iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050123

Ensembl Protein ID

ENSLACP00000006698.1

UniProt Accession

H3AAM7; H3AAM7_LATCH

Genbank Protein ID

ENSLACP00000006698

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01232152

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000005940.1	ENSLACT00000006752.1	ENSLACP00000006698.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.60e-22	77.7	32	98
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.50e-11	42.2	130	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+++++e ++h++vLaa+S++F+a fl++leesk k +v+++dv+pev++ +++++Yt+++++n+
   Q: 32   DCVLKIKEKELPCHRLVLAACSPYFRAIFLSDLEESK-KREVNLEDVDPEVMSSIVNYIYTSEIEIND 98
           9************************************.*************************99885 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+Ncl+i+r++ ++dcp+L+ aa+dfi++ F
   Q: 130  LSNCLAIFRLGLMLDCPRLAVAARDFICNRF 160
           69****************************9 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MPTEQSEELR LYQQTLLQDG LKDLLDSNRF VDCVLKIKEK ELPCHRLVLA ACSPYFRAIF 60
LSDLEESKKR EVNLEDVDPE VMSSIVNYIY TSEIEINDQN VQDIFAAASM FQIPSIFTVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAAATCAG TCCCTCATCG TCTTTATTTT AGAGTGTGTA TATGTATGTG TATGTGTGTG 60
TGTGCATGTG CAGTAGCATT GTGACTAAAT ATAAAACCCA ATTGGAAAGG GGAGAGCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

KEGG

lcm:102350763

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	62.16	0.00e+00	798.00
IUUC-Apl-003748	Anas platyrhynchos	70.66	0.00e+00	899.00
IUUC-Aca-005275	Anolis carolinensis	63.99	0.00e+00	820.00
IUUC-Ame-011294	Astyanax mexicanus	63.74	0.00e+00	805.00
IUUC-Bta-012801	Bos taurus	64.73	0.00e+00	861.00
IUUC-Bdi-014457	Brachypodium distachyon	27.27	2.00e-12	67.40
IUUC-Cja-019795	Callithrix jacchus	65.00	0.00e+00	771.00
IUUC-Cpo-022436	Cavia porcellus	65.50	0.00e+00	865.00
IUUC-Csa-023105	Chlorocebus sabaeus	65.05	0.00e+00	844.00
IUUC-Cin-025237	Ciona intestinalis	31.68	2.00e-74	273.00
IUUC-Dre-028603	Danio rerio	64.37	0.00e+00	826.00
IUUC-Eca-034393	Equus caballus	65.14	0.00e+00	819.00
IUUC-Fca-035823	Felis catus	56.90	0.00e+00	728.00
IUUC-Fal-037632	Ficedula albicollis	70.29	0.00e+00	880.00
IUUC-Gmo-039697	Gadus morhua	60.52	0.00e+00	791.00
IUUC-Gga-040525	Gallus gallus	71.31	0.00e+00	905.00
IUUC-Gac-042421	Gasterosteus aculeatus	65.57	0.00e+00	840.00
IUUC-Gma-043151	Glycine max	29.44	1.00e-15	77.80
IUUC-Ggo-045596	Gorilla gorilla	65.05	0.00e+00	841.00
IUUC-Hsa-046235	Homo sapiens	65.21	0.00e+00	841.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	65.16	0.00e+00	873.00
IUUC-Loc-051824	Lepisosteus oculatus	70.13	0.00e+00	903.00
IUUC-Mcc-054909	Macaca mulatta	65.21	0.00e+00	844.00
IUUC-Meu-055972	Macropus eugenii	63.81	0.00e+00	839.00
IUUC-Mpo-057526	Magnaporthe poae	25.45	7.00e-08	50.40
IUUC-Mga-059451	Meleagris gallopavo	71.47	0.00e+00	918.00
IUUC-Mmr-060736	Microcebus murinus	65.58	0.00e+00	872.00
IUUC-Mdo-062563	Monodelphis domestica	66.31	0.00e+00	666.00
IUUC-Mmu-063549	Mus musculus	66.02	0.00e+00	870.00
IUUC-Mpu-066262	Mustela putorius furo	65.38	0.00e+00	868.00
IUUC-Mlu-067210	Myotis lucifugus	64.52	0.00e+00	857.00
IUUC-Opr-070384	Ochotona princeps	61.61	0.00e+00	771.00
IUUC-Ont-071273	Oreochromis niloticus	67.05	0.00e+00	841.00
IUUC-Ocu-074499	Oryctolagus cuniculus	64.58	0.00e+00	839.00
IUUC-Ola-087175	Oryzias latipes	64.48	0.00e+00	826.00
IUUC-Oga-088855	Otolemur garnettii	64.94	0.00e+00	867.00
IUUC-Ptr-091028	Pan troglodytes	62.90	1.00e-163	569.00
IUUC-Pan-091827	Papio anubis	65.05	0.00e+00	844.00
IUUC-Psi-092998	Pelodiscus sinensis	71.31	0.00e+00	905.00
IUUC-Pma-094586	Petromyzon marinus	60.50	2.00e-98	351.00
IUUC-Pfo-096216	Poecilia formosa	65.63	0.00e+00	838.00
IUUC-Pva-102331	Pteropus vampyrus	58.33	0.00e+00	756.00
IUUC-Rno-105613	Rattus norvegicus	65.47	0.00e+00	764.00
IUUC-Sha-107091	Sarcophilus harrisii	64.98	0.00e+00	877.00
IUUC-Ssl-108403	Sclerotinia sclerotiorum	26.98	5.00e-06	44.70
IUUC-Ssc-116276	Sus scrofa	65.06	0.00e+00	865.00
IUUC-Tgu-116494	Taeniopygia guttata	70.34	0.00e+00	910.00
IUUC-Tru-118614	Takifugu rubripes	67.55	0.00e+00	870.00
IUUC-Tni-119776	Tetraodon nigroviridis	65.95	0.00e+00	851.00
IUUC-Tbe-127806	Tupaia belangeri	59.23	0.00e+00	775.00
IUUC-Ttr-128813	Tursiops truncatus	64.35	0.00e+00	852.00
IUUC-Xtr-132942	Xenopus tropicalis	70.75	0.00e+00	901.00
IUUC-Xma-133573	Xiphophorus maculatus	65.69	0.00e+00	806.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence