iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D+++ vg++ef++h++vLaa+S++F+a fl e +     ++  +++v+p+v++++l++lYt+++ ++
   Q: 34   DCVVRVGEREFPCHRLVLAACSPYFRARFLAEPDG---AGELRLEEVSPDVVSQVLHYLYTSEIALD 97
           9****************************887664...5789999*****************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Ncl+++r++ l+dc +L+ aa+dfi+  F+
   Q: 131  ANCLAVFRLGLLLDCARLAVAARDFICARFP 161
           6***************************995 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTLGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRVG EREFPCHRLV LAACSPYFRA 60
RFLAEPDGAG ELRLEEVSPD VVSQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCAGTGC ACTGCCCCAC AGGAGAGCAG AGGTGTGCAG GGCAGCCCTT GACAAACAGA 60
CTTGCTGAGT TCCAGAGAGC CGCACCATGA CGCTGGGCTT GGAGCAGGCG GAGGAGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031672--C:A band
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0031674--C:I band
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031397--P:negative regulation of protein ubiquitination
GO:0016567--P:protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	86.12	0.00e+00	944.00
IUUC-Apl-003748	Anas platyrhynchos	69.76	0.00e+00	801.00
IUUC-Aca-005275	Anolis carolinensis	61.80	0.00e+00	705.00
IUUC-Acl-008133	Aspergillus clavatus	33.87	7.00e-04	38.90
IUUC-Bta-012801	Bos taurus	91.28	0.00e+00	1020.00
IUUC-Cja-019795	Callithrix jacchus	88.91	0.00e+00	952.00
IUUC-Cfa-021245	Canis familiaris	88.79	0.00e+00	783.00
IUUC-Cpo-022436	Cavia porcellus	88.01	0.00e+00	1015.00
IUUC-Csa-023105	Chlorocebus sabaeus	89.45	0.00e+00	1003.00
IUUC-Dre-028603	Danio rerio	57.17	0.00e+00	669.00
IUUC-Dno-030015	Dasypus novemcinctus	76.29	0.00e+00	645.00
IUUC-Eca-034393	Equus caballus	90.36	0.00e+00	989.00
IUUC-Fca-035823	Felis catus	79.41	0.00e+00	871.00
IUUC-Fal-037632	Ficedula albicollis	70.31	0.00e+00	787.00
IUUC-Gmo-039697	Gadus morhua	56.23	0.00e+00	656.00
IUUC-Gga-040525	Gallus gallus	70.00	0.00e+00	801.00
IUUC-Gac-042421	Gasterosteus aculeatus	59.18	0.00e+00	687.00
IUUC-Ggo-045596	Gorilla gorilla	89.09	0.00e+00	999.00
IUUC-Hsa-046235	Homo sapiens	89.09	0.00e+00	1000.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	91.62	0.00e+00	1039.00
IUUC-Lch-050123	Latimeria chalumnae	65.83	0.00e+00	773.00
IUUC-Loc-051824	Lepisosteus oculatus	63.10	0.00e+00	749.00
IUUC-Laf-053485	Loxodonta africana	86.90	0.00e+00	723.00
IUUC-Mcc-054909	Macaca mulatta	88.91	0.00e+00	1001.00
IUUC-Meu-055972	Macropus eugenii	75.26	0.00e+00	884.00
IUUC-Mga-059451	Meleagris gallopavo	70.49	0.00e+00	811.00
IUUC-Mmr-060736	Microcebus murinus	89.62	0.00e+00	1021.00
IUUC-Mdo-062563	Monodelphis domestica	77.00	0.00e+00	758.00
IUUC-Mmu-063549	Mus musculus	97.32	0.00e+00	1090.00
IUUC-Mpu-066262	Mustela putorius furo	91.10	0.00e+00	1018.00
IUUC-Mlu-067210	Myotis lucifugus	91.80	0.00e+00	1022.00
IUUC-Nle-069300	Nomascus leucogenys	89.09	0.00e+00	781.00
IUUC-Opr-070384	Ochotona princeps	84.91	0.00e+00	910.00
IUUC-Ont-071273	Oreochromis niloticus	58.29	0.00e+00	676.00
IUUC-Ocu-074499	Oryctolagus cuniculus	90.24	0.00e+00	1005.00
IUUC-Oga-088855	Otolemur garnettii	89.62	0.00e+00	1021.00
IUUC-Oar-089342	Ovis aries	77.58	0.00e+00	786.00
IUUC-Ptr-091028	Pan troglodytes	88.33	0.00e+00	774.00
IUUC-Pan-091827	Papio anubis	89.27	0.00e+00	1003.00
IUUC-Psi-092998	Pelodiscus sinensis	70.67	0.00e+00	809.00
IUUC-Pma-094586	Petromyzon marinus	58.87	3.00e-98	351.00
IUUC-Pab-097656	Pongo abelii	87.86	0.00e+00	682.00
IUUC-Pva-102331	Pteropus vampyrus	88.66	0.00e+00	967.00
IUUC-Sha-107091	Sarcophilus harrisii	76.44	0.00e+00	893.00
IUUC-Sar-112941	Sorex araneus	86.47	0.00e+00	769.00
IUUC-Ssc-116276	Sus scrofa	89.68	0.00e+00	1023.00
IUUC-Tgu-116494	Taeniopygia guttata	70.49	0.00e+00	819.00
IUUC-Tsy-119499	Tarsius syrichta	86.58	0.00e+00	652.00
IUUC-Tni-119776	Tetraodon nigroviridis	58.29	0.00e+00	681.00
IUUC-Tbe-127806	Tupaia belangeri	91.04	0.00e+00	996.00
IUUC-Ttr-128813	Tursiops truncatus	90.02	0.00e+00	1011.00
IUUC-Vpa-130127	Vicugna pacos	91.19	0.00e+00	691.00
IUUC-Xtr-132942	Xenopus tropicalis	65.95	0.00e+00	758.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence