iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000014102.3	ENSMMUT00000019797.3	ENSMMUP00000018533.3
ENSMMUG00000014102.3	ENSMMUT00000062309.1	ENSMMUP00000055410.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.80e-09	37.1	186	233

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 186  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 233
           69*.*******99..*********99***********...999997.******87 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAFLAPLGRE EGIENLPCEL QRNFQLMREL DQRTEDKKAE IDILAAEYIS TVKTLSPDQR 60
VERLQKIQNA YSKCKEYSDD KVQLAMQTYE MVDKHIRRLD ADLARFEADL KDKMEGSDFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGAAGGGG ATTGTAGTAA GGAAGACCAC GTTCCCGGGG CTGGGCGAGG CTGCAGTACT 60
GCCTCTTGTC AGGTCCAGGA GGACTCAGCA GGCTGATGAG GAGGAACACA GGGCATCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	98.68	4.00e-113	400.00
IUUC-Atr-002906	Amborella trichopoda	33.33	2.00e-32	132.00
IUUC-Apl-003516	Anas platyrhynchos	89.22	2.00e-94	337.00
IUUC-Aca-005009	Anolis carolinensis	85.53	1.00e-101	362.00
IUUC-Ame-011879	Astyanax mexicanus	75.22	4.00e-94	337.00
IUUC-Bta-012590	Bos taurus	96.48	2.00e-114	404.00
IUUC-Cja-019518	Callithrix jacchus	97.82	3.00e-117	414.00
IUUC-Cfa-020620	Canis familiaris	97.38	1.00e-119	421.00
IUUC-Cpo-022085	Cavia porcellus	96.94	1.00e-112	398.00
IUUC-Csa-023421	Chlorocebus sabaeus	99.13	2.00e-114	404.00
IUUC-Dre-027588	Danio rerio	74.89	5.00e-94	337.00
IUUC-Eca-033493	Equus caballus	95.59	2.00e-115	407.00
IUUC-Fca-035635	Felis catus	98.15	2.00e-56	211.00
IUUC-Fal-036998	Ficedula albicollis	89.91	2.00e-109	387.00
IUUC-Fox-037925	Fusarium oxysporum	59.62	2.00e-19	90.50
IUUC-Gmo-039035	Gadus morhua	74.78	3.00e-90	324.00
IUUC-Gga-040578	Gallus gallus	89.08	4.00e-110	390.00
IUUC-Gac-042172	Gasterosteus aculeatus	73.04	8.00e-93	332.00
IUUC-Hsa-045965	Homo sapiens	99.13	2.00e-114	404.00
IUUC-Loc-052725	Lepisosteus oculatus	80.35	7.00e-92	329.00
IUUC-Mtr-058089	Medicago truncatula	32.39	1.00e-34	139.00
IUUC-Mga-059312	Meleagris gallopavo	89.11	9.00e-95	339.00
IUUC-Mmr-061351	Microcebus murinus	97.80	3.00e-111	394.00
IUUC-Mdo-062282	Monodelphis domestica	95.20	2.00e-108	385.00
IUUC-Mmu-063201	Mus musculus	93.45	1.00e-111	395.00
IUUC-Mpu-066302	Mustela putorius furo	97.38	8.00e-113	399.00
IUUC-Mlu-068192	Myotis lucifugus	96.07	1.00e-112	398.00
IUUC-Ont-072055	Oreochromis niloticus	74.67	2.00e-89	321.00
IUUC-Oan-073652	Ornithorhynchus anatinus	96.49	6.00e-114	402.00
IUUC-Ocu-073871	Oryctolagus cuniculus	95.22	2.00e-113	401.00
IUUC-Ola-087103	Oryzias latipes	74.03	2.00e-86	311.00
IUUC-Oga-088066	Otolemur garnettii	90.13	1.00e-96	345.00
IUUC-Ptr-091665	Pan troglodytes	99.13	2.00e-114	404.00
IUUC-Pan-091875	Papio anubis	99.13	2.00e-114	404.00
IUUC-Psi-093904	Pelodiscus sinensis	93.43	2.00e-101	361.00
IUUC-Pfo-096981	Poecilia formosa	74.78	9.00e-90	322.00
IUUC-Pva-102282	Pteropus vampyrus	90.39	4.00e-113	400.00
IUUC-Rno-105646	Rattus norvegicus	93.01	4.00e-111	393.00
IUUC-Sha-107031	Sarcophilus harrisii	96.49	6.00e-110	389.00
IUUC-Sly-111750	Solanum lycopersicum	33.20	1.00e-32	133.00
IUUC-Stu-112250	Solanum tuberosum	33.20	1.00e-32	133.00
IUUC-Tgu-116837	Taeniopygia guttata	89.47	7.00e-109	385.00
IUUC-Tru-117974	Takifugu rubripes	74.03	3.00e-86	310.00
IUUC-Tni-120024	Tetraodon nigroviridis	74.35	8.00e-80	289.00
IUUC-Tca-121597	Theobroma cacao	35.04	1.00e-31	130.00
IUUC-Vvi-131487	Vitis vinifera	33.76	7.00e-34	137.00
IUUC-Xtr-132189	Xenopus tropicalis	81.58	1.00e-99	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence