iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020263

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03026338

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000015620.3	ENSCAFT00000024781.3	ENSCAFP00000022990.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	77.50	0.00e+00	1741.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

PTPQSRIRGE VSPTMTSTGQ DSTTTRQRRS RHNPHSPPHD SSVTSKRGVK KGALRHSSPS 60
LAEVKKKGRM KKLSQAAEQD LIVGLQGLDL NLEAKTLCGT GLVFDEQLNE FHCLWDDSFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCACCCCCC AGAGCCGCAT CAGGGGTGAA GTCTCCCCGA CCATGACCTC CACCGGCCAG 60
GATTCCACCA CAACCAGGCA GCGAAGGAGT AGGCATAACC CCCATTCGCC CCCCCACGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	41.56	2.00e-71	263.00
IUUC-Aml-002087	Ailuropoda melanoleuca	88.93	0.00e+00	2023.00
IUUC-Atr-002745	Amborella trichopoda	43.18	5.00e-84	305.00
IUUC-Aca-004303	Anolis carolinensis	57.98	0.00e+00	1004.00
IUUC-Aly-006432	Arabidopsis lyrata	45.00	3.00e-83	303.00
IUUC-Ath-007355	Arabidopsis thaliana	45.05	5.00e-87	315.00
IUUC-Ago-007972	Ashbya gossypii	40.96	2.00e-80	293.00
IUUC-Acl-008187	Aspergillus clavatus	44.30	1.00e-86	314.00
IUUC-Afl-008399	Aspergillus flavus	48.29	3.00e-49	189.00
IUUC-Afu-008954	Aspergillus fumigatus	40.89	9.00e-76	278.00
IUUC-Ani-009142	Aspergillus nidulans	43.53	8.00e-79	288.00
IUUC-Ang-009522	Aspergillus niger	35.73	1.00e-49	191.00
IUUC-Aor-010069	Aspergillus oryzae	43.42	3.00e-77	283.00
IUUC-Ate-010291	Aspergillus terreus	44.12	8.00e-86	311.00
IUUC-Ame-010780	Astyanax mexicanus	51.01	0.00e+00	780.00
IUUC-Bta-013052	Bos taurus	79.25	0.00e+00	1760.00
IUUC-Bci-013789	Botrytis cinerea	39.49	2.00e-75	276.00
IUUC-Bdi-014007	Brachypodium distachyon	43.45	2.00e-85	310.00
IUUC-Bol-015468	Brassica oleracea	43.98	6.00e-85	308.00
IUUC-Bra-016680	Brassica rapa	44.24	2.00e-85	310.00
IUUC-Cel-018220	Caenorhabditis elegans	38.31	2.00e-147	516.00
IUUC-Cja-019473	Callithrix jacchus	75.86	0.00e+00	1725.00
IUUC-Cpo-021691	Cavia porcellus	79.74	0.00e+00	1795.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	55.07	9.00e-57	213.00
IUUC-Csa-024223	Chlorocebus sabaeus	85.01	0.00e+00	1582.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	40.31	3.00e-77	282.00
IUUC-Cne-026978	Cryptococcus neoformans	45.19	5.00e-91	328.00
IUUC-Dre-028820	Danio rerio	49.59	0.00e+00	1037.00
IUUC-Dno-029160	Dasypus novemcinctus	75.32	0.00e+00	1667.00
IUUC-Dor-030859	Dipodomys ordii	70.77	0.00e+00	1621.00
IUUC-Dse-031186	Dothistroma septosporum	40.25	7.00e-80	291.00
IUUC-Dme-031963	Drosophila melanogaster	43.11	0.00e+00	684.00
IUUC-Ete-032279	Echinops telfairi	66.59	5.00e-157	548.00
IUUC-Eca-033842	Equus caballus	84.59	0.00e+00	1947.00
IUUC-Eeu-034487	Erinaceus europaeus	77.30	1.00e-157	550.00
IUUC-Fca-036430	Felis catus	88.11	0.00e+00	1959.00
IUUC-Fox-038067	Fusarium oxysporum	41.60	2.00e-80	293.00
IUUC-Fso-038263	Fusarium solani	41.86	2.00e-81	296.00
IUUC-Ggr-040062	Gaeumannomyces graminis	40.60	8.00e-73	268.00
IUUC-Gma-043738	Glycine max	45.43	3.00e-86	313.00
IUUC-Ggo-045022	Gorilla gorilla	81.43	0.00e+00	1578.00
IUUC-Hsa-046904	Homo sapiens	77.63	0.00e+00	1755.00
IUUC-Hvu-047285	Hordeum vulgare	46.13	1.00e-84	306.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	80.86	0.00e+00	1860.00
IUUC-Kpa-049281	Komagataella pastoris	40.92	4.00e-84	305.00
IUUC-Lch-050330	Latimeria chalumnae	46.83	0.00e+00	956.00
IUUC-Lpe-051214	Leersia perrieri	38.63	3.00e-87	316.00
IUUC-Lma-053263	Leptosphaeria maculans	40.08	4.00e-89	322.00
IUUC-Laf-053386	Loxodonta africana	79.34	0.00e+00	1780.00
IUUC-Mcc-055530	Macaca mulatta	85.11	0.00e+00	1571.00
IUUC-Meu-056442	Macropus eugenii	67.59	0.00e+00	969.00
IUUC-Mor-057095	Magnaporthe oryzae	39.80	1.00e-83	304.00
IUUC-Mpo-057389	Magnaporthe poae	40.33	8.00e-73	268.00
IUUC-Mtr-058463	Medicago truncatula	43.45	2.00e-88	319.00
IUUC-Mla-059143	Melampsora laricipopulina	44.28	3.00e-83	303.00
IUUC-Mmr-060637	Microcebus murinus	79.09	0.00e+00	1862.00
IUUC-Mdo-062198	Monodelphis domestica	67.08	0.00e+00	1075.00
IUUC-Mmu-063346	Mus musculus	74.70	0.00e+00	1697.00
IUUC-Mac-064630	Musa acuminata	44.65	1.00e-82	300.00
IUUC-Mpu-065884	Mustela putorius furo	88.52	0.00e+00	2017.00
IUUC-Mlu-068117	Myotis lucifugus	81.35	0.00e+00	1815.00
IUUC-Nfi-068404	Neosartorya fischeri	43.54	2.00e-86	313.00
IUUC-Ncr-068672	Neurospora crassa	41.34	1.00e-80	294.00
IUUC-Nle-069868	Nomascus leucogenys	92.47	0.00e+00	746.00
IUUC-Opr-071074	Ochotona princeps	66.46	0.00e+00	1035.00
IUUC-Ont-072246	Oreochromis niloticus	46.78	0.00e+00	944.00
IUUC-Oan-072911	Ornithorhynchus anatinus	61.69	2.00e-108	387.00
IUUC-Ocu-074627	Oryctolagus cuniculus	79.61	0.00e+00	1851.00
IUUC-Oba-075489	Oryza barthii	45.85	1.00e-84	307.00
IUUC-Obr-076150	Oryza brachyantha	45.68	1.00e-84	307.00
IUUC-Ogl-077437	Oryza glaberrima	43.10	3.00e-85	309.00
IUUC-Ogu-078370	Oryza glumaepatula	43.38	6.00e-86	311.00
IUUC-Oin-079210	Oryza indica	43.38	5.00e-86	312.00
IUUC-Olo-080971	Oryza longistaminata	46.95	2.00e-74	273.00
IUUC-Oni-082031	Oryza nivara	43.38	6.00e-86	311.00
IUUC-Opu-083471	Oryza punctata	45.23	2.00e-84	306.00
IUUC-Oru-084755	Oryza rufipogon	43.38	7.00e-86	311.00
IUUC-Osa-085447	Oryza sativa	43.38	6.00e-86	311.00
IUUC-Oga-089155	Otolemur garnettii	78.24	0.00e+00	1808.00
IUUC-Oar-089620	Ovis aries	79.07	0.00e+00	1779.00
IUUC-Ptr-090812	Pan troglodytes	88.59	0.00e+00	1259.00
IUUC-Pan-092340	Papio anubis	84.90	0.00e+00	1566.00
IUUC-Pma-094386	Petromyzon marinus	53.29	0.00e+00	805.00
IUUC-Pno-095131	Phaeosphaeria nodorum	48.06	1.00e-75	277.00
IUUC-Ppa-095550	Physcomitrella patens	46.83	1.00e-88	321.00
IUUC-Pfo-096110	Poecilia formosa	55.61	0.00e+00	720.00
IUUC-Pab-098422	Pongo abelii	84.14	0.00e+00	1538.00
IUUC-Pop-099174	Populus trichocarpa	41.90	1.00e-81	297.00
IUUC-Pca-100833	Procavia capensis	75.53	0.00e+00	1597.00
IUUC-Ppe-101644	Prunus persica	41.58	9.00e-87	314.00
IUUC-Pva-102410	Pteropus vampyrus	79.43	0.00e+00	1746.00
IUUC-Ptt-103841	Puccinia triticina	39.54	4.00e-80	292.00
IUUC-Pte-104383	Pyrenophora teres	43.58	3.00e-85	310.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	44.12	6.00e-86	311.00
IUUC-Rno-105131	Rattus norvegicus	73.68	0.00e+00	1688.00
IUUC-Sce-106274	Saccharomyces cerevisiae	39.49	2.00e-79	290.00
IUUC-Sha-106661	Sarcophilus harrisii	55.37	0.00e+00	815.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	42.59	2.00e-87	317.00
IUUC-Spo-108300	Schizosaccharomyces pombe	45.78	7.00e-88	318.00
IUUC-Smo-109615	Selaginella moellendorffii	44.17	2.00e-86	313.00
IUUC-Sit-110160	Setaria italica	42.86	5.00e-81	295.00
IUUC-Sly-111164	Solanum lycopersicum	39.61	5.00e-81	295.00
IUUC-Stu-112685	Solanum tuberosum	41.96	5.00e-70	258.00
IUUC-Sar-113692	Sorex araneus	69.40	0.00e+00	804.00
IUUC-Sbi-114301	Sorghum bicolor	46.18	2.00e-80	293.00
IUUC-Sre-115013	Sporisorium reilianum	43.57	3.00e-81	296.00
IUUC-Ssc-115724	Sus scrofa	82.34	0.00e+00	1751.00
IUUC-Tgu-116605	Taeniopygia guttata	47.86	0.00e+00	680.00
IUUC-Tru-117614	Takifugu rubripes	54.49	0.00e+00	847.00
IUUC-Tsy-118807	Tarsius syrichta	75.95	0.00e+00	849.00
IUUC-Tni-119809	Tetraodon nigroviridis	55.51	0.00e+00	797.00
IUUC-Tca-121312	Theobroma cacao	42.78	2.00e-84	306.00
IUUC-Tre-121930	Trichoderma reesei	40.59	2.00e-82	300.00
IUUC-Tvi-122373	Trichoderma virens	41.34	2.00e-82	300.00
IUUC-Tae-123064	Triticum aestivum	40.96	2.00e-77	283.00
IUUC-Tme-127027	Tuber melanosporum	41.42	3.00e-70	258.00
IUUC-Tbe-127675	Tupaia belangeri	51.44	2.00e-86	314.00
IUUC-Ttr-128411	Tursiops truncatus	81.79	0.00e+00	1865.00
IUUC-Uma-129408	Ustilago maydis	47.40	4.00e-76	279.00
IUUC-Vda-129994	Verticillium dahliae	38.57	1.00e-74	274.00
IUUC-Vpa-130525	Vicugna pacos	68.63	8.00e-66	245.00
IUUC-Vvi-131038	Vitis vinifera	41.74	3.00e-85	309.00
IUUC-Xtr-132618	Xenopus tropicalis	50.78	0.00e+00	1086.00
IUUC-Xma-133730	Xiphophorus maculatus	49.69	0.00e+00	713.00
IUUC-Yli-134680	Yarrowia lipolytica	41.61	2.00e-86	313.00
IUUC-Zma-135110	Zea mays	44.64	6.00e-81	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence