iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035773

Ensembl Protein ID

ENSFCAP00000013844.3

UniProt Accession

M3WLL9; M3WLL9_FELCA

Genbank Protein ID

ENSFCAP00000013844

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02019420

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000014924.3	ENSFCAT00000014928.3	ENSFCAP00000013844.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.18	0.00e+00	1965.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

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Nucleotide Sequence
(Fasta)

TTCTGTTTGT TTTCCAGGTT ATATTTCACA CTATGTGCTG ACTGTATCTA CGGAAGATAT 60
TTAAAAAAAA AAACTTTTTT CAAAGATTTT GATTCCAGTG GAATCTTTGC TTTAGATTAT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	97.53	0.00e+00	1961.00
IUUC-Apl-003290	Anas platyrhynchos	87.26	0.00e+00	1849.00
IUUC-Aca-004905	Anolis carolinensis	84.45	0.00e+00	1717.00
IUUC-Ame-011475	Astyanax mexicanus	77.56	0.00e+00	913.00
IUUC-Cja-019907	Callithrix jacchus	97.27	0.00e+00	2011.00
IUUC-Cfa-020679	Canis familiaris	97.35	0.00e+00	1962.00
IUUC-Cpo-022110	Cavia porcellus	91.91	0.00e+00	1935.00
IUUC-Csa-024166	Chlorocebus sabaeus	97.33	0.00e+00	1933.00
IUUC-Dno-029870	Dasypus novemcinctus	94.70	0.00e+00	967.00
IUUC-Dor-030934	Dipodomys ordii	87.15	0.00e+00	1481.00
IUUC-Dme-031708	Drosophila melanogaster	64.72	1.00e-162	566.00
IUUC-Ete-032652	Echinops telfairi	96.53	0.00e+00	1389.00
IUUC-Eca-033236	Equus caballus	96.47	0.00e+00	1925.00
IUUC-Eeu-035091	Erinaceus europaeus	83.12	0.00e+00	875.00
IUUC-Fal-036972	Ficedula albicollis	85.85	0.00e+00	1822.00
IUUC-Gmo-039303	Gadus morhua	79.73	0.00e+00	887.00
IUUC-Ggo-044691	Gorilla gorilla	90.78	0.00e+00	1842.00
IUUC-Hsa-046163	Homo sapiens	97.18	0.00e+00	2008.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	93.84	0.00e+00	1045.00
IUUC-Lch-050667	Latimeria chalumnae	74.09	0.00e+00	1519.00
IUUC-Loc-052404	Lepisosteus oculatus	69.40	0.00e+00	1325.00
IUUC-Laf-053618	Loxodonta africana	97.09	0.00e+00	1897.00
IUUC-Mcc-054692	Macaca mulatta	97.35	0.00e+00	2012.00
IUUC-Meu-056025	Macropus eugenii	84.93	0.00e+00	922.00
IUUC-Mmr-061188	Microcebus murinus	96.91	0.00e+00	1950.00
IUUC-Mdo-063035	Monodelphis domestica	92.25	0.00e+00	1882.00
IUUC-Mmu-064146	Mus musculus	92.77	0.00e+00	1902.00
IUUC-Mpu-066217	Mustela putorius furo	97.27	0.00e+00	1953.00
IUUC-Mlu-068023	Myotis lucifugus	95.50	0.00e+00	1947.00
IUUC-Nle-069506	Nomascus leucogenys	97.09	0.00e+00	2011.00
IUUC-Opr-070587	Ochotona princeps	83.04	0.00e+00	1589.00
IUUC-Ont-071278	Oreochromis niloticus	77.83	0.00e+00	887.00
IUUC-Oan-073500	Ornithorhynchus anatinus	91.35	0.00e+00	1921.00
IUUC-Ocu-074299	Oryctolagus cuniculus	96.15	0.00e+00	1836.00
IUUC-Ola-086665	Oryzias latipes	78.49	0.00e+00	902.00
IUUC-Oga-088519	Otolemur garnettii	89.79	0.00e+00	1743.00
IUUC-Oar-089246	Ovis aries	96.67	0.00e+00	1847.00
IUUC-Ptr-091102	Pan troglodytes	97.27	0.00e+00	2011.00
IUUC-Pan-091952	Papio anubis	97.18	0.00e+00	2014.00
IUUC-Pfo-097227	Poecilia formosa	61.36	0.00e+00	1147.00
IUUC-Pab-097975	Pongo abelii	93.92	0.00e+00	1915.00
IUUC-Pca-101127	Procavia capensis	92.01	0.00e+00	1314.00
IUUC-Pva-102431	Pteropus vampyrus	87.92	0.00e+00	1732.00
IUUC-Sha-106690	Sarcophilus harrisii	91.20	0.00e+00	1871.00
IUUC-Ssc-116189	Sus scrofa	97.27	0.00e+00	1899.00
IUUC-Tgu-116527	Taeniopygia guttata	86.84	0.00e+00	1833.00
IUUC-Tru-118389	Takifugu rubripes	61.92	0.00e+00	1198.00
IUUC-Tsy-119193	Tarsius syrichta	93.74	0.00e+00	1886.00
IUUC-Tni-119790	Tetraodon nigroviridis	80.49	0.00e+00	870.00
IUUC-Tbe-127445	Tupaia belangeri	90.69	0.00e+00	1527.00
IUUC-Ttr-128877	Tursiops truncatus	96.83	0.00e+00	1895.00
IUUC-Xtr-132274	Xenopus tropicalis	77.87	0.00e+00	1582.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence