iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-002582

Ensembl Protein ID

ERN14346

UniProt Accession

U5CMH7; U5CMH7_AMBTC

Genbank Protein ID

ERN14346.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KI392557

Gene Name

AMTR_s00033p00211330

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00033p00211330	ERN14346	ERN14346

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.50e-121	405.6	3337	3676
UBD/Alpha-Helix/UBA	2.70e-09	37.3	1315	1354

Active Site

Position(s)	Description	Evidence
3644	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykll 100
            +dlk rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf+ + ++++t+qpnp+s ++ +ehl++F+f+Gr+++kal+dg+lld+++++sfyk++
   Q: 3337 TQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVFQ-TEHLSYFKFVGRVVAKALFDGQLLDVHFTRSFYKHI 3433
           689************************************99995.55577788******985.5*********************************** PP
   S: 101  lgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.......lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqvea 192
           lg k++++d+e++dp+++k+lk+++en   d++++ ldltfsv+ ++         e++++eL+pgG+n++Vt+eNk+eYv+lv+e++l++ i+ q++a
   Q: 3434 LGAKVTYHDIEAIDPDFFKNLKWMLEN---DTSDI-LDLTFSVDADEeklilyeRTEVTDYELIPGGRNVRVTEENKHEYVDLVAEHKLTTAIRPQINA 3528
           *************************99...77777.88888876666669996666777888************************************* PP
   S: 193  freGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlf 287
           f eGfne+ip el+s+F+ +elelli+G ++id++dl+++t+y +gy++ sp+iqwFwev+++fs+e+++++LqFvTg+s++Pl+Gf++l+     ++f
   Q: 3529 FMEGFNELIPRELISIFHDKELELLISGLPDIDLDDLRANTEY-SGYSAASPVIQWFWEVVNGFSKEDKARLLQFVTGTSKVPLEGFRALQgisgSQRF 3626
           *******************************************.55*************************************************999* PP
   S: 288  virk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           +i+k ++s+d+lPs++TCfn+L+LPeY++k++l+e+Ll+Ai+e+ +gF++
   Q: 3627 QIHKaYGSPDHLPSAHTCFNQLDLPEYPTKQQLQERLLLAIHEGnEGFGF 3676
           ****999*************************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de+ +  +veMGF+r++a +aLr+   n++e+A+e+L+++
   Q: 1315 DESTISVIVEMGFSRSRAEEALRQVgTNSVEMAMEWLFSH 1354
           8999**********************************97 PP

Organism

Amborella trichopoda

Protein Sequence
(Fasta)

MGSILASPPL RLRQILSGEA TMRPSVKLDT EPPPKIKAFI DRVIKSPLSD IAIPLSGFHW 60
EYNKGNFHHW RPLFLHFDTY FKSYVCCRKD LLLSDNMTGE DALFPKHAVL QILRVMQIIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCGA TTCTAGCCAG CCCACCTTTG CGGCTGCGCC AGATTTTATC CGGCGAAGCC 60
ACCATGAGAC CCTCTGTTAA ATTGGACACT GAACCGGTAA GTTTTTTTTG TTTGAAAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

atr:18442602

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	57.60	0.00e+00	2146.00
IUUC-Apl-003400	Anas platyrhynchos	42.95	9.00e-98	349.00
IUUC-Aly-006157	Arabidopsis lyrata	58.61	0.00e+00	2286.00
IUUC-Ame-011067	Astyanax mexicanus	51.75	4.00e-125	443.00
IUUC-Bgr-012043	Blumeria graminis	33.05	2.00e-146	514.00
IUUC-Bci-013995	Botrytis cinerea	42.50	3.00e-142	500.00
IUUC-Bdi-014884	Brachypodium distachyon	59.52	0.00e+00	2247.00
IUUC-Bol-015228	Brassica oleracea	59.51	0.00e+00	1993.00
IUUC-Bra-016726	Brassica rapa	57.95	0.00e+00	2081.00
IUUC-Cpo-021766	Cavia porcellus	43.64	1.00e-100	359.00
IUUC-Cin-025627	Ciona intestinalis	50.12	1.00e-121	432.00
IUUC-Csv-025872	Ciona savignyi	50.23	2.00e-118	417.00
IUUC-Cne-027095	Cryptococcus neoformans	45.65	6.00e-105	376.00
IUUC-Cme-027267	Cyanidioschyzon merolae	52.82	8.00e-129	454.00
IUUC-Dre-028525	Danio rerio	51.15	1.00e-112	402.00
IUUC-Dse-031197	Dothistroma septosporum	40.28	1.00e-135	478.00
IUUC-Ete-032966	Echinops telfairi	43.41	2.00e-100	359.00
IUUC-Fal-036687	Ficedula albicollis	42.95	3.00e-98	352.00
IUUC-Fox-037756	Fusarium oxysporum	33.02	2.00e-157	550.00
IUUC-Gmo-039073	Gadus morhua	51.99	2.00e-126	448.00
IUUC-Gga-040845	Gallus gallus	42.95	3.00e-98	352.00
IUUC-Gac-042430	Gasterosteus aculeatus	51.99	1.00e-126	448.00
IUUC-Gma-044216	Glycine max	59.34	0.00e+00	2310.00
IUUC-Ggo-044465	Gorilla gorilla	43.31	6.00e-99	354.00
IUUC-Hvu-047697	Hordeum vulgare	58.31	0.00e+00	2199.00
IUUC-Lpe-051550	Leersia perrieri	58.35	0.00e+00	2166.00
IUUC-Meu-056751	Macropus eugenii	45.73	6.00e-77	281.00
IUUC-Mor-057201	Magnaporthe oryzae	32.60	4.00e-145	509.00
IUUC-Mpo-057597	Magnaporthe poae	40.92	6.00e-134	472.00
IUUC-Mtr-057633	Medicago truncatula	61.99	0.00e+00	4173.00
IUUC-Mla-058888	Melampsora laricipopulina	47.20	2.00e-114	404.00
IUUC-Mga-059935	Meleagris gallopavo	42.95	3.00e-98	352.00
IUUC-Mac-065499	Musa acuminata	60.88	0.00e+00	3795.00
IUUC-Oba-075757	Oryza barthii	59.17	0.00e+00	2115.00
IUUC-Obr-076553	Oryza brachyantha	59.45	0.00e+00	2202.00
IUUC-Ogl-077520	Oryza glaberrima	59.69	0.00e+00	2226.00
IUUC-Ogu-078278	Oryza glumaepatula	59.60	0.00e+00	2225.00
IUUC-Oin-079767	Oryza indica	59.18	0.00e+00	2208.00
IUUC-Olo-080380	Oryza longistaminata	58.99	0.00e+00	2211.00
IUUC-Ome-081925	Oryza meridionalis	59.64	0.00e+00	2219.00
IUUC-Oni-082619	Oryza nivara	59.69	0.00e+00	2222.00
IUUC-Opu-083684	Oryza punctata	59.18	0.00e+00	2213.00
IUUC-Oru-084501	Oryza rufipogon	59.73	0.00e+00	2229.00
IUUC-Ola-086777	Oryzias latipes	43.86	1.00e-101	363.00
IUUC-Ptr-090529	Pan troglodytes	43.41	3.00e-100	358.00
IUUC-Psi-093969	Pelodiscus sinensis	43.18	2.00e-99	355.00
IUUC-Pma-094364	Petromyzon marinus	44.90	3.00e-87	314.00
IUUC-Pfo-096232	Poecilia formosa	51.99	1.00e-126	448.00
IUUC-Pop-099468	Populus trichocarpa	63.91	0.00e+00	4317.00
IUUC-Pca-100568	Procavia capensis	43.62	2.00e-86	313.00
IUUC-Ppe-101641	Prunus persica	61.62	0.00e+00	2380.00
IUUC-Pgr-103465	Puccinia graminis	44.38	7.00e-127	449.00
IUUC-Ptt-103813	Puccinia triticina	42.17	2.00e-117	417.00
IUUC-Rno-105153	Rattus norvegicus	43.41	2.00e-100	359.00
IUUC-Spo-108024	Schizosaccharomyces pombe	43.02	2.00e-132	467.00
IUUC-Smo-109640	Selaginella moellendorffii	43.45	0.00e+00	2286.00
IUUC-Sit-110598	Setaria italica	58.90	0.00e+00	2163.00
IUUC-Sly-111706	Solanum lycopersicum	58.18	0.00e+00	2341.00
IUUC-Sbi-114042	Sorghum bicolor	57.62	0.00e+00	2104.00
IUUC-Sre-114958	Sporisorium reilianum	46.74	1.00e-144	505.00
IUUC-Tgu-117225	Taeniopygia guttata	42.73	4.00e-98	351.00
IUUC-Tru-118570	Takifugu rubripes	51.99	1.00e-126	449.00
IUUC-Tsy-119407	Tarsius syrichta	47.04	3.00e-94	338.00
IUUC-Tca-121479	Theobroma cacao	65.64	0.00e+00	4385.00
IUUC-Tvi-122370	Trichoderma virens	32.36	2.00e-147	517.00
IUUC-Tae-125214	Triticum aestivum	64.66	0.00e+00	1665.00
IUUC-Tbe-127762	Tupaia belangeri	42.78	9.00e-83	301.00
IUUC-Uma-129355	Ustilago maydis	50.62	2.00e-144	504.00
IUUC-Vvi-131078	Vitis vinifera	66.00	0.00e+00	4324.00
IUUC-Xma-133869	Xiphophorus maculatus	51.99	9.00e-127	449.00
IUUC-Yli-134657	Yarrowia lipolytica	45.90	9.00e-134	471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence