iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053386

Ensembl Protein ID

ENSLAFP00000003196.3

UniProt Accession

G3ST53; G3ST53_LOXAF

Protein Name

Uncharacterized protein

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000003822.3	ENSLAFT00000003825.3	ENSLAFP00000003196.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	71.89	0.00e+00	1658.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MTSTGQDSTT NRQRRSRHNP HSPSHNSSVI SKRGVKKGAV PRSSPSLAEV KKKGRMKKLS 60
QAAEQDLIMG LQELPPMATQ DPEVSHPGQY GMFPLTQALF HCLWDDSFPE CSERLHAIKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCTCCA CCGGCCAAGA TTCCACCACA AACAGACAGC GAAGGAGTAG ACACAACCCC 60
CACTCACCCT CCCATAACTC CAGCGTCATC TCGGTGAGGC CCCAGACCGG CCCCGGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	40.68	8.00e-69	254.00
IUUC-Aml-002087	Ailuropoda melanoleuca	77.33	0.00e+00	1741.00
IUUC-Atr-002745	Amborella trichopoda	45.00	1.00e-82	300.00
IUUC-Aca-004303	Anolis carolinensis	56.99	0.00e+00	953.00
IUUC-Aly-006432	Arabidopsis lyrata	45.17	1.00e-77	284.00
IUUC-Ath-007355	Arabidopsis thaliana	45.48	4.00e-82	298.00
IUUC-Ago-007972	Ashbya gossypii	39.75	4.00e-75	275.00
IUUC-Acl-008187	Aspergillus clavatus	45.45	1.00e-78	288.00
IUUC-Afl-008399	Aspergillus flavus	53.95	4.00e-43	169.00
IUUC-Afu-008954	Aspergillus fumigatus	38.46	2.00e-67	250.00
IUUC-Ani-009142	Aspergillus nidulans	39.16	2.00e-72	267.00
IUUC-Ang-009522	Aspergillus niger	35.61	2.00e-39	157.00
IUUC-Aor-010069	Aspergillus oryzae	43.49	6.00e-69	255.00
IUUC-Ate-010291	Aspergillus terreus	45.70	1.00e-77	284.00
IUUC-Ame-010780	Astyanax mexicanus	45.29	0.00e+00	895.00
IUUC-Bta-013052	Bos taurus	75.66	0.00e+00	1644.00
IUUC-Bci-013789	Botrytis cinerea	40.00	4.00e-76	279.00
IUUC-Bdi-014007	Brachypodium distachyon	44.10	2.00e-81	296.00
IUUC-Bol-015468	Brassica oleracea	46.11	1.00e-81	297.00
IUUC-Bra-016680	Brassica rapa	42.82	4.00e-82	298.00
IUUC-Cel-018220	Caenorhabditis elegans	38.85	3.00e-144	506.00
IUUC-Cja-019473	Callithrix jacchus	74.57	0.00e+00	1361.00
IUUC-Cfa-020263	Canis familiaris	79.12	0.00e+00	1729.00
IUUC-Cpo-021691	Cavia porcellus	75.02	0.00e+00	1679.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	53.46	4.00e-54	204.00
IUUC-Csa-024223	Chlorocebus sabaeus	76.63	0.00e+00	1454.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	42.53	2.00e-75	276.00
IUUC-Cne-026978	Cryptococcus neoformans	44.44	1.00e-83	303.00
IUUC-Dre-028820	Danio rerio	49.73	0.00e+00	1032.00
IUUC-Dno-029160	Dasypus novemcinctus	76.42	0.00e+00	1619.00
IUUC-Dor-030859	Dipodomys ordii	68.00	0.00e+00	1541.00
IUUC-Dse-031186	Dothistroma septosporum	41.62	5.00e-75	275.00
IUUC-Dme-031963	Drosophila melanogaster	45.48	0.00e+00	663.00
IUUC-Ete-032279	Echinops telfairi	72.18	2.00e-167	582.00
IUUC-Eca-033842	Equus caballus	77.17	0.00e+00	1786.00
IUUC-Eeu-034487	Erinaceus europaeus	70.13	3.00e-144	506.00
IUUC-Fca-036430	Felis catus	78.94	0.00e+00	1712.00
IUUC-Fox-038067	Fusarium oxysporum	42.53	3.00e-74	272.00
IUUC-Fso-038263	Fusarium solani	40.10	6.00e-78	285.00
IUUC-Ggr-040062	Gaeumannomyces graminis	43.10	2.00e-76	280.00
IUUC-Gma-043738	Glycine max	47.34	2.00e-82	300.00
IUUC-Ggo-045022	Gorilla gorilla	76.35	0.00e+00	1444.00
IUUC-Hsa-046904	Homo sapiens	79.48	0.00e+00	1439.00
IUUC-Hvu-047285	Hordeum vulgare	43.93	1.00e-79	289.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	76.20	0.00e+00	1691.00
IUUC-Kpa-049281	Komagataella pastoris	39.15	3.00e-78	286.00
IUUC-Lch-050330	Latimeria chalumnae	46.89	0.00e+00	922.00
IUUC-Lpe-051214	Leersia perrieri	45.45	2.00e-82	300.00
IUUC-Lma-053263	Leptosphaeria maculans	43.81	2.00e-86	313.00
IUUC-Mcc-055530	Macaca mulatta	75.91	0.00e+00	1438.00
IUUC-Meu-056442	Macropus eugenii	67.54	0.00e+00	954.00
IUUC-Mor-057095	Magnaporthe oryzae	40.81	7.00e-78	285.00
IUUC-Mpo-057389	Magnaporthe poae	43.10	2.00e-76	280.00
IUUC-Mtr-058463	Medicago truncatula	46.25	1.00e-85	310.00
IUUC-Mla-059143	Melampsora laricipopulina	44.57	1.00e-79	291.00
IUUC-Mmr-060637	Microcebus murinus	74.40	0.00e+00	1705.00
IUUC-Mdo-062198	Monodelphis domestica	65.72	0.00e+00	1049.00
IUUC-Mmu-063346	Mus musculus	71.90	0.00e+00	1603.00
IUUC-Mac-064630	Musa acuminata	42.12	2.00e-83	303.00
IUUC-Mpu-065884	Mustela putorius furo	76.57	0.00e+00	1737.00
IUUC-Mlu-068117	Myotis lucifugus	75.59	0.00e+00	1674.00
IUUC-Nfi-068404	Neosartorya fischeri	44.65	2.00e-78	287.00
IUUC-Ncr-068672	Neurospora crassa	44.25	4.00e-77	282.00
IUUC-Nle-069868	Nomascus leucogenys	78.64	0.00e+00	663.00
IUUC-Opr-071074	Ochotona princeps	62.65	0.00e+00	954.00
IUUC-Ont-072246	Oreochromis niloticus	46.43	0.00e+00	914.00
IUUC-Oan-072911	Ornithorhynchus anatinus	61.17	2.00e-107	383.00
IUUC-Ocu-074627	Oryctolagus cuniculus	74.85	0.00e+00	1692.00
IUUC-Oba-075489	Oryza barthii	45.17	1.00e-81	297.00
IUUC-Obr-076150	Oryza brachyantha	45.31	3.00e-82	299.00
IUUC-Ogl-077437	Oryza glaberrima	45.17	7.00e-82	298.00
IUUC-Ogu-078370	Oryza glumaepatula	45.48	1.00e-82	300.00
IUUC-Oin-079210	Oryza indica	45.48	1.00e-82	300.00
IUUC-Olo-080971	Oryza longistaminata	46.55	3.00e-72	265.00
IUUC-Oni-082031	Oryza nivara	45.48	2.00e-82	300.00
IUUC-Opu-083471	Oryza punctata	45.17	6.00e-83	301.00
IUUC-Oru-084755	Oryza rufipogon	45.48	1.00e-82	300.00
IUUC-Osa-085447	Oryza sativa	45.48	1.00e-82	300.00
IUUC-Oga-089155	Otolemur garnettii	72.13	0.00e+00	1633.00
IUUC-Oar-089620	Ovis aries	75.40	0.00e+00	1628.00
IUUC-Ptr-090812	Pan troglodytes	82.10	0.00e+00	1165.00
IUUC-Pan-092340	Papio anubis	75.91	0.00e+00	1434.00
IUUC-Pma-094386	Petromyzon marinus	54.10	0.00e+00	789.00
IUUC-Pno-095131	Phaeosphaeria nodorum	44.97	5.00e-72	265.00
IUUC-Ppa-095550	Physcomitrella patens	47.38	7.00e-86	311.00
IUUC-Pfo-096110	Poecilia formosa	48.54	0.00e+00	850.00
IUUC-Pab-098422	Pongo abelii	78.20	0.00e+00	1408.00
IUUC-Pop-099174	Populus trichocarpa	43.61	3.00e-80	293.00
IUUC-Pca-100833	Procavia capensis	84.36	0.00e+00	1732.00
IUUC-Ppe-101644	Prunus persica	44.72	1.00e-84	306.00
IUUC-Pva-102410	Pteropus vampyrus	71.79	0.00e+00	1561.00
IUUC-Ptt-103841	Puccinia triticina	39.80	5.00e-77	282.00
IUUC-Pte-104383	Pyrenophora teres	42.38	2.00e-80	293.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	42.64	5.00e-81	295.00
IUUC-Rno-105131	Rattus norvegicus	71.55	0.00e+00	1591.00
IUUC-Sce-106274	Saccharomyces cerevisiae	38.59	5.00e-77	282.00
IUUC-Sha-106661	Sarcophilus harrisii	54.60	0.00e+00	785.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	41.73	3.00e-83	302.00
IUUC-Spo-108300	Schizosaccharomyces pombe	45.65	6.00e-84	305.00
IUUC-Smo-109615	Selaginella moellendorffii	47.71	8.00e-84	304.00
IUUC-Sit-110160	Setaria italica	45.14	1.00e-77	283.00
IUUC-Sly-111164	Solanum lycopersicum	42.37	6.00e-78	285.00
IUUC-Stu-112685	Solanum tuberosum	41.96	6.00e-65	241.00
IUUC-Sar-113692	Sorex araneus	63.06	0.00e+00	728.00
IUUC-Sbi-114301	Sorghum bicolor	45.48	6.00e-78	285.00
IUUC-Sre-115013	Sporisorium reilianum	43.05	2.00e-79	290.00
IUUC-Ssc-115724	Sus scrofa	77.26	0.00e+00	1609.00
IUUC-Tgu-116605	Taeniopygia guttata	48.91	0.00e+00	688.00
IUUC-Tru-117614	Takifugu rubripes	57.72	0.00e+00	838.00
IUUC-Tsy-118807	Tarsius syrichta	73.85	0.00e+00	808.00
IUUC-Tni-119809	Tetraodon nigroviridis	54.87	0.00e+00	776.00
IUUC-Tca-121312	Theobroma cacao	45.60	2.00e-83	303.00
IUUC-Tre-121930	Trichoderma reesei	41.49	4.00e-80	292.00
IUUC-Tvi-122373	Trichoderma virens	40.19	1.00e-78	287.00
IUUC-Tae-123064	Triticum aestivum	42.19	2.00e-74	272.00
IUUC-Tme-127027	Tuber melanosporum	40.52	3.00e-68	252.00
IUUC-Tbe-127675	Tupaia belangeri	84.76	5.00e-74	273.00
IUUC-Ttr-128411	Tursiops truncatus	75.13	0.00e+00	1681.00
IUUC-Uma-129408	Ustilago maydis	46.10	1.00e-74	273.00
IUUC-Vda-129994	Verticillium dahliae	41.67	6.00e-70	258.00
IUUC-Vpa-130525	Vicugna pacos	73.94	7.00e-57	215.00
IUUC-Vvi-131038	Vitis vinifera	43.75	4.00e-83	302.00
IUUC-Xtr-132618	Xenopus tropicalis	52.74	0.00e+00	917.00
IUUC-Xma-133730	Xiphophorus maculatus	48.99	0.00e+00	688.00
IUUC-Yli-134680	Yarrowia lipolytica	41.71	8.00e-82	298.00
IUUC-Zma-135110	Zea mays	45.00	1.00e-78	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence