iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088613

Ensembl Protein ID

ENSOGAP00000000562.2

UniProt Accession

H0WGU6; H0WGU6_OTOGA

Genbank Protein ID

ENSOGAP00000000562

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03044520

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000000624.2	ENSOGAT00000000625.2	ENSOGAP00000000562.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.20e-23	82.8	455	510

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklnds 56
           +ee+let+ vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q++ l+k++++++ds
   Q: 455  QEEDLETMSVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENDAFEDS 510
           79****************************************************98 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MSHQPLSCLT EKGDSPNETT GNGPPSLAHP NLDTFTPEEL LRQMKELLTE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERQFFETQS REAKQRLMAL SHENEKLKEE LGKLKGKSER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCACC AACCTCTCAG CTGCCTGACT GAAAAAGGGG ACAGCCCCAA CGAAACCACT 60
GGAAATGGCC CCCCCAGTCT GGCTCACCCA AACCTGGACA CGTTCACCCC GGAGGAGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	81.47	0.00e+00	809.00
IUUC-Apl-003812	Anas platyrhynchos	55.76	8.00e-148	516.00
IUUC-Aca-004625	Anolis carolinensis	53.82	1.00e-146	513.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.20e-02	33.50
IUUC-Ame-011116	Astyanax mexicanus	48.10	7.00e-54	204.00
IUUC-Bta-013240	Bos taurus	82.79	0.00e+00	894.00
IUUC-Cja-019911	Callithrix jacchus	86.57	0.00e+00	867.00
IUUC-Cfa-020330	Canis familiaris	84.17	0.00e+00	847.00
IUUC-Cpo-021753	Cavia porcellus	81.82	0.00e+00	834.00
IUUC-Csa-023662	Chlorocebus sabaeus	88.47	0.00e+00	890.00
IUUC-Cho-024574	Choloepus hoffmanni	68.09	6.00e-127	447.00
IUUC-Cme-027299	Cyanidioschyzon merolae	33.70	5.00e-03	35.80
IUUC-Dre-027720	Danio rerio	40.63	2.00e-90	325.00
IUUC-Dno-029079	Dasypus novemcinctus	79.35	0.00e+00	771.00
IUUC-Dor-030890	Dipodomys ordii	81.58	0.00e+00	850.00
IUUC-Dme-032072	Drosophila melanogaster	29.30	4.00e-04	38.90
IUUC-Ete-032568	Echinops telfairi	79.32	0.00e+00	715.00
IUUC-Eca-033528	Equus caballus	83.95	0.00e+00	859.00
IUUC-Eeu-035219	Erinaceus europaeus	75.73	0.00e+00	804.00
IUUC-Fca-035852	Felis catus	82.97	0.00e+00	842.00
IUUC-Fal-036862	Ficedula albicollis	59.21	1.00e-146	513.00
IUUC-Gmo-038735	Gadus morhua	38.21	2.00e-72	266.00
IUUC-Gga-040939	Gallus gallus	56.38	5.00e-147	514.00
IUUC-Gac-041580	Gasterosteus aculeatus	43.03	2.00e-93	336.00
IUUC-Ggo-045034	Gorilla gorilla	78.31	0.00e+00	790.00
IUUC-Hsa-046624	Homo sapiens	87.26	0.00e+00	892.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	77.84	0.00e+00	817.00
IUUC-Lch-049720	Latimeria chalumnae	49.01	7.00e-79	287.00
IUUC-Loc-052185	Lepisosteus oculatus	44.35	5.00e-101	361.00
IUUC-Laf-054079	Loxodonta africana	82.69	0.00e+00	827.00
IUUC-Mcc-055674	Macaca mulatta	87.95	0.00e+00	872.00
IUUC-Meu-056769	Macropus eugenii	81.66	2.00e-69	256.00
IUUC-Mga-060203	Meleagris gallopavo	56.70	3.00e-139	488.00
IUUC-Mmr-061492	Microcebus murinus	87.61	0.00e+00	861.00
IUUC-Mdo-063051	Monodelphis domestica	74.87	0.00e+00	781.00
IUUC-Mmu-063409	Mus musculus	76.52	0.00e+00	845.00
IUUC-Mpu-065907	Mustela putorius furo	77.48	0.00e+00	821.00
IUUC-Mlu-066957	Myotis lucifugus	83.30	0.00e+00	795.00
IUUC-Ncr-068766	Neurospora crassa	33.33	1.70e-01	30.80
IUUC-Nle-069973	Nomascus leucogenys	87.95	0.00e+00	897.00
IUUC-Opr-071049	Ochotona princeps	79.17	0.00e+00	739.00
IUUC-Ont-071915	Oreochromis niloticus	42.86	2.00e-90	326.00
IUUC-Oan-072965	Ornithorhynchus anatinus	71.58	0.00e+00	748.00
IUUC-Ocu-074029	Oryctolagus cuniculus	76.30	0.00e+00	679.00
IUUC-Ola-087019	Oryzias latipes	40.25	2.00e-83	303.00
IUUC-Oar-090386	Ovis aries	82.44	0.00e+00	889.00
IUUC-Ptr-091619	Pan troglodytes	87.09	0.00e+00	888.00
IUUC-Pan-092178	Papio anubis	87.48	0.00e+00	869.00
IUUC-Psi-093214	Pelodiscus sinensis	61.51	1.00e-156	546.00
IUUC-Pfo-096901	Poecilia formosa	41.02	1.00e-82	300.00
IUUC-Pab-097560	Pongo abelii	78.77	0.00e+00	751.00
IUUC-Pca-100853	Procavia capensis	72.97	7.00e-122	431.00
IUUC-Pva-102255	Pteropus vampyrus	83.30	0.00e+00	799.00
IUUC-Rno-105812	Rattus norvegicus	78.25	0.00e+00	828.00
IUUC-Sha-107225	Sarcophilus harrisii	78.55	7.00e-151	526.00
IUUC-Sar-113736	Sorex araneus	72.51	4.00e-124	438.00
IUUC-Ssc-115422	Sus scrofa	85.20	0.00e+00	902.00
IUUC-Tgu-116924	Taeniopygia guttata	55.44	2.00e-139	489.00
IUUC-Tru-117695	Takifugu rubripes	39.73	6.00e-84	305.00
IUUC-Tsy-119090	Tarsius syrichta	83.57	9.00e-154	536.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.20	2.00e-86	313.00
IUUC-Tbe-127970	Tupaia belangeri	72.54	1.00e-137	483.00
IUUC-Ttr-129244	Tursiops truncatus	84.34	0.00e+00	840.00
IUUC-Vpa-130313	Vicugna pacos	82.27	0.00e+00	794.00
IUUC-Xtr-132115	Xenopus tropicalis	44.77	2.00e-98	352.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence