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Tag Content
UUCD2 ID IUUC-Cfa-021071
UUCD1 version UUC-CaF-00827
Ensembl Protein ID ENSCAFP00000014378.3
UniProt Accession E2RMB0; E2RMB0_CANLF
Genbank Protein ID ENSCAFP00000014378
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03016753
Gene Name HERC3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000023804.3 ENSCAFT00000015540.4 ENSCAFP00000014378.3
ENSCAFG00000023804.3 ENSCAFT00000045241.1 ENSCAFP00000038810.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.50e-93 314.1 726 1049
Active Site
Position(s) Description Evidence
1018 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           dlkk l+v f gEe++d+gGvt+ef+ ll+kel np +g+f+y ++++  ++ +         + ++F+++G+ +g+a++++ ++dl
   Q: 726  DLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFV-----EHNWFHLIGITCGLAIYNSTVVDL 807
           899******************************************9999999776554.....579********************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll++k  ledl+e+ p+  +sl+e++++  +diee+ ++l+f++  e++g +++++L+pgG+++ V ++N++e+v+++
   Q: 808  HFPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDIEET-FCLNFTICRESYGVIEQKKLIPGGDKVTVCKDNRQEFVDAY 893
           *******************************************98.******99********************************* PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           v+y ++ +++e ++af++Gf +v+  ++l+lF+++el+ ++ G++++++++l++++ ykg+y++++p+++ Fwe+++ef  e++k+f
   Q: 894  VNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWQELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKF 980
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+a+l+   +vi+  ++ ++ lP ++TC+n+L+LP+Ysskeil   L+ A ++ +gF+l
   Q: 981  LLFLTGSDRIPIYGMASLQ---IVIQStASGEEYLPVAHTCYNLLDLPKYSSKEILSAGLTQALDNYEGFSL 1049
           *******************...8888867788**************************************97 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MLCWGYWSLG QPGISTNLQG IVAEPQVCGF ISDRSVKEVA CGGNHSVFLL EDGEVYTCGL 60
NTKGQLGHER EGNKPEQIGA LADQHIVHVA CGESHSLALS DRGQLFSWGA GSDGQLGLMT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021071|E3,HECT|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTTATGTT GGGGATATTG GTCTCTGGGC CAACCTGGGA TCAGCACCAA CCTGCAAGGG 60
ATTGTGGCTG AGCCACAGGT GTGTGGATTC ATATCTGATA GGAGTGTCAA GGAAGTGGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021071|E3,HECT|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0004842--F:ubiquitin-protein transferase activity
KEGG cfa:478475
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001673 Ailuropoda melanoleuca 99.24 0.00e+00 2100.00
IUUC-Apl-003535 Anas platyrhynchos 88.19 0.00e+00 1879.00
IUUC-Aca-005223 Anolis carolinensis 85.52 0.00e+00 1833.00
IUUC-Ame-010816 Astyanax mexicanus 66.03 0.00e+00 1163.00
IUUC-Bta-013373 Bos taurus 97.62 0.00e+00 2076.00
IUUC-Cel-018150 Caenorhabditis elegans 33.12 3.00e-154 539.00
IUUC-Cja-019609 Callithrix jacchus 98.67 0.00e+00 2096.00
IUUC-Cpo-021548 Cavia porcellus 96.76 0.00e+00 2061.00
IUUC-Csa-023987 Chlorocebus sabaeus 98.76 0.00e+00 2094.00
IUUC-Cho-024325 Choloepus hoffmanni 97.77 0.00e+00 1201.00
IUUC-Dre-027472 Danio rerio 66.25 0.00e+00 1395.00
IUUC-Dno-029241 Dasypus novemcinctus 96.67 0.00e+00 2054.00
IUUC-Dor-030672 Dipodomys ordii 91.53 0.00e+00 1129.00
IUUC-Ete-032642 Echinops telfairi 91.62 0.00e+00 1891.00
IUUC-Eca-033646 Equus caballus 98.48 0.00e+00 2089.00
IUUC-Eeu-035098 Erinaceus europaeus 84.90 0.00e+00 1379.00
IUUC-Fal-036952 Ficedula albicollis 87.90 0.00e+00 1875.00
IUUC-Gmo-039297 Gadus morhua 63.90 0.00e+00 1315.00
IUUC-Gga-040591 Gallus gallus 87.35 0.00e+00 1859.00
IUUC-Gac-041741 Gasterosteus aculeatus 65.09 0.00e+00 1380.00
IUUC-Ggo-044769 Gorilla gorilla 98.67 0.00e+00 2091.00
IUUC-Hsa-046066 Homo sapiens 98.76 0.00e+00 2095.00
IUUC-Itr-048311 Ictidomys tridecemlineatus 97.91 0.00e+00 2075.00
IUUC-Lch-050301 Latimeria chalumnae 73.81 0.00e+00 1622.00
IUUC-Loc-052803 Lepisosteus oculatus 67.25 0.00e+00 1454.00
IUUC-Laf-053364 Loxodonta africana 98.10 0.00e+00 2081.00
IUUC-Mcc-054930 Macaca mulatta 98.67 0.00e+00 2094.00
IUUC-Meu-056274 Macropus eugenii 79.08 0.00e+00 868.00
IUUC-Mtr-058277 Medicago truncatula 37.58 2.00e-52 199.00
IUUC-Mga-059563 Meleagris gallopavo 87.81 0.00e+00 1872.00
IUUC-Mmr-060792 Microcebus murinus 95.81 0.00e+00 2027.00
IUUC-Mdo-062195 Monodelphis domestica 91.25 0.00e+00 1952.00
IUUC-Mmu-063855 Mus musculus 94.95 0.00e+00 2036.00
IUUC-Mpu-066308 Mustela putorius furo 99.33 0.00e+00 2103.00
IUUC-Mlu-066927 Myotis lucifugus 98.00 0.00e+00 2075.00
IUUC-Nle-070090 Nomascus leucogenys 98.76 0.00e+00 2094.00
IUUC-Opr-070891 Ochotona princeps 85.14 0.00e+00 1761.00
IUUC-Ont-072201 Oreochromis niloticus 63.89 0.00e+00 1337.00
IUUC-Ocu-074770 Oryctolagus cuniculus 97.43 0.00e+00 2075.00
IUUC-Ola-086550 Oryzias latipes 64.96 0.00e+00 1384.00
IUUC-Olu-087836 Ostreococcus lucimarinus 34.23 6.00e-42 164.00
IUUC-Oga-088831 Otolemur garnettii 97.62 0.00e+00 2074.00
IUUC-Oar-090449 Ovis aries 97.52 0.00e+00 2071.00
IUUC-Pan-092135 Papio anubis 98.67 0.00e+00 2089.00
IUUC-Psi-093832 Pelodiscus sinensis 85.44 0.00e+00 1875.00
IUUC-Pfo-097268 Poecilia formosa 65.43 0.00e+00 1382.00
IUUC-Pab-098249 Pongo abelii 98.48 0.00e+00 2089.00
IUUC-Pca-100855 Procavia capensis 93.44 0.00e+00 1424.00
IUUC-Pva-102506 Pteropus vampyrus 89.63 0.00e+00 1840.00
IUUC-Rno-105242 Rattus norvegicus 95.24 0.00e+00 2080.00
IUUC-Sha-107186 Sarcophilus harrisii 89.24 0.00e+00 1196.00
IUUC-Sar-113612 Sorex araneus 95.65 0.00e+00 748.00
IUUC-Ssc-115473 Sus scrofa 97.52 0.00e+00 2073.00
IUUC-Tgu-116974 Taeniopygia guttata 88.11 0.00e+00 1852.00
IUUC-Tru-118077 Takifugu rubripes 63.46 0.00e+00 1316.00
IUUC-Tsy-119619 Tarsius syrichta 86.76 0.00e+00 1852.00
IUUC-Tni-120807 Tetraodon nigroviridis 63.55 0.00e+00 1337.00
IUUC-Tbe-127640 Tupaia belangeri 94.00 0.00e+00 1948.00
IUUC-Ttr-129172 Tursiops truncatus 97.05 0.00e+00 2059.00
IUUC-Vpa-130442 Vicugna pacos 83.05 0.00e+00 1698.00
IUUC-Xtr-132194 Xenopus tropicalis 71.55 0.00e+00 1441.00
Created Date 25-Jun-2017

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