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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046067
UUCD1 version UUC-HoS-00779
Ensembl Protein ID ENSP00000340979.4
UniProt Accession Q8N4F7; C9JL66; Q8NB61; RN175_HUMAN
Genbank Protein ID BAC03680.1; EAX04951.1; AAH34385.1
Protein Name RING finger protein 175
Genbank Nucleotide ID AK091509; AC020703; BC034385
Gene Name RNF175
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000145428.14 ENST00000347063.8 ENSP00000340979.4
ENSG00000145428.14 ENST00000513656.5 ENSP00000421761.1
ENSG00000145428.14 ENST00000503694.5 ENSP00000424430.1
ENSG00000145428.14 ENST00000508248.1 ENSP00000427472.1
ENSG00000145428.14 ENST00000507512.1 ENSP00000424563.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsiteCircNetmicroRNA
TRANSFACTargetScanRepTarmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexMentha
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTM
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 4.60e-07 31.9 227 277
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C + +          ++ ++ l+C+Hvfh+ C+  w    +   k+++CP+C+
   Q: 227  CAVCGQKIiveldeegliEN-TYQLSCNHVFHEFCIRGW----CIVGKKQTCPYCK 277
           9***9988888887777555.999***************....889999******7 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MAAGTAARKA APVLEAPPQQ EQLSHTKLSA EDTWNLQQER MYKMHRGHDS MHVEMILIFL 60
CVLVIAQIVL VQWRQRHGRS YNLVTLLQMW VVPLYFTIKL YWWRFLSMWG MFSVITSYIL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046067|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCAGTCCTGC CGCCCGGTAA CAAAACCGGG GTTCCCGCCA CACGCACCCG GTAGGGCTCA 60
AGACGCTTTA TCGGCGACAA TGGCTGGCTG AATGGGAGGC CTGAGGTTCT GAAGGAACCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046067|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
SMART

SM00184--RING
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ubiquitin-dependent ERAD pathway
KEGG hsa:285533
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001696 Ailuropoda melanoleuca 93.40 7.00e-179 619.00
IUUC-Ani-009461 Aspergillus nidulans 29.21 3.00e-04 40.40
IUUC-Bta-012417 Bos taurus 93.06 3.00e-179 620.00
IUUC-Cja-018928 Callithrix jacchus 95.30 2.00e-180 625.00
IUUC-Csa-024195 Chlorocebus sabaeus 97.66 2.00e-150 524.00
IUUC-Dre-028154 Danio rerio 76.53 3.00e-150 524.00
IUUC-Dno-030042 Dasypus novemcinctus 94.04 1.00e-172 598.00
IUUC-Ete-032805 Echinops telfairi 78.23 4.00e-136 477.00
IUUC-Eeu-035318 Erinaceus europaeus 83.02 7.00e-149 520.00
IUUC-Fca-036592 Felis catus 96.09 6.00e-179 619.00
IUUC-Gmo-039004 Gadus morhua 73.47 2.00e-131 461.00
IUUC-Gac-042092 Gasterosteus aculeatus 74.75 6.00e-145 506.00
IUUC-Ggo-044923 Gorilla gorilla 98.43 0.00e+00 645.00
IUUC-Itr-049039 Ictidomys tridecemlineatus 94.79 5.00e-177 613.00
IUUC-Loc-052668 Lepisosteus oculatus 76.03 4.00e-151 527.00
IUUC-Mcc-055430 Macaca mulatta 97.78 0.00e+00 646.00
IUUC-Mmr-060873 Microcebus murinus 91.36 6.00e-164 569.00
IUUC-Mpu-066792 Mustela putorius furo 94.97 0.00e+00 627.00
IUUC-Mlu-066938 Myotis lucifugus 89.41 5.00e-174 603.00
IUUC-Nle-069138 Nomascus leucogenys 98.74 0.00e+00 651.00
IUUC-Opr-070342 Ochotona princeps 90.88 1.00e-168 585.00
IUUC-Ont-072601 Oreochromis niloticus 76.82 9.00e-148 516.00
IUUC-Ocu-074696 Oryctolagus cuniculus 92.74 7.00e-180 622.00
IUUC-Ola-086347 Oryzias latipes 76.49 6.00e-147 513.00
IUUC-Oga-089139 Otolemur garnettii 95.11 2.00e-176 611.00
IUUC-Ptr-091158 Pan troglodytes 99.37 0.00e+00 654.00
IUUC-Pfo-096037 Poecilia formosa 76.53 8.00e-142 496.00
IUUC-Pab-097624 Pongo abelii 97.80 0.00e+00 642.00
IUUC-Sar-113082 Sorex araneus 90.15 1.00e-134 472.00
IUUC-Tsy-118809 Tarsius syrichta 92.18 6.00e-161 559.00
IUUC-Tbe-127912 Tupaia belangeri 73.86 6.00e-129 453.00
IUUC-Vpa-130356 Vicugna pacos 91.88 3.00e-165 574.00
Created Date 25-Jun-2017

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