iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013253

Ensembl Protein ID

ENSBTAP00000021041.5

UniProt Accession

F1MAZ5; F1MAZ5_BOVIN

Genbank Protein ID

ENSBTAP00000021041

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02003814

Gene Name

ARHGEF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000015834.5	ENSBTAT00000021041.5	ENSBTAP00000021041.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-10	40.5	197	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++l+d    +d eL +k+Gdv++v+  + ++ +W+ g    +  +G fP+nFv+
   Q: 197  EALWDHVTMDDQELGFKAGDVIEVM--DATNREWWWG--RVADGEGWFPANFVR 246
           79**********************9..9999******..89999********97 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MLWEEQPGKK PSCFQDLKAF HTEPAPGPFS TAEVGTWILP FISAEDVPRE TPSQPRRIPQ 60
HSCISLDDLW LEKTQRRKLK KQAQFERKTH AHKDGVQCWR KMIITSPKSL NLPGRSHPFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCACTTAA GGACCTTCTT GGAAGTGAGG TGAGTTACCT GTGAGTCACA TTTTTTTACC 60
TCTTAAGTAG GGACCACACA GGACATTTTC CTAAGTGTGT GGAGGGGAGG AGTAGGAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00169--PH
PF00621--RhoGEF
PF00018--SH3_1

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0030676--F:Rac guanyl-nucleotide exchange factor activity
GO:0046847--P:filopodium assembly
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

bta:505852

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002073	Ailuropoda melanoleuca	59.87	0.00e+00	688.00
IUUC-Apl-004117	Anas platyrhynchos	58.66	0.00e+00	701.00
IUUC-Aca-004793	Anolis carolinensis	59.43	0.00e+00	688.00
IUUC-Ame-010682	Astyanax mexicanus	52.97	2.00e-169	590.00
IUUC-Cja-019555	Callithrix jacchus	62.12	0.00e+00	675.00
IUUC-Cfa-020578	Canis familiaris	59.02	0.00e+00	680.00
IUUC-Csa-023331	Chlorocebus sabaeus	84.80	0.00e+00	1160.00
IUUC-Cho-025069	Choloepus hoffmanni	35.08	4.00e-54	207.00
IUUC-Cin-025453	Ciona intestinalis	49.78	9.00e-124	437.00
IUUC-Csv-025922	Ciona savignyi	46.82	4.00e-99	355.00
IUUC-Dre-028197	Danio rerio	68.99	0.00e+00	848.00
IUUC-Dno-029679	Dasypus novemcinctus	59.56	0.00e+00	669.00
IUUC-Dor-030739	Dipodomys ordii	88.14	0.00e+00	1054.00
IUUC-Ete-032545	Echinops telfairi	38.67	2.00e-45	178.00
IUUC-Eca-034299	Equus caballus	59.53	0.00e+00	679.00
IUUC-Eeu-034720	Erinaceus europaeus	34.81	2.00e-54	208.00
IUUC-Fca-036416	Felis catus	60.66	0.00e+00	635.00
IUUC-Fal-037035	Ficedula albicollis	59.06	0.00e+00	699.00
IUUC-Gmo-039587	Gadus morhua	73.27	0.00e+00	807.00
IUUC-Ggr-039728	Gaeumannomyces graminis	25.70	2.00e-11	64.70
IUUC-Gga-040841	Gallus gallus	77.74	0.00e+00	902.00
IUUC-Gac-042498	Gasterosteus aculeatus	73.33	0.00e+00	808.00
IUUC-Ggo-044700	Gorilla gorilla	35.08	7.00e-56	213.00
IUUC-Hsa-045681	Homo sapiens	60.56	0.00e+00	649.00
IUUC-Itr-048380	Ictidomys tridecemlineatus	61.94	0.00e+00	671.00
IUUC-Lch-049639	Latimeria chalumnae	68.78	0.00e+00	776.00
IUUC-Loc-051994	Lepisosteus oculatus	73.25	0.00e+00	876.00
IUUC-Laf-054307	Loxodonta africana	59.36	0.00e+00	699.00
IUUC-Mcc-055305	Macaca mulatta	64.89	1.00e-139	489.00
IUUC-Meu-056376	Macropus eugenii	62.88	0.00e+00	807.00
IUUC-Mpo-057433	Magnaporthe poae	25.40	8.00e-09	56.20
IUUC-Mga-059644	Meleagris gallopavo	58.56	0.00e+00	685.00
IUUC-Mmr-061664	Microcebus murinus	59.42	0.00e+00	649.00
IUUC-Mdo-062404	Monodelphis domestica	35.08	5.00e-56	213.00
IUUC-Mmu-063143	Mus musculus	34.81	3.00e-55	211.00
IUUC-Mpu-066851	Mustela putorius furo	60.37	0.00e+00	650.00
IUUC-Mlu-066956	Myotis lucifugus	59.70	0.00e+00	662.00
IUUC-Nle-069174	Nomascus leucogenys	44.19	3.00e-43	168.00
IUUC-Opr-070209	Ochotona princeps	62.48	0.00e+00	669.00
IUUC-Ont-072637	Oreochromis niloticus	74.90	0.00e+00	824.00
IUUC-Oan-073722	Ornithorhynchus anatinus	60.21	0.00e+00	661.00
IUUC-Ocu-074885	Oryctolagus cuniculus	59.79	0.00e+00	644.00
IUUC-Ola-087155	Oryzias latipes	34.01	2.00e-53	204.00
IUUC-Oga-088758	Otolemur garnettii	59.16	0.00e+00	673.00
IUUC-Oar-089923	Ovis aries	98.36	0.00e+00	1043.00
IUUC-Ptr-091555	Pan troglodytes	59.36	0.00e+00	695.00
IUUC-Pan-092037	Papio anubis	60.20	0.00e+00	702.00
IUUC-Psi-093865	Pelodiscus sinensis	59.19	0.00e+00	710.00
IUUC-Pfo-096918	Poecilia formosa	34.65	3.00e-53	204.00
IUUC-Pab-097910	Pongo abelii	59.87	0.00e+00	703.00
IUUC-Pca-100891	Procavia capensis	37.41	1.00e-51	198.00
IUUC-Pva-102967	Pteropus vampyrus	62.18	2.00e-150	526.00
IUUC-Rno-105479	Rattus norvegicus	37.25	3.00e-55	211.00
IUUC-Sha-107592	Sarcophilus harrisii	58.01	0.00e+00	680.00
IUUC-Sar-113369	Sorex araneus	67.21	5.00e-121	427.00
IUUC-Sre-115126	Sporisorium reilianum	27.95	2.00e-23	105.00
IUUC-Tgu-117088	Taeniopygia guttata	75.55	0.00e+00	926.00
IUUC-Tru-118716	Takifugu rubripes	36.66	1.00e-55	212.00
IUUC-Tsy-118846	Tarsius syrichta	63.61	2.00e-129	454.00
IUUC-Tni-120887	Tetraodon nigroviridis	34.39	2.00e-52	202.00
IUUC-Tme-127216	Tuber melanosporum	24.86	3.00e-23	104.00
IUUC-Tbe-127248	Tupaia belangeri	36.73	3.00e-51	198.00
IUUC-Uma-129594	Ustilago maydis	27.56	3.00e-23	104.00
IUUC-Vpa-130750	Vicugna pacos	35.53	7.00e-52	199.00
IUUC-Vvi-131436	Vitis vinifera	31.25	1.00e+00	28.50
IUUC-Xtr-132676	Xenopus tropicalis	69.57	0.00e+00	804.00
IUUC-Xma-133871	Xiphophorus maculatus	34.65	5.00e-53	203.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence