iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000010157.2	ENSCJAT00000019776.1	ENSCJAP00000018723.1
ENSCJAG00000010157.2	ENSCJAT00000057693.1	ENSCJAP00000042664.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-71	240.4	69	502

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ +++++++ +++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPAFIKWLEEFTTQYTRDQKEPPSHQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISSF 157
           9*****************************7777778888889999*************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e+++e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQSEitpkqitcrtRGSPHPTSNHWKSQHPFHGRLTSNMICKHCEHQSpVR 244
           *******************9..668888889998888888888999999999999********************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 245  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgtlngekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 330
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts...........peekqke........................................... 274
           s++ + + k +++v+f++ L ++ +  +           +     +                                           
   Q: 331  SSH-GTPLKRHEHVQFNEFLMMDIYKYHllghkpsqhnpK-----Klnknpgptlelqdgpaaptpvlnqpgapktqifmngtcspsll 413
           998.8888*********88877755444456665555550.....04455566666666666666666666666666777777777777 PP
   S: 275  ....................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlf 334
                               ++ ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+lf
   Q: 414  ptlsapmpfplpivpdysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppsarnplsTSNQWLWVSDDTVRKASLQEVLS---SSAYLLF 499
           777777777777777777669999***********************9999988888999*******************...******* PP
   S: 335  Ykr 337
           Y+r
   Q: 500  YER 502
           *98 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MLSSRAEAAL TAADRAIQRF LRTGAAVRYK VMKNWGVIGG IAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP AFIKWLEEFT TQYTRDQKEP PSHQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGAGCT CCCGGGCCGA GGCGGCGCTG ACTGCGGCTG ACAGGGCCAT CCAGCGCTTC 60
CTGCGTACCG GAGCGGCTGT CAGGTGAGCT TTTGGGGGGC GGGGCGGCCG AAGAGGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	28.71	3.00e-16	79.70
IUUC-Aml-001733	Ailuropoda melanoleuca	93.09	0.00e+00	879.00
IUUC-Atr-002510	Amborella trichopoda	24.04	4.00e-20	92.80
IUUC-Apl-003645	Anas platyrhynchos	71.53	3.00e-107	381.00
IUUC-Aca-004583	Anolis carolinensis	68.42	1.00e-24	103.00
IUUC-Aly-005754	Arabidopsis lyrata	25.21	1.00e-23	104.00
IUUC-Ath-007622	Arabidopsis thaliana	27.07	2.00e-24	107.00
IUUC-Ame-010896	Astyanax mexicanus	61.75	3.00e-155	541.00
IUUC-Bgr-012133	Blumeria graminis	22.80	3.00e-10	60.80
IUUC-Bta-012321	Bos taurus	91.89	0.00e+00	865.00
IUUC-Bci-013590	Botrytis cinerea	21.86	9.00e-13	68.90
IUUC-Bdi-014795	Brachypodium distachyon	27.97	8.00e-18	85.10
IUUC-Bol-015637	Brassica oleracea	26.54	2.00e-23	103.00
IUUC-Bra-016801	Brassica rapa	26.43	4.00e-23	102.00
IUUC-Cel-018308	Caenorhabditis elegans	27.67	1.00e-36	147.00
IUUC-Cfa-021206	Canis familiaris	91.17	0.00e+00	883.00
IUUC-Cpo-021343	Cavia porcellus	93.03	0.00e+00	865.00
IUUC-Csa-023419	Chlorocebus sabaeus	98.46	0.00e+00	972.00
IUUC-Cho-024475	Choloepus hoffmanni	88.41	4.00e-138	484.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.12	5.00e-12	66.20
IUUC-Cne-027061	Cryptococcus neoformans	24.33	6.00e-10	59.70
IUUC-Dre-027563	Danio rerio	59.55	5.00e-159	554.00
IUUC-Dno-029929	Dasypus novemcinctus	93.24	0.00e+00	912.00
IUUC-Dor-030166	Dipodomys ordii	83.01	0.00e+00	756.00
IUUC-Dme-031627	Drosophila melanogaster	34.71	1.00e-35	144.00
IUUC-Ete-032634	Echinops telfairi	80.50	0.00e+00	700.00
IUUC-Eca-033968	Equus caballus	93.28	0.00e+00	847.00
IUUC-Eeu-035279	Erinaceus europaeus	81.71	2.00e-58	220.00
IUUC-Fca-036525	Felis catus	94.21	0.00e+00	909.00
IUUC-Fal-036606	Ficedula albicollis	74.09	1.00e-160	559.00
IUUC-Gmo-038726	Gadus morhua	56.88	8.00e-144	503.00
IUUC-Gga-040718	Gallus gallus	74.56	2.00e-161	561.00
IUUC-Gac-042645	Gasterosteus aculeatus	57.46	2.00e-151	528.00
IUUC-Gma-042890	Glycine max	25.66	6.00e-26	112.00
IUUC-Ggo-045021	Gorilla gorilla	98.07	0.00e+00	967.00
IUUC-Hsa-045832	Homo sapiens	98.07	0.00e+00	967.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	94.91	0.00e+00	870.00
IUUC-Lch-050662	Latimeria chalumnae	69.98	3.00e-180	624.00
IUUC-Lpe-051078	Leersia perrieri	26.68	4.00e-31	129.00
IUUC-Loc-052611	Lepisosteus oculatus	65.69	2.00e-178	619.00
IUUC-Lma-053048	Leptosphaeria maculans	20.32	2.00e-15	77.80
IUUC-Laf-053752	Loxodonta africana	92.46	0.00e+00	842.00
IUUC-Mcc-054892	Macaca mulatta	98.46	0.00e+00	972.00
IUUC-Meu-056673	Macropus eugenii	74.55	2.00e-163	568.00
IUUC-Mor-057143	Magnaporthe oryzae	20.25	3.00e-08	53.50
IUUC-Mtr-057976	Medicago truncatula	26.32	7.00e-33	135.00
IUUC-Mla-058970	Melampsora laricipopulina	22.44	3.00e-19	90.10
IUUC-Mga-059543	Meleagris gallopavo	76.04	0.00e+00	668.00
IUUC-Mmr-061534	Microcebus murinus	95.17	0.00e+00	912.00
IUUC-Mdo-062140	Monodelphis domestica	67.85	3.00e-167	581.00
IUUC-Mmu-063673	Mus musculus	89.58	0.00e+00	852.00
IUUC-Mpu-066328	Mustela putorius furo	92.28	0.00e+00	867.00
IUUC-Mlu-067938	Myotis lucifugus	92.86	0.00e+00	914.00
IUUC-Nle-069426	Nomascus leucogenys	97.29	0.00e+00	867.00
IUUC-Opr-070796	Ochotona princeps	84.88	1.00e-123	436.00
IUUC-Ont-072248	Oreochromis niloticus	58.19	2.00e-157	548.00
IUUC-Oan-072916	Ornithorhynchus anatinus	79.96	0.00e+00	776.00
IUUC-Ocu-074459	Oryctolagus cuniculus	86.70	0.00e+00	669.00
IUUC-Oba-075765	Oryza barthii	26.95	5.00e-30	125.00
IUUC-Obr-076005	Oryza brachyantha	26.98	4.00e-31	129.00
IUUC-Ogl-077916	Oryza glaberrima	27.79	9.00e-34	138.00
IUUC-Ogu-078263	Oryza glumaepatula	27.34	7.00e-31	128.00
IUUC-Oin-080096	Oryza indica	28.03	1.00e-24	107.00
IUUC-Ome-081928	Oryza meridionalis	27.40	5.00e-32	132.00
IUUC-Oni-082424	Oryza nivara	27.34	6.00e-31	128.00
IUUC-Oru-085117	Oryza rufipogon	27.34	6.00e-31	128.00
IUUC-Ola-087429	Oryzias latipes	57.06	4.00e-149	521.00
IUUC-Oga-087981	Otolemur garnettii	94.98	0.00e+00	902.00
IUUC-Oar-089927	Ovis aries	91.31	0.00e+00	860.00
IUUC-Ptr-090878	Pan troglodytes	98.07	0.00e+00	967.00
IUUC-Pan-092698	Papio anubis	98.46	0.00e+00	972.00
IUUC-Psi-093451	Pelodiscus sinensis	77.08	0.00e+00	723.00
IUUC-Ppa-096015	Physcomitrella patens	25.12	8.00e-10	58.90
IUUC-Pfo-096096	Poecilia formosa	58.65	4.00e-155	541.00
IUUC-Pab-098676	Pongo abelii	97.10	0.00e+00	948.00
IUUC-Pca-100418	Procavia capensis	96.55	1.00e-131	462.00
IUUC-Ppe-101898	Prunus persica	24.90	3.00e-24	106.00
IUUC-Pva-103018	Pteropus vampyrus	92.08	0.00e+00	886.00
IUUC-Pgr-103423	Puccinia graminis	26.67	6.00e-10	60.10
IUUC-Pte-104330	Pyrenophora teres	21.53	1.00e-14	75.10
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.40	3.00e-16	80.50
IUUC-Rno-105708	Rattus norvegicus	88.61	0.00e+00	841.00
IUUC-Sha-106971	Sarcophilus harrisii	79.58	0.00e+00	783.00
IUUC-Sit-110442	Setaria italica	27.07	1.00e-27	117.00
IUUC-Sly-110928	Solanum lycopersicum	24.08	2.00e-15	77.00
IUUC-Stu-112223	Solanum tuberosum	25.21	5.00e-17	82.40
IUUC-Ssc-116397	Sus scrofa	91.51	0.00e+00	863.00
IUUC-Tgu-117446	Taeniopygia guttata	70.04	0.00e+00	644.00
IUUC-Tru-118268	Takifugu rubripes	58.37	2.00e-143	501.00
IUUC-Tsy-119484	Tarsius syrichta	91.34	3.00e-53	202.00
IUUC-Tni-119735	Tetraodon nigroviridis	53.41	9.00e-123	433.00
IUUC-Tca-121660	Theobroma cacao	24.62	3.00e-28	119.00
IUUC-Tae-125203	Triticum aestivum	27.69	4.00e-28	119.00
IUUC-Tur-126458	Triticum urartu	27.97	3.00e-26	112.00
IUUC-Tbe-127740	Tupaia belangeri	88.22	0.00e+00	811.00
IUUC-Ttr-129273	Tursiops truncatus	90.15	0.00e+00	846.00
IUUC-Vvi-131177	Vitis vinifera	25.97	4.00e-28	119.00
IUUC-Xtr-132374	Xenopus tropicalis	65.66	4.00e-174	604.00
IUUC-Xma-133267	Xiphophorus maculatus	61.17	1.00e-157	549.00
IUUC-Yli-134571	Yarrowia lipolytica	24.31	3.00e-12	67.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence