iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054017

UUCD1 version

UUC-LoA-00107

Ensembl Protein ID

ENSLAFP00000002634.2

UniProt Accession

G3SRU4; G3SRU4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000003172.2	ENSLAFT00000003172.2	ENSLAFP00000002634.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.30e-103	345.0	349	687

Active Site

Position(s)	Description	Evidence
655	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 349  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 432
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++++dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++ipV
   Q: 433  RFPPCCYKKLLSPpvvpsdqntavgicSVTIDDLCQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKIPV 519
           ************9666666666666566**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eY++l++++ l+++i +q++af+ Gf+ v+  + l l+++ee+e+l+cG++e+d+++l++ t+y+ gy +++ +i++Fw+v+ 
   Q: 520  TNQNRKEYIQLYIDFLLNKSIYKQFAAFYYGFHGVCTSNALMLLRPEEVEILVCGSPELDMHALQRSTQYE-GYAKTDLTIRYFWDVVL 607
           **********************************************************************5.5**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 608  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 687
           *****************************...9999967777**************************************985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

VRDLPPTCLD VRQKQRISID ALPSEMKASA LPEPTIPIQP KTMKDFQEDV EKVKSSGDWK 60
AVHDFYLTTF DSFPELNAAF KKDTTASFNT IEDSGVNAKF VNAVYDALLN TPQDIQKTVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGAGACC TGCCACCTAC TTGCCTTGAT GTTAGGCAAA AACAGCGCAT CTCTATAGAT 60
GCACTACCAT CCGAAATGAA GGCCTCGGCC CTTCCAGAAC CTACCATTCC TATCCAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	95.80	0.00e+00	1365.00
IUUC-Apl-003589	Anas platyrhynchos	88.06	0.00e+00	1239.00
IUUC-Aca-004350	Anolis carolinensis	82.68	0.00e+00	1181.00
IUUC-Ago-007908	Ashbya gossypii	35.06	5.00e-81	295.00
IUUC-Acl-008288	Aspergillus clavatus	35.36	2.00e-96	347.00
IUUC-Afl-008402	Aspergillus flavus	34.16	2.00e-89	323.00
IUUC-Afu-008762	Aspergillus fumigatus	34.48	2.00e-93	337.00
IUUC-Ani-009176	Aspergillus nidulans	35.22	1.00e-91	331.00
IUUC-Ang-009791	Aspergillus niger	35.37	1.00e-90	328.00
IUUC-Aor-009921	Aspergillus oryzae	34.00	6.00e-89	322.00
IUUC-Ate-010295	Aspergillus terreus	35.82	3.00e-99	357.00
IUUC-Ame-010660	Astyanax mexicanus	81.61	2.00e-152	531.00
IUUC-Bgr-011981	Blumeria graminis	32.43	5.00e-93	336.00
IUUC-Bta-012945	Bos taurus	95.05	0.00e+00	1325.00
IUUC-Bci-013697	Botrytis cinerea	32.85	3.00e-80	293.00
IUUC-Cja-019263	Callithrix jacchus	94.07	0.00e+00	1310.00
IUUC-Cfa-020486	Canis familiaris	96.90	0.00e+00	1292.00
IUUC-Cpo-021755	Cavia porcellus	95.89	0.00e+00	1353.00
IUUC-Csa-023814	Chlorocebus sabaeus	94.75	0.00e+00	1246.00
IUUC-Cho-024980	Choloepus hoffmanni	77.58	0.00e+00	1038.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.35	1.00e-95	344.00
IUUC-Dre-028551	Danio rerio	79.77	0.00e+00	1127.00
IUUC-Dno-029497	Dasypus novemcinctus	93.33	0.00e+00	1272.00
IUUC-Dor-030867	Dipodomys ordii	82.39	0.00e+00	1130.00
IUUC-Dse-031239	Dothistroma septosporum	29.14	1.00e-87	318.00
IUUC-Ete-032902	Echinops telfairi	82.94	0.00e+00	1143.00
IUUC-Eca-033678	Equus caballus	96.36	0.00e+00	1351.00
IUUC-Eeu-035262	Erinaceus europaeus	77.84	0.00e+00	1046.00
IUUC-Fca-035590	Felis catus	95.78	0.00e+00	1363.00
IUUC-Fal-037123	Ficedula albicollis	84.23	0.00e+00	1169.00
IUUC-Fox-037941	Fusarium oxysporum	40.12	5.00e-99	356.00
IUUC-Fso-038388	Fusarium solani	40.86	1.00e-101	364.00
IUUC-Gmo-039553	Gadus morhua	66.30	0.00e+00	845.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.08	1.00e-95	345.00
IUUC-Gga-040406	Gallus gallus	87.77	0.00e+00	1265.00
IUUC-Gac-042141	Gasterosteus aculeatus	76.23	0.00e+00	1107.00
IUUC-Ggo-045504	Gorilla gorilla	93.49	0.00e+00	1311.00
IUUC-Hsa-045786	Homo sapiens	94.18	0.00e+00	1315.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	89.68	0.00e+00	1227.00
IUUC-Kpa-049152	Komagataella pastoris	33.59	3.00e-74	273.00
IUUC-Lch-049824	Latimeria chalumnae	82.87	0.00e+00	1058.00
IUUC-Loc-052173	Lepisosteus oculatus	81.95	0.00e+00	1169.00
IUUC-Mcc-055713	Macaca mulatta	94.50	0.00e+00	1318.00
IUUC-Meu-056212	Macropus eugenii	68.52	7.00e-115	407.00
IUUC-Mor-057045	Magnaporthe oryzae	37.04	2.00e-88	321.00
IUUC-Mla-059187	Melampsora laricipopulina	43.52	1.00e-86	313.00
IUUC-Mga-059884	Meleagris gallopavo	80.70	0.00e+00	1111.00
IUUC-Mmr-061344	Microcebus murinus	95.34	0.00e+00	1355.00
IUUC-Mdo-062653	Monodelphis domestica	89.74	0.00e+00	1266.00
IUUC-Mmu-063775	Mus musculus	91.72	0.00e+00	1229.00
IUUC-Mpu-066069	Mustela putorius furo	96.22	0.00e+00	1318.00
IUUC-Mlu-067925	Myotis lucifugus	95.63	0.00e+00	1333.00
IUUC-Nfi-068439	Neosartorya fischeri	34.32	4.00e-93	336.00
IUUC-Ncr-068903	Neurospora crassa	37.27	2.00e-90	327.00
IUUC-Nle-070046	Nomascus leucogenys	93.78	0.00e+00	1337.00
IUUC-Opr-071085	Ochotona princeps	78.52	2.00e-135	476.00
IUUC-Ont-072126	Oreochromis niloticus	77.55	0.00e+00	1138.00
IUUC-Oan-072933	Ornithorhynchus anatinus	89.49	0.00e+00	1179.00
IUUC-Ocu-073800	Oryctolagus cuniculus	96.22	0.00e+00	1291.00
IUUC-Ola-086988	Oryzias latipes	76.56	0.00e+00	1118.00
IUUC-Oga-088117	Otolemur garnettii	96.03	0.00e+00	1122.00
IUUC-Oar-089371	Ovis aries	95.05	0.00e+00	1304.00
IUUC-Ptr-090551	Pan troglodytes	93.63	0.00e+00	1311.00
IUUC-Pan-092067	Papio anubis	95.05	0.00e+00	1324.00
IUUC-Psi-092963	Pelodiscus sinensis	87.92	0.00e+00	1219.00
IUUC-Pfo-096562	Poecilia formosa	75.84	0.00e+00	1119.00
IUUC-Pab-098680	Pongo abelii	94.61	0.00e+00	1319.00
IUUC-Pca-100986	Procavia capensis	77.17	0.00e+00	902.00
IUUC-Pva-102219	Pteropus vampyrus	85.33	0.00e+00	1028.00
IUUC-Pgr-103315	Puccinia graminis	36.97	1.00e-95	344.00
IUUC-Ptt-103736	Puccinia triticina	41.28	7.00e-93	335.00
IUUC-Rno-105270	Rattus norvegicus	91.85	0.00e+00	1238.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.25	6.00e-68	252.00
IUUC-Sha-106819	Sarcophilus harrisii	91.86	0.00e+00	1308.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.17	2.00e-84	306.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	31.51	1.00e-85	311.00
IUUC-Sar-113134	Sorex araneus	86.32	0.00e+00	1165.00
IUUC-Ssc-115441	Sus scrofa	95.78	0.00e+00	1321.00
IUUC-Tgu-117166	Taeniopygia guttata	86.73	0.00e+00	1193.00
IUUC-Tsy-118898	Tarsius syrichta	82.94	0.00e+00	1065.00
IUUC-Tre-122108	Trichoderma reesei	38.83	2.00e-88	321.00
IUUC-Tvi-122644	Trichoderma virens	39.52	1.00e-94	341.00
IUUC-Tme-127004	Tuber melanosporum	34.71	1.00e-101	365.00
IUUC-Tbe-127292	Tupaia belangeri	77.73	0.00e+00	1019.00
IUUC-Ttr-128352	Tursiops truncatus	91.41	0.00e+00	1259.00
IUUC-Vda-129969	Verticillium dahliae	40.00	3.00e-90	327.00
IUUC-Vpa-130218	Vicugna pacos	93.15	0.00e+00	927.00
IUUC-Xtr-132594	Xenopus tropicalis	80.20	0.00e+00	1100.00
IUUC-Xma-134157	Xiphophorus maculatus	75.93	0.00e+00	1048.00
IUUC-Yli-134470	Yarrowia lipolytica	30.86	3.00e-77	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence