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Tag Content
UUCD2 ID IUUC-Mcc-055677
UUCD1 version UUC-MaM-00245
Ensembl Protein ID ENSMMUP00000033689.2
UniProt Accession F7G0E7; F7G0E7_MACMU
Genbank Protein ID ENSMMUP00000033689
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03030887
Gene Name UBR2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000005675.3 ENSMMUT00000040647.2 ENSMMUP00000033689.2
ENSMMUG00000005675.3 ENSMMUT00000007978.3 ENSMMUP00000007498.3
ENSMMUG00000005675.3 ENSMMUT00000040646.2 ENSMMUP00000033688.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/N-recognin/N-domain 2.50e-39 134.4 227 302
E3 activity/RING/RING 5.80e-09 37.4 1108 1213
E3 activity/N-recognin/UBR-box 1.90e-31 109.5 97 167
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/N-recognin/N-domain
   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea++fat++d++GRr+v++Gd+++ce+ak++i++n++++++ pLkV+v
   Q: 227  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTK-PLKVQV 302
           9*********************************************************************.****98 PP
   

   E3 activity/RING/RING
   S: 1    CaiC......................................ledf........kdgplvlpCgHvfhadClqkw............ 29
           C++C                                      +           ++g+++ +CgH++ha+C+q++            
   Q: 1108 CILCqeeqevkvesramvlaafvqrstvlsknrskfiqdpekY--DplfmhpdlSCGTHTSSCGHIMHAHCWQRYfdsvqakeqrrq 1192
           8888444444433333333333333333333333333333321..023444444558999*************************** PP
   S: 30   .....pglknssskefrCPlC 45
                + +++++++ef+CPlC
   Q: 1193 qrlrlHTSYDVENGEFLCPLC 1213
           ********************* PP
   

   E3 activity/N-recognin/UBR-box
   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCgrvfkvge +y+Cr+C+vd+t+vlC+eCf  ++H+dH+y++++sggggfCdCGdteAw++g++C+k++
   Q: 97   HLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHE 167
           68******************************************************************996 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MASELEPEVQ AIDRSLLECS AEEIAGKWLQ ATDLTREVYQ HLAHYVPKIY CRGPNPLPQK 60
EDMLAQHVLL GPMEWYLCGE DPAFGFPKLE QANKPSHLCG RVFKVGEPTY SCRDCAVDPT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055677|E3,N-domain;E3,RING;E3,UBR-box|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TACAACTCCC ACAATGCATT CGAGGGGCCC CGTATCAGGG CGCCACCTGT CTCCCGGCTT 60
TGCTGGGACG ACTACAGTAC CCAGAACGCC CTGCTTCGCC TCCTGGGTGT TATCGCCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055677|E3,N-domain;E3,RING;E3,UBR-box|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR
PROSITE

PS51157--ZF_UBR
Pfam

PF02617--ClpS
PF02207--zf-UBR
SMART

SM00396--ZnF_UBR1
Gene Ontology

GO:0000785--C:chromatin
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0007141--P:male meiosis I
GO:0032007--P:negative regulation of TOR signaling
GO:0007283--P:spermatogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG mcc:696507
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000949 Aegilops tauschii 27.37 2.00e-21 99.00
IUUC-Aml-001876 Ailuropoda melanoleuca 84.57 0.00e+00 2731.00
IUUC-Atr-002501 Amborella trichopoda 29.37 6.00e-28 120.00
IUUC-Apl-003828 Anas platyrhynchos 87.16 0.00e+00 3060.00
IUUC-Aca-005189 Anolis carolinensis 85.48 0.00e+00 3042.00
IUUC-Aly-005901 Arabidopsis lyrata 32.39 4.00e-26 114.00
IUUC-Ath-007148 Arabidopsis thaliana 30.99 7.00e-25 110.00
IUUC-Ago-007946 Ashbya gossypii 23.33 5.00e-22 101.00
IUUC-Afl-008479 Aspergillus flavus 23.10 1.00e-47 186.00
IUUC-Afu-008929 Aspergillus fumigatus 24.47 2.00e-55 212.00
IUUC-Ani-009334 Aspergillus nidulans 23.98 3.00e-50 195.00
IUUC-Ang-009550 Aspergillus niger 23.69 2.00e-48 188.00
IUUC-Aor-010124 Aspergillus oryzae 23.10 1.00e-47 186.00
IUUC-Ame-011917 Astyanax mexicanus 73.69 0.00e+00 2497.00
IUUC-Bta-012768 Bos taurus 92.65 0.00e+00 3252.00
IUUC-Bdi-014635 Brachypodium distachyon 25.87 2.00e-31 132.00
IUUC-Bol-015669 Brassica oleracea 31.45 1.00e-30 129.00
IUUC-Bra-017776 Brassica rapa 31.45 4.00e-31 131.00
IUUC-Cel-018476 Caenorhabditis elegans 31.90 2.00e-84 308.00
IUUC-Cja-019797 Callithrix jacchus 98.25 0.00e+00 2695.00
IUUC-Cfa-020950 Canis familiaris 96.13 0.00e+00 3356.00
IUUC-Cpo-022385 Cavia porcellus 92.88 0.00e+00 3280.00
IUUC-Csa-024082 Chlorocebus sabaeus 99.49 0.00e+00 3461.00
IUUC-Cho-025029 Choloepus hoffmanni 87.08 0.00e+00 2191.00
IUUC-Cin-025148 Ciona intestinalis 35.71 8.00e-138 484.00
IUUC-Csv-026296 Ciona savignyi 31.48 2.00e-20 93.60
IUUC-Cgl-026605 Colletotrichum gloeosporioides 23.21 4.00e-55 211.00
IUUC-Cne-026823 Cryptococcus neoformans 21.95 1.00e-38 156.00
IUUC-Dre-028343 Danio rerio 72.24 0.00e+00 2486.00
IUUC-Dno-030002 Dasypus novemcinctus 92.59 0.00e+00 1974.00
IUUC-Dor-030207 Dipodomys ordii 79.75 0.00e+00 1597.00
IUUC-Dse-031531 Dothistroma septosporum 24.15 4.00e-55 211.00
IUUC-Dme-031910 Drosophila melanogaster 34.76 0.00e+00 683.00
IUUC-Ete-033162 Echinops telfairi 84.68 0.00e+00 1385.00
IUUC-Eca-033454 Equus caballus 94.65 0.00e+00 3295.00
IUUC-Eeu-034783 Erinaceus europaeus 77.57 0.00e+00 1524.00
IUUC-Fca-036588 Felis catus 95.96 0.00e+00 3338.00
IUUC-Fal-036919 Ficedula albicollis 87.32 0.00e+00 3003.00
IUUC-Fso-038463 Fusarium solani 24.52 1.00e-43 172.00
IUUC-Gmo-039698 Gadus morhua 69.28 0.00e+00 1614.00
IUUC-Ggr-040070 Gaeumannomyces graminis 22.88 3.00e-43 172.00
IUUC-Gga-041123 Gallus gallus 88.72 0.00e+00 3125.00
IUUC-Gac-042622 Gasterosteus aculeatus 66.04 0.00e+00 2207.00
IUUC-Gma-043622 Glycine max 30.39 3.00e-26 115.00
IUUC-Ggo-045583 Gorilla gorilla 97.45 0.00e+00 3413.00
IUUC-Hsa-046343 Homo sapiens 97.95 0.00e+00 3410.00
IUUC-Hvu-047626 Hordeum vulgare 29.33 6.00e-28 120.00
IUUC-Kpa-049088 Komagataella pastoris 23.17 9.00e-47 183.00
IUUC-Lch-049649 Latimeria chalumnae 74.93 0.00e+00 2605.00
IUUC-Lpe-051516 Leersia perrieri 26.02 4.00e-32 134.00
IUUC-Loc-052818 Lepisosteus oculatus 75.59 0.00e+00 2642.00
IUUC-Lma-053059 Leptosphaeria maculans 22.84 1.00e-48 189.00
IUUC-Laf-054142 Loxodonta africana 93.28 0.00e+00 3281.00
IUUC-Meu-056204 Macropus eugenii 68.35 0.00e+00 734.00
IUUC-Mor-057051 Magnaporthe oryzae 23.39 1.00e-50 196.00
IUUC-Mpo-057372 Magnaporthe poae 24.65 5.00e-45 177.00
IUUC-Mtr-058538 Medicago truncatula 30.39 8.00e-29 124.00
IUUC-Mla-058963 Melampsora laricipopulina 25.24 4.00e-57 218.00
IUUC-Mga-059698 Meleagris gallopavo 88.84 0.00e+00 3097.00
IUUC-Mvi-060535 Microbotryum violaceum 24.69 2.00e-50 196.00
IUUC-Mmr-060901 Microcebus murinus 93.11 0.00e+00 3239.00
IUUC-Mdo-062014 Monodelphis domestica 91.45 0.00e+00 3223.00
IUUC-Mmu-063699 Mus musculus 89.86 0.00e+00 3157.00
IUUC-Mac-064773 Musa acuminata 31.10 2.00e-27 119.00
IUUC-Mpu-066153 Mustela putorius furo 96.24 0.00e+00 3358.00
IUUC-Mlu-068151 Myotis lucifugus 93.17 0.00e+00 3242.00
IUUC-Nfi-068403 Neosartorya fischeri 23.95 1.00e-54 209.00
IUUC-Ncr-068864 Neurospora crassa 22.88 1.00e-42 170.00
IUUC-Nle-069529 Nomascus leucogenys 99.15 0.00e+00 3452.00
IUUC-Opr-071107 Ochotona princeps 88.30 0.00e+00 1358.00
IUUC-Ont-072189 Oreochromis niloticus 66.74 0.00e+00 2177.00
IUUC-Oan-072893 Ornithorhynchus anatinus 88.77 0.00e+00 3125.00
IUUC-Ocu-074082 Oryctolagus cuniculus 92.42 0.00e+00 3236.00
IUUC-Obr-076117 Oryza brachyantha 25.88 3.00e-27 119.00
IUUC-Ogl-077571 Oryza glaberrima 28.15 1.00e-20 96.30
IUUC-Olo-081056 Oryza longistaminata 25.34 3.00e-16 82.00
IUUC-Ome-081738 Oryza meridionalis 22.68 8.00e-15 77.40
IUUC-Opu-083202 Oryza punctata 26.82 1.00e-27 119.00
IUUC-Osa-085336 Oryza sativa 28.45 7.00e-21 96.30
IUUC-Ola-087460 Oryzias latipes 64.41 0.00e+00 2158.00
IUUC-Oga-088432 Otolemur garnettii 94.19 0.00e+00 3322.00
IUUC-Oar-090206 Ovis aries 92.69 0.00e+00 3271.00
IUUC-Ptr-091180 Pan troglodytes 97.72 0.00e+00 3409.00
IUUC-Pan-092375 Papio anubis 99.49 0.00e+00 3461.00
IUUC-Psi-093049 Pelodiscus sinensis 88.10 0.00e+00 3075.00
IUUC-Pma-094152 Petromyzon marinus 47.82 0.00e+00 661.00
IUUC-Pno-094877 Phaeosphaeria nodorum 24.43 1.00e-32 136.00
IUUC-Ppa-095715 Physcomitrella patens 28.99 1.00e-23 106.00
IUUC-Pfo-096524 Poecilia formosa 63.60 0.00e+00 2058.00
IUUC-Pab-097989 Pongo abelii 97.21 0.00e+00 3360.00
IUUC-Pca-100207 Procavia capensis 80.05 0.00e+00 1263.00
IUUC-Ppe-101802 Prunus persica 28.52 3.00e-26 115.00
IUUC-Pva-102538 Pteropus vampyrus 93.41 0.00e+00 1224.00
IUUC-Pgr-103372 Puccinia graminis 24.45 6.00e-53 204.00
IUUC-Ptt-103878 Puccinia triticina 24.08 1.00e-49 193.00
IUUC-Rno-105567 Rattus norvegicus 89.81 0.00e+00 3099.00
IUUC-Sce-106272 Saccharomyces cerevisiae 20.92 2.00e-25 112.00
IUUC-Sha-106980 Sarcophilus harrisii 90.90 0.00e+00 3078.00
IUUC-Sja-107980 Schizosaccharomyces japonicus 23.56 2.00e-47 185.00
IUUC-Spo-108183 Schizosaccharomyces pombe 25.22 9.00e-51 196.00
IUUC-Smo-108719 Selaginella moellendorffii 31.54 2.00e-30 129.00
IUUC-Sit-110716 Setaria italica 26.74 6.00e-33 137.00
IUUC-Sly-111286 Solanum lycopersicum 31.67 6.00e-27 117.00
IUUC-Sar-113332 Sorex araneus 87.27 0.00e+00 2197.00
IUUC-Sbi-114577 Sorghum bicolor 28.73 1.00e-30 129.00
IUUC-Sre-115045 Sporisorium reilianum 26.31 2.00e-46 182.00
IUUC-Ssc-115525 Sus scrofa 95.25 0.00e+00 2579.00
IUUC-Tgu-116943 Taeniopygia guttata 88.45 0.00e+00 3108.00
IUUC-Tru-117673 Takifugu rubripes 65.72 0.00e+00 2199.00
IUUC-Tsy-119032 Tarsius syrichta 93.45 0.00e+00 1847.00
IUUC-Tni-119987 Tetraodon nigroviridis 65.26 0.00e+00 2150.00
IUUC-Tca-121077 Theobroma cacao 32.70 2.00e-26 115.00
IUUC-Tre-122137 Trichoderma reesei 24.72 1.00e-58 223.00
IUUC-Tvi-122272 Trichoderma virens 23.11 2.00e-55 212.00
IUUC-Tae-125358 Triticum aestivum 29.45 2.00e-21 99.00
IUUC-Tur-126562 Triticum urartu 30.36 3.00e-28 121.00
IUUC-Tme-127156 Tuber melanosporum 23.39 2.00e-51 199.00
IUUC-Tbe-128103 Tupaia belangeri 87.53 0.00e+00 1249.00
IUUC-Ttr-128253 Tursiops truncatus 89.00 0.00e+00 3071.00
IUUC-Uma-129344 Ustilago maydis 26.60 5.00e-51 197.00
IUUC-Vda-129778 Verticillium dahliae 23.73 9.00e-48 186.00
IUUC-Vpa-130540 Vicugna pacos 90.83 0.00e+00 2966.00
IUUC-Vvi-131290 Vitis vinifera 33.02 2.00e-28 122.00
IUUC-Xtr-132690 Xenopus tropicalis 80.14 0.00e+00 2841.00
IUUC-Xma-133748 Xiphophorus maculatus 64.73 0.00e+00 2030.00
IUUC-Yli-134662 Yarrowia lipolytica 23.66 1.00e-30 129.00
IUUC-Zma-135553 Zea mays 22.70 1.00e-16 83.60
Created Date 25-Jun-2017

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