlorocebus sabaeus
Protein Sequence
(Fasta)
MEFSIKQSPL SVQSVVKCIK MKQAPEILGS ANGKTPSCEV NRECSVFLSK AQLSSSLQEG 60
VMQKFNGHDA LPFIPADKLK DLTSRVFNGE PGAHDAKLRF ESQETKGIGT PPNTTPIKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Csa-023807|E3,PHD|Chlorocebus sabaeus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGTTCTAAGA ACGGAAGCAT CTGGGCTGGA TGGAATTTAG CATCAAGCAG AGTCCCCTTT 60
CTGTTCAGAG TGTTGTAAAG TGCATAAAGA TGAAGCAGGC ACCAGAAATC CTCGGCAGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Csa-023807|E3,PHD|Chlorocebus sabaeus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
KEGG csab:103246476
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 92.49 0.00e+00 2439.00
IUUC-Apl-003677 Anas platyrhynchos 81.03 0.00e+00 2155.00
IUUC-Aca-004278 Anolis carolinensis 75.75 0.00e+00 1414.00
IUUC-Ame-011932 Astyanax mexicanus 70.79 0.00e+00 1028.00
IUUC-Bta-012522 Bos taurus 86.33 0.00e+00 2266.00
IUUC-Cja-018908 Callithrix jacchus 97.76 0.00e+00 2501.00
IUUC-Cfa-020894 Canis familiaris 91.62 0.00e+00 2475.00
IUUC-Cpo-021982 Cavia porcellus 89.99 0.00e+00 2393.00
IUUC-Cho-024405 Choloepus hoffmanni 74.37 0.00e+00 741.00
IUUC-Csv-026298 Ciona savignyi 39.29 7.00e-58 218.00
IUUC-Dre-027492 Danio rerio 71.47 0.00e+00 1065.00
IUUC-Dno-030020 Dasypus novemcinctus 88.09 0.00e+00 2090.00
IUUC-Dor-031103 Dipodomys ordii 84.76 0.00e+00 2160.00
IUUC-Ete-032488 Echinops telfairi 82.12 0.00e+00 2148.00
IUUC-Eca-034066 Equus caballus 93.65 0.00e+00 2508.00
IUUC-Eeu-035199 Erinaceus europaeus 71.35 0.00e+00 763.00
IUUC-Fca-035434 Felis catus 87.65 0.00e+00 2005.00
IUUC-Fal-037113 Ficedula albicollis 79.02 0.00e+00 2162.00
IUUC-Gmo-039686 Gadus morhua 70.47 0.00e+00 1016.00
IUUC-Gga-040273 Gallus gallus 79.18 0.00e+00 2133.00
IUUC-Gac-042123 Gasterosteus aculeatus 50.90 0.00e+00 1253.00
IUUC-Ggo-044643 Gorilla gorilla 98.36 0.00e+00 2561.00
IUUC-Hsa-046380 Homo sapiens 98.65 0.00e+00 2536.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 93.38 0.00e+00 1449.00
IUUC-Lch-050217 Latimeria chalumnae 67.09 0.00e+00 1752.00
IUUC-Lpe-051201 Leersia perrieri 28.48 1.00e-10 61.60
IUUC-Loc-052766 Lepisosteus oculatus 59.06 0.00e+00 1285.00
IUUC-Laf-053780 Loxodonta africana 90.22 0.00e+00 2445.00
IUUC-Mcc-054928 Macaca mulatta 99.63 0.00e+00 2595.00
IUUC-Meu-056184 Macropus eugenii 75.72 0.00e+00 794.00
IUUC-Mga-059576 Meleagris gallopavo 79.91 0.00e+00 2138.00
IUUC-Mmr-061045 Microcebus murinus 93.05 0.00e+00 2488.00
IUUC-Mdo-062576 Monodelphis domestica 83.42 0.00e+00 2229.00
IUUC-Mmu-063640 Mus musculus 90.81 0.00e+00 2375.00
IUUC-Mac-065303 Musa acuminata 29.22 3.00e-11 63.50
IUUC-Mpu-066512 Mustela putorius furo 92.71 0.00e+00 2439.00
IUUC-Mlu-067280 Myotis lucifugus 80.32 0.00e+00 1102.00
IUUC-Nle-069896 Nomascus leucogenys 98.51 0.00e+00 2437.00
IUUC-Ont-072197 Oreochromis niloticus 73.29 0.00e+00 1038.00
IUUC-Oan-072724 Ornithorhynchus anatinus 79.93 0.00e+00 1384.00
IUUC-Ocu-074758 Oryctolagus cuniculus 89.78 0.00e+00 2316.00
IUUC-Olo-080702 Oryza longistaminata 41.47 4.00e-45 176.00
IUUC-Opu-083371 Oryza punctata 41.88 1.00e-46 182.00
IUUC-Oga-088702 Otolemur garnettii 92.34 0.00e+00 2141.00
IUUC-Oar-089736 Ovis aries 81.28 0.00e+00 1997.00
IUUC-Ptr-091055 Pan troglodytes 98.65 0.00e+00 2533.00
IUUC-Pan-092752 Papio anubis 99.87 0.00e+00 1479.00
IUUC-Psi-093620 Pelodiscus sinensis 80.73 0.00e+00 2170.00
IUUC-Pfo-097464 Poecilia formosa 50.75 0.00e+00 1199.00
IUUC-Pab-098051 Pongo abelii 98.43 0.00e+00 2566.00
IUUC-Pop-099927 Populus trichocarpa 28.96 6.00e-12 66.20
IUUC-Pca-100273 Procavia capensis 89.84 0.00e+00 2381.00
IUUC-Pva-102473 Pteropus vampyrus 78.61 0.00e+00 1946.00
IUUC-Rno-105056 Rattus norvegicus 90.60 0.00e+00 2380.00
IUUC-Sha-107494 Sarcophilus harrisii 84.28 0.00e+00 2217.00
IUUC-Sar-113310 Sorex araneus 91.78 0.00e+00 1905.00
IUUC-Sbi-114581 Sorghum bicolor 35.19 6.00e-10 58.20
IUUC-Ssc-116344 Sus scrofa 86.06 0.00e+00 2273.00
IUUC-Tgu-116786 Taeniopygia guttata 80.63 0.00e+00 2159.00
IUUC-Tru-117638 Takifugu rubripes 50.75 0.00e+00 1237.00
IUUC-Tsy-118937 Tarsius syrichta 97.31 0.00e+00 1567.00
IUUC-Tni-120452 Tetraodon nigroviridis 53.66 0.00e+00 1173.00
IUUC-Tae-125237 Triticum aestivum 31.51 1.00e-07 50.10
IUUC-Tbe-127291 Tupaia belangeri 88.28 0.00e+00 1529.00
IUUC-Ttr-129017 Tursiops truncatus 83.99 0.00e+00 1790.00
IUUC-Xtr-132673 Xenopus tropicalis 67.62 0.00e+00 1790.00
Created Date 25-Jun-2017

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