iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053977

Ensembl Protein ID

ENSLAFP00000012259.3

UniProt Accession

G3TDK8; G3TDK8_LOXAF

Protein Name

Tyrosine-protein kinase

Gene Name

SRC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000014637.3	ENSLAFT00000029208.1	ENSLAFP00000025295.1
ENSLAFG00000014637.3	ENSLAFT00000014638.3	ENSLAFP00000012259.3
ENSLAFG00000014637.3	ENSLAFT00000036975.1	ENSLAFP00000028844.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-12	47.1	88	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi....ekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ ++ +L++kkG+ ++++    + +  +++W+ + +  +g+ G +P+n+v+ 
   Q: 88   TFVALYDYESRTETDLSFKKGERLQIVnntrKVDVREGDWWLAHSLSTGQTGYIPSNYVAP 148
           5789***********************64444455689********************975 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGSNKSKPKD ASQRRRSLEP TENTHGGGGG AFPSSQTPSK PASADGHRGS NTAFAPAAAE 60
PKLFGGFNSS DTVTSPQRAG PLAGGVTTFV ALYDYESRTE TDLSFKKGER LQIVNNTRKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCAGCA ATAAGAGCAA GCCCAAGGAT GCCAGCCAGC GGCGCCGCAG CCTGGAGCCC 60
ACCGAGAACA CCCATGGTGG CGGTGGGGGA GCCTTCCCCA GCTCACAGAC CCCCAGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000140	Aegilops tauschii	30.31	3.00e-21	97.40
IUUC-Aml-001713	Ailuropoda melanoleuca	97.60	0.00e+00	1099.00
IUUC-Aca-004237	Anolis carolinensis	90.96	0.00e+00	1020.00
IUUC-Aly-005712	Arabidopsis lyrata	35.63	2.00e-19	91.30
IUUC-Ath-007146	Arabidopsis thaliana	32.28	2.00e-22	100.00
IUUC-Ame-011887	Astyanax mexicanus	78.83	0.00e+00	881.00
IUUC-Bta-012982	Bos taurus	96.35	0.00e+00	1080.00
IUUC-Bdi-014324	Brachypodium distachyon	35.11	4.00e-23	103.00
IUUC-Bol-016049	Brassica oleracea	34.68	2.00e-17	84.70
IUUC-Cja-019995	Callithrix jacchus	98.52	0.00e+00	1102.00
IUUC-Cfa-020060	Canis familiaris	97.60	0.00e+00	1099.00
IUUC-Cpo-021557	Cavia porcellus	94.28	0.00e+00	1048.00
IUUC-Csa-023711	Chlorocebus sabaeus	98.52	0.00e+00	1101.00
IUUC-Cin-025390	Ciona intestinalis	69.94	0.00e+00	665.00
IUUC-Dre-028491	Danio rerio	82.32	0.00e+00	884.00
IUUC-Dno-029651	Dasypus novemcinctus	93.48	0.00e+00	1053.00
IUUC-Ete-033170	Echinops telfairi	97.60	0.00e+00	930.00
IUUC-Eca-033970	Equus caballus	91.54	0.00e+00	996.00
IUUC-Fca-036113	Felis catus	97.60	0.00e+00	1099.00
IUUC-Fal-036785	Ficedula albicollis	94.10	0.00e+00	1062.00
IUUC-Gga-040899	Gallus gallus	92.44	0.00e+00	1039.00
IUUC-Gac-042332	Gasterosteus aculeatus	80.95	0.00e+00	890.00
IUUC-Gma-043938	Glycine max	34.34	8.00e-23	102.00
IUUC-Ggo-044829	Gorilla gorilla	84.50	0.00e+00	908.00
IUUC-Hsa-046192	Homo sapiens	98.52	0.00e+00	1101.00
IUUC-Hvu-047855	Hordeum vulgare	30.71	2.00e-22	100.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	98.15	0.00e+00	1088.00
IUUC-Lch-049892	Latimeria chalumnae	85.74	0.00e+00	957.00
IUUC-Loc-052812	Lepisosteus oculatus	81.70	0.00e+00	895.00
IUUC-Mcc-055159	Macaca mulatta	96.56	0.00e+00	1090.00
IUUC-Mtr-058733	Medicago truncatula	34.09	4.00e-23	103.00
IUUC-Mga-060135	Meleagris gallopavo	94.10	0.00e+00	1061.00
IUUC-Mmr-061168	Microcebus murinus	96.02	0.00e+00	1097.00
IUUC-Mdo-063030	Monodelphis domestica	91.68	0.00e+00	1046.00
IUUC-Mmu-063893	Mus musculus	97.60	0.00e+00	1105.00
IUUC-Mpu-066411	Mustela putorius furo	97.60	0.00e+00	1099.00
IUUC-Mlu-068139	Myotis lucifugus	98.16	0.00e+00	1098.00
IUUC-Nle-070178	Nomascus leucogenys	95.57	0.00e+00	1038.00
IUUC-Ont-072130	Oreochromis niloticus	81.67	0.00e+00	914.00
IUUC-Ocu-074403	Oryctolagus cuniculus	95.77	0.00e+00	1058.00
IUUC-Ogu-078962	Oryza glumaepatula	34.25	1.00e-23	105.00
IUUC-Oin-079172	Oryza indica	34.25	1.00e-23	105.00
IUUC-Oni-082734	Oryza nivara	34.25	2.00e-23	104.00
IUUC-Ola-086953	Oryzias latipes	82.42	0.00e+00	897.00
IUUC-Oga-088493	Otolemur garnettii	98.34	0.00e+00	1100.00
IUUC-Oar-090279	Ovis aries	96.71	0.00e+00	1082.00
IUUC-Ptr-091050	Pan troglodytes	98.52	0.00e+00	1101.00
IUUC-Pan-091862	Papio anubis	97.42	0.00e+00	1081.00
IUUC-Psi-093071	Pelodiscus sinensis	92.80	0.00e+00	1042.00
IUUC-Pfo-096578	Poecilia formosa	82.25	0.00e+00	926.00
IUUC-Pab-097902	Pongo abelii	96.75	0.00e+00	1093.00
IUUC-Pop-099554	Populus trichocarpa	32.42	2.00e-23	104.00
IUUC-Ppe-102072	Prunus persica	34.89	3.00e-26	114.00
IUUC-Pva-103176	Pteropus vampyrus	83.95	0.00e+00	922.00
IUUC-Rno-105847	Rattus norvegicus	97.79	0.00e+00	1103.00
IUUC-Sha-107539	Sarcophilus harrisii	92.62	0.00e+00	1039.00
IUUC-Stu-112331	Solanum tuberosum	32.00	2.00e-22	101.00
IUUC-Sbi-114480	Sorghum bicolor	35.78	9.00e-24	105.00
IUUC-Ssc-115762	Sus scrofa	97.63	0.00e+00	1100.00
IUUC-Tru-117849	Takifugu rubripes	81.87	0.00e+00	894.00
IUUC-Tni-120843	Tetraodon nigroviridis	80.94	0.00e+00	904.00
IUUC-Tae-123192	Triticum aestivum	30.71	7.00e-22	99.40
IUUC-Ttr-128702	Tursiops truncatus	92.99	0.00e+00	1038.00
IUUC-Vvi-131181	Vitis vinifera	33.21	4.00e-22	100.00
IUUC-Xtr-132291	Xenopus tropicalis	86.00	0.00e+00	941.00
IUUC-Xma-133134	Xiphophorus maculatus	81.88	0.00e+00	923.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence