iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Smo-109428

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-protein ligase, UPL1

Genbank Nucleotide ID

GL377661

Gene Name

UPL1-1; SELMODRAFT_160088

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_160088	EFJ09581	EFJ09581

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.70e-120	402.5	3207	3545
UBD/Alpha-Helix/UBA	3.00e-07	31.1	1256	1295

Active Site

Position(s)	Description	Evidence
3513	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           +++k rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf+ + ++++t+qpnp+s ++ +ehl++F+f+Gr++ kal+dg+lld+ +++sfyk++l
   Q: 3207 DEVKGRLTVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVYQ-TEHLSYFKFVGRVVSKALFDGQLLDVYFTRSFYKHIL 3303
           67899*********************************99995.55577788******986.5************************************ PP
   S: 102  gkklsledleevdpelykslkeikenaesdieelgldltfsvseei.......lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveaf 193
           g+k++++d+e+vdp++yk+lk+++en   d++++ l ltfs++ ++         e++++eL+pgG+ni+Vt+eNk+eYv+l++e+rl++ i+ q++af
   Q: 3304 GTKVTYHDIEAVDPDYYKNLKWLLEN---DVNDI-LGLTFSIDADEekhilyeKTEVTDHELVPGGRNIRVTEENKHEYVDLIAEHRLTTAIRPQINAF 3398
           ************************99...77776.77777766555568895555566778************************************** PP
   S: 194  reGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfv 288
            eGfne++p el+s+F+ +elelli+G +eid++dl+++t+y+g y++ sp++qwFwev+++fs+e+ +++LqF+Tg+s++Pl+Gf++l+    p++f+
   Q: 3399 LEGFNELVPRELISIFNDKELELLISGLPEIDLDDLRANTEYTG-YSSGSPVVQWFWEVVQDFSKEDMARLLQFITGTSKVPLEGFKALQgisgPQKFQ 3496
           ******************************************66.****************************************************** PP
   S: 289  irk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           i+k +++++rlPs++TCfn+L+LPeYssk++++++Ll+Ai+e+ +gF++
   Q: 3497 IHKaYGAPERLPSAHTCFNQLDLPEYSSKDQMHDRLLLAIHEAsEGFGF 3545
           ***99999***********************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de ++  ++eMGF+r +a  aLr++   ++e A+e+L+++
   Q: 1256 DEALISTIMEMGFPRARAEAALRNSeASSVELAMEWLFTH 1295
           7889**********************************98 PP

Organism

Selaginella moellendorffii

Protein Sequence
(Fasta)

MKVKRKRGAE TPPRIRSFIN NVVSTPLESI HTVLSSFYWD FEKGDFFHWL DLINHFDSFL 60
EKFVTSRKDL QLDLEGSDES DVPKEAVLQV LRVTRCLLDN CVNRSFYNSL EHLTVLLAST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGTGA AGAGGAAGAG AGGCGCGGAG ACGGTAAGCT TTTGGATTCT CGCCCGCGCT 60
TCGGCTGCTT TGCATGCCTC TATAGTTCTT AGGGTTCTGT GTCCGGATTG AGCTGAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00185--ARM
SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

smo:SELMODRAFT_160088

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	46.73	0.00e+00	1045.00
IUUC-Aml-001684	Ailuropoda melanoleuca	53.04	3.00e-130	461.00
IUUC-Aly-006083	Arabidopsis lyrata	43.99	0.00e+00	1439.00
IUUC-Ath-007472	Arabidopsis thaliana	42.25	0.00e+00	1569.00
IUUC-Afl-008712	Aspergillus flavus	34.47	4.00e-147	514.00
IUUC-Ang-009771	Aspergillus niger	33.50	1.00e-141	498.00
IUUC-Aor-010186	Aspergillus oryzae	40.53	2.00e-128	452.00
IUUC-Ame-011067	Astyanax mexicanus	52.56	3.00e-128	454.00
IUUC-Bta-012813	Bos taurus	53.16	3.00e-130	461.00
IUUC-Bci-013995	Botrytis cinerea	40.86	9.00e-141	496.00
IUUC-Bdi-014884	Brachypodium distachyon	49.80	0.00e+00	1147.00
IUUC-Bra-016637	Brassica rapa	43.50	0.00e+00	1381.00
IUUC-Cel-018179	Caenorhabditis elegans	48.03	9.00e-121	429.00
IUUC-Cja-018741	Callithrix jacchus	53.27	1.00e-129	458.00
IUUC-Cfa-020083	Canis familiaris	53.16	3.00e-130	461.00
IUUC-Csa-023853	Chlorocebus sabaeus	53.16	2.00e-130	461.00
IUUC-Cho-024718	Choloepus hoffmanni	53.93	1.00e-118	422.00
IUUC-Cin-025627	Ciona intestinalis	50.46	3.00e-125	444.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	40.24	1.00e-140	495.00
IUUC-Dre-028525	Danio rerio	51.78	3.00e-115	410.00
IUUC-Dno-029680	Dasypus novemcinctus	52.76	3.00e-130	461.00
IUUC-Dor-030902	Dipodomys ordii	47.18	2.00e-110	395.00
IUUC-Dse-031197	Dothistroma septosporum	35.60	4.00e-136	480.00
IUUC-Dme-032122	Drosophila melanogaster	48.08	3.00e-124	441.00
IUUC-Eca-033915	Equus caballus	52.35	1.00e-127	452.00
IUUC-Eeu-034963	Erinaceus europaeus	52.68	3.00e-128	454.00
IUUC-Fca-035824	Felis catus	53.04	3.00e-130	461.00
IUUC-Fox-037756	Fusarium oxysporum	40.92	1.00e-143	505.00
IUUC-Gmo-039073	Gadus morhua	52.80	1.00e-129	459.00
IUUC-Ggr-039946	Gaeumannomyces graminis	39.91	6.00e-138	486.00
IUUC-Gac-042430	Gasterosteus aculeatus	52.80	1.00e-129	459.00
IUUC-Gma-043497	Glycine max	49.43	0.00e+00	1176.00
IUUC-Hsa-046879	Homo sapiens	53.16	3.00e-130	461.00
IUUC-Hvu-047697	Hordeum vulgare	48.98	0.00e+00	1139.00
IUUC-Loc-052472	Lepisosteus oculatus	53.27	2.00e-130	461.00
IUUC-Lma-053159	Leptosphaeria maculans	33.22	3.00e-145	510.00
IUUC-Laf-054154	Loxodonta africana	53.04	3.00e-130	461.00
IUUC-Mor-057201	Magnaporthe oryzae	40.24	7.00e-139	489.00
IUUC-Mtr-058128	Medicago truncatula	45.68	0.00e+00	2509.00
IUUC-Mvi-060320	Microbotryum violaceum	50.12	1.00e-129	459.00
IUUC-Mmr-060820	Microcebus murinus	53.04	2.00e-130	461.00
IUUC-Mdo-062930	Monodelphis domestica	53.04	1.00e-130	462.00
IUUC-Mmu-063601	Mus musculus	52.76	2.00e-130	461.00
IUUC-Mac-065557	Musa acuminata	57.22	0.00e+00	1072.00
IUUC-Mlu-067418	Myotis lucifugus	53.16	2.00e-130	461.00
IUUC-Nle-069418	Nomascus leucogenys	53.16	3.00e-130	461.00
IUUC-Opr-070443	Ochotona princeps	44.64	1.00e-94	341.00
IUUC-Ont-071300	Oreochromis niloticus	52.80	2.00e-129	458.00
IUUC-Oan-073046	Ornithorhynchus anatinus	52.91	4.00e-129	457.00
IUUC-Ocu-074178	Oryctolagus cuniculus	52.76	9.00e-131	462.00
IUUC-Osa-086200	Oryza sativa	59.53	0.00e+00	1083.00
IUUC-Oga-088903	Otolemur garnettii	53.16	3.00e-130	461.00
IUUC-Oar-090210	Ovis aries	53.16	4.00e-130	460.00
IUUC-Pan-092368	Papio anubis	52.42	5.00e-117	417.00
IUUC-Pno-094871	Phaeosphaeria nodorum	31.93	7.00e-141	496.00
IUUC-Ppa-095657	Physcomitrella patens	53.94	0.00e+00	1826.00
IUUC-Pab-098583	Pongo abelii	53.16	3.00e-130	461.00
IUUC-Pva-102116	Pteropus vampyrus	49.30	2.00e-116	415.00
IUUC-Pte-104018	Pyrenophora teres	32.60	1.00e-139	492.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	32.83	3.00e-141	497.00
IUUC-Sha-106961	Sarcophilus harrisii	53.04	2.00e-130	461.00
IUUC-Sar-113291	Sorex araneus	52.86	3.00e-125	444.00
IUUC-Ssc-115754	Sus scrofa	53.16	3.00e-130	461.00
IUUC-Tru-118570	Takifugu rubripes	52.80	1.00e-129	459.00
IUUC-Tca-121646	Theobroma cacao	46.08	0.00e+00	1526.00
IUUC-Tae-125214	Triticum aestivum	47.35	0.00e+00	1113.00
IUUC-Ttr-129253	Tursiops truncatus	53.04	4.00e-130	460.00
IUUC-Vda-129886	Verticillium dahliae	38.86	3.00e-141	497.00
IUUC-Vpa-130708	Vicugna pacos	53.04	9.00e-130	459.00
IUUC-Xtr-132123	Xenopus tropicalis	49.20	2.00e-116	415.00
IUUC-Xma-133869	Xiphophorus maculatus	52.80	7.00e-130	459.00
IUUC-Zma-135595	Zea mays	42.32	0.00e+00	1312.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence