iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106690

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01155889

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000007589.1	ENSSHAT00000008835.1	ENSSHAP00000008762.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.45	0.00e+00	1914.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGTTATA TTTCACACTA TGTGCTGACT GTATTTACAG AAGATATTTA AAAAGCAAAC 60
AAACTTTTTT TTTTTTGAAA GAATTTGATT CCAGTGGAAT CTGTGCTTTA GATTTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

KEGG

shr:100926303

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	91.28	0.00e+00	1837.00
IUUC-Apl-003290	Anas platyrhynchos	85.35	0.00e+00	1786.00
IUUC-Aca-004905	Anolis carolinensis	83.61	0.00e+00	1753.00
IUUC-Ame-011475	Astyanax mexicanus	78.57	0.00e+00	912.00
IUUC-Cja-019907	Callithrix jacchus	91.01	0.00e+00	1883.00
IUUC-Cfa-020679	Canis familiaris	90.57	0.00e+00	1797.00
IUUC-Cpo-022110	Cavia porcellus	87.26	0.00e+00	1840.00
IUUC-Csa-024166	Chlorocebus sabaeus	91.70	0.00e+00	1813.00
IUUC-Dno-029870	Dasypus novemcinctus	87.78	0.00e+00	873.00
IUUC-Dor-030934	Dipodomys ordii	82.27	0.00e+00	1382.00
IUUC-Dme-031708	Drosophila melanogaster	64.51	2.00e-162	565.00
IUUC-Ete-032652	Echinops telfairi	91.73	0.00e+00	1295.00
IUUC-Eca-033236	Equus caballus	90.66	0.00e+00	1786.00
IUUC-Eeu-035091	Erinaceus europaeus	82.19	0.00e+00	865.00
IUUC-Fca-035773	Felis catus	91.20	0.00e+00	1806.00
IUUC-Fal-036972	Ficedula albicollis	84.89	0.00e+00	1799.00
IUUC-Gmo-039303	Gadus morhua	79.59	0.00e+00	890.00
IUUC-Ggo-044691	Gorilla gorilla	85.98	0.00e+00	1732.00
IUUC-Hsa-046163	Homo sapiens	91.45	0.00e+00	1890.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	84.62	0.00e+00	917.00
IUUC-Lch-050667	Latimeria chalumnae	74.70	0.00e+00	1534.00
IUUC-Loc-052404	Lepisosteus oculatus	69.68	0.00e+00	1320.00
IUUC-Laf-053618	Loxodonta africana	91.82	0.00e+00	1764.00
IUUC-Mcc-054692	Macaca mulatta	91.19	0.00e+00	1882.00
IUUC-Meu-056025	Macropus eugenii	95.21	0.00e+00	1061.00
IUUC-Mmr-061188	Microcebus murinus	91.37	0.00e+00	1816.00
IUUC-Mdo-063035	Monodelphis domestica	97.71	0.00e+00	2016.00
IUUC-Mmu-064146	Mus musculus	88.27	0.00e+00	1828.00
IUUC-Mpu-066217	Mustela putorius furo	90.13	0.00e+00	1796.00
IUUC-Mlu-068023	Myotis lucifugus	90.22	0.00e+00	1803.00
IUUC-Nle-069506	Nomascus leucogenys	91.28	0.00e+00	1885.00
IUUC-Opr-070587	Ochotona princeps	78.11	0.00e+00	1471.00
IUUC-Ont-071278	Oreochromis niloticus	61.87	0.00e+00	1185.00
IUUC-Oan-073500	Ornithorhynchus anatinus	90.65	0.00e+00	1950.00
IUUC-Ocu-074299	Oryctolagus cuniculus	90.53	0.00e+00	1708.00
IUUC-Ola-086665	Oryzias latipes	62.38	0.00e+00	1223.00
IUUC-Oga-088519	Otolemur garnettii	84.34	0.00e+00	1619.00
IUUC-Oar-089246	Ovis aries	90.62	0.00e+00	1716.00
IUUC-Ptr-091102	Pan troglodytes	91.37	0.00e+00	1886.00
IUUC-Pan-091952	Papio anubis	91.12	0.00e+00	1880.00
IUUC-Pfo-097227	Poecilia formosa	62.55	0.00e+00	1171.00
IUUC-Pab-097975	Pongo abelii	88.37	0.00e+00	1802.00
IUUC-Pca-101127	Procavia capensis	85.18	0.00e+00	1181.00
IUUC-Pva-102431	Pteropus vampyrus	82.64	0.00e+00	1603.00
IUUC-Ssc-116189	Sus scrofa	91.20	0.00e+00	1768.00
IUUC-Tgu-116527	Taeniopygia guttata	85.54	0.00e+00	1800.00
IUUC-Tru-118389	Takifugu rubripes	62.32	0.00e+00	1213.00
IUUC-Tsy-119193	Tarsius syrichta	88.72	0.00e+00	1752.00
IUUC-Tni-119790	Tetraodon nigroviridis	79.01	0.00e+00	872.00
IUUC-Tbe-127445	Tupaia belangeri	93.19	0.00e+00	1238.00
IUUC-Ttr-128877	Tursiops truncatus	90.58	0.00e+00	1759.00
IUUC-Xtr-132274	Xenopus tropicalis	78.15	0.00e+00	1591.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence