iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040624

UUCD1 version

UUC-GaG-00884

Ensembl Protein ID

ENSGALP00000056329.1

UniProt Accession

A0A1D5PTS9; A0A1D5PTS9_CHICK

Genbank Protein ID

ENSGALP00000056329

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AADN04000130

Gene Name

USP22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000029817.1	ENSGALT00000065999.1	ENSGALP00000056329.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.50e-93	312.5	177	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ +++k++ +   +p+ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 177  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHKCEMQ---SPSSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQ 261
           9*****************************.99999975...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 262  DAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGS 334
           *****************22................22335677899999**************************************** PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           ++   +                    +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf  +++ k r+k
   Q: 335  STPFWPlspgsdgsvvngeshvsgttTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 421
           *87777************************************************************************..5666899** PP
   S: 249  inkkvefpleLdlspfcts............peekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
           i+++v+fpleLd++pf++s            p+++ ++++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + ++vl  
   Q: 422  ITTYVSFPLELDMTPFMASskesrmngqyqqPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLD- 509
           *******************5555555555554445555**************************************************. PP
   S: 326  tgstaYvlfYkrr 338
             s++Y+lfY+++
   Q: 510  --SEGYLLFYHKQ 520
           ..********985 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MSPPAAGCCH VTGFKVENWK QNLRAIYQCF VWSGSAETRK RKAKSCICHM CGAHLNRLHS 60
CLYCVFFGCF TKKHIHEHAK TKRHNLAIDL LYGGIYCFMC QDYIYDKDME QIAKEEQRKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGTCTGA CATGAGTCCG CCGGCGGCCG GGTGCTGCCA TGTGACCGGC TTCAAGGTGG 60
AGAACTGGAA GCAGAACCTG AGGGCCATTT ACCAGTGCTT CGTGTGGAGC GGTTCGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	37.57	1.00e-64	240.00
IUUC-Aml-001343	Ailuropoda melanoleuca	90.29	0.00e+00	1005.00
IUUC-Atr-002653	Amborella trichopoda	36.50	2.00e-98	353.00
IUUC-Apl-003433	Anas platyrhynchos	99.79	0.00e+00	1015.00
IUUC-Aca-005347	Anolis carolinensis	95.93	0.00e+00	1087.00
IUUC-Aly-006565	Arabidopsis lyrata	36.13	2.00e-70	259.00
IUUC-Ath-007536	Arabidopsis thaliana	35.48	5.00e-70	258.00
IUUC-Ago-007811	Ashbya gossypii	29.67	2.00e-51	196.00
IUUC-Acl-008124	Aspergillus clavatus	31.24	4.00e-57	215.00
IUUC-Afl-008464	Aspergillus flavus	32.33	4.00e-54	205.00
IUUC-Afu-008912	Aspergillus fumigatus	30.56	4.00e-54	205.00
IUUC-Ani-009168	Aspergillus nidulans	31.24	9.00e-57	214.00
IUUC-Ang-009694	Aspergillus niger	30.60	3.00e-55	208.00
IUUC-Aor-010035	Aspergillus oryzae	35.21	1.00e-38	152.00
IUUC-Ate-010382	Aspergillus terreus	31.63	4.00e-52	198.00
IUUC-Ame-011253	Astyanax mexicanus	85.19	0.00e+00	843.00
IUUC-Bgr-012150	Blumeria graminis	30.69	2.00e-47	183.00
IUUC-Bta-013303	Bos taurus	91.24	0.00e+00	1011.00
IUUC-Bci-013604	Botrytis cinerea	31.92	6.00e-56	211.00
IUUC-Bdi-014171	Brachypodium distachyon	35.15	1.00e-76	280.00
IUUC-Bol-016509	Brassica oleracea	37.24	1.00e-73	271.00
IUUC-Bra-016962	Brassica rapa	35.80	4.00e-71	261.00
IUUC-Cja-019283	Callithrix jacchus	93.17	0.00e+00	862.00
IUUC-Cfa-021239	Canis familiaris	92.39	0.00e+00	949.00
IUUC-Cpo-022354	Cavia porcellus	91.43	0.00e+00	1010.00
IUUC-Csa-023145	Chlorocebus sabaeus	92.00	0.00e+00	1018.00
IUUC-Cho-024938	Choloepus hoffmanni	80.15	7.00e-61	227.00
IUUC-Cin-025109	Ciona intestinalis	55.41	3.00e-121	428.00
IUUC-Csv-026214	Ciona savignyi	54.16	1.00e-172	599.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	31.07	2.00e-53	203.00
IUUC-Cne-027085	Cryptococcus neoformans	32.20	1.00e-63	237.00
IUUC-Dre-027433	Danio rerio	93.37	0.00e+00	934.00
IUUC-Dno-030095	Dasypus novemcinctus	92.56	0.00e+00	949.00
IUUC-Dor-030832	Dipodomys ordii	86.08	7.00e-98	350.00
IUUC-Dse-031415	Dothistroma septosporum	29.82	7.00e-60	224.00
IUUC-Dme-032074	Drosophila melanogaster	50.18	2.00e-136	479.00
IUUC-Ete-033175	Echinops telfairi	73.10	0.00e+00	679.00
IUUC-Eca-033736	Equus caballus	92.15	0.00e+00	942.00
IUUC-Eeu-034814	Erinaceus europaeus	98.57	1.00e-122	432.00
IUUC-Fca-035861	Felis catus	92.77	0.00e+00	950.00
IUUC-Fal-037645	Ficedula albicollis	100.00	0.00e+00	1001.00
IUUC-Fox-038046	Fusarium oxysporum	31.10	2.00e-54	206.00
IUUC-Fso-038321	Fusarium solani	31.87	4.00e-54	205.00
IUUC-Gmo-038474	Gadus morhua	95.27	9.00e-173	599.00
IUUC-Ggr-040044	Gaeumannomyces graminis	31.14	1.00e-54	207.00
IUUC-Gac-042197	Gasterosteus aculeatus	87.64	0.00e+00	948.00
IUUC-Gma-043933	Glycine max	35.55	2.00e-87	316.00
IUUC-Ggo-044409	Gorilla gorilla	92.00	0.00e+00	1021.00
IUUC-Hsa-046521	Homo sapiens	92.00	0.00e+00	1019.00
IUUC-Hvu-047739	Hordeum vulgare	38.67	2.00e-69	256.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	91.24	0.00e+00	1011.00
IUUC-Kpa-049135	Komagataella pastoris	34.03	1.00e-66	246.00
IUUC-Lch-050537	Latimeria chalumnae	93.90	0.00e+00	1030.00
IUUC-Lpe-050969	Leersia perrieri	38.37	2.00e-73	269.00
IUUC-Loc-052765	Lepisosteus oculatus	85.87	0.00e+00	927.00
IUUC-Lma-053105	Leptosphaeria maculans	32.94	3.00e-64	239.00
IUUC-Laf-053571	Loxodonta africana	93.39	0.00e+00	952.00
IUUC-Mcc-055166	Macaca mulatta	92.00	0.00e+00	1018.00
IUUC-Mor-057103	Magnaporthe oryzae	30.55	7.00e-56	211.00
IUUC-Mpo-057621	Magnaporthe poae	31.57	1.00e-54	207.00
IUUC-Mtr-057894	Medicago truncatula	36.96	2.00e-85	309.00
IUUC-Mla-059185	Melampsora laricipopulina	33.15	7.00e-42	164.00
IUUC-Mga-059709	Meleagris gallopavo	99.79	0.00e+00	1015.00
IUUC-Mvi-060530	Microbotryum violaceum	33.78	3.00e-58	219.00
IUUC-Mmr-060988	Microcebus murinus	91.81	0.00e+00	1020.00
IUUC-Mdo-063065	Monodelphis domestica	95.43	0.00e+00	1042.00
IUUC-Mmu-063829	Mus musculus	91.05	0.00e+00	1015.00
IUUC-Mac-065419	Musa acuminata	39.84	6.00e-72	264.00
IUUC-Mpu-066687	Mustela putorius furo	91.05	0.00e+00	1007.00
IUUC-Mlu-067330	Myotis lucifugus	80.99	0.00e+00	890.00
IUUC-Nfi-068423	Neosartorya fischeri	30.56	3.00e-54	205.00
IUUC-Ncr-068809	Neurospora crassa	29.15	1.00e-56	213.00
IUUC-Nle-069261	Nomascus leucogenys	88.00	0.00e+00	964.00
IUUC-Opr-070469	Ochotona princeps	76.26	0.00e+00	674.00
IUUC-Ont-071961	Oreochromis niloticus	90.10	0.00e+00	979.00
IUUC-Oan-073565	Ornithorhynchus anatinus	92.59	0.00e+00	984.00
IUUC-Ocu-074435	Oryctolagus cuniculus	91.60	0.00e+00	988.00
IUUC-Oba-075688	Oryza barthii	35.48	2.00e-75	276.00
IUUC-Obr-076652	Oryza brachyantha	41.42	2.00e-74	272.00
IUUC-Ogl-077910	Oryza glaberrima	35.89	6.00e-80	291.00
IUUC-Ogu-078479	Oryza glumaepatula	35.89	6.00e-80	291.00
IUUC-Oin-079697	Oryza indica	39.41	1.00e-75	276.00
IUUC-Olo-080811	Oryza longistaminata	41.38	6.00e-53	200.00
IUUC-Ome-081706	Oryza meridionalis	35.89	2.00e-79	290.00
IUUC-Oni-083070	Oryza nivara	35.48	1.00e-79	290.00
IUUC-Opu-083605	Oryza punctata	39.89	3.00e-67	248.00
IUUC-Oru-084522	Oryza rufipogon	35.89	6.00e-80	291.00
IUUC-Osa-085351	Oryza sativa	39.36	2.00e-76	280.00
IUUC-Ola-086743	Oryzias latipes	86.09	0.00e+00	751.00
IUUC-Olu-087695	Ostreococcus lucimarinus	32.08	1.00e-50	193.00
IUUC-Oga-089131	Otolemur garnettii	91.63	0.00e+00	1019.00
IUUC-Oar-089319	Ovis aries	92.55	0.00e+00	943.00
IUUC-Ptr-090783	Pan troglodytes	90.44	0.00e+00	954.00
IUUC-Pan-092927	Papio anubis	91.81	0.00e+00	1017.00
IUUC-Psi-093670	Pelodiscus sinensis	100.00	0.00e+00	1015.00
IUUC-Pma-094323	Petromyzon marinus	67.61	0.00e+00	709.00
IUUC-Pno-095141	Phaeosphaeria nodorum	30.78	2.00e-54	206.00
IUUC-Ppa-095413	Physcomitrella patens	34.78	2.00e-84	306.00
IUUC-Pfo-096462	Poecilia formosa	89.81	0.00e+00	997.00
IUUC-Pab-097612	Pongo abelii	92.00	0.00e+00	1020.00
IUUC-Pop-099558	Populus trichocarpa	35.53	3.00e-86	312.00
IUUC-Pca-100329	Procavia capensis	81.18	0.00e+00	891.00
IUUC-Ppe-102020	Prunus persica	36.49	3.00e-92	332.00
IUUC-Pva-102721	Pteropus vampyrus	77.19	0.00e+00	833.00
IUUC-Pgr-103657	Puccinia graminis	30.24	1.00e-37	150.00
IUUC-Pte-104340	Pyrenophora teres	32.09	2.00e-57	216.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	34.67	2.00e-64	239.00
IUUC-Rno-105247	Rattus norvegicus	91.24	0.00e+00	1014.00
IUUC-Sce-106247	Saccharomyces cerevisiae	30.82	8.00e-51	194.00
IUUC-Sha-107538	Sarcophilus harrisii	97.24	7.00e-126	442.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	33.47	3.00e-66	245.00
IUUC-Spo-108226	Schizosaccharomyces pombe	31.70	1.00e-60	226.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	31.36	1.00e-53	204.00
IUUC-Smo-109310	Selaginella moellendorffii	34.89	7.00e-87	314.00
IUUC-Sit-109716	Setaria italica	35.41	2.00e-79	289.00
IUUC-Sly-111077	Solanum lycopersicum	36.64	3.00e-79	288.00
IUUC-Stu-112203	Solanum tuberosum	38.26	1.00e-72	266.00
IUUC-Sar-113174	Sorex araneus	79.18	0.00e+00	810.00
IUUC-Sbi-114205	Sorghum bicolor	35.07	2.00e-80	293.00
IUUC-Sre-115195	Sporisorium reilianum	33.46	3.00e-30	126.00
IUUC-Ssc-115315	Sus scrofa	82.70	0.00e+00	915.00
IUUC-Tgu-116938	Taeniopygia guttata	96.69	0.00e+00	974.00
IUUC-Tru-117622	Takifugu rubripes	92.00	0.00e+00	1014.00
IUUC-Tsy-119431	Tarsius syrichta	80.95	0.00e+00	795.00
IUUC-Tni-120119	Tetraodon nigroviridis	91.24	0.00e+00	1002.00
IUUC-Tca-121716	Theobroma cacao	34.18	3.00e-85	309.00
IUUC-Tre-122139	Trichoderma reesei	31.28	2.00e-53	202.00
IUUC-Tvi-122599	Trichoderma virens	30.97	4.00e-54	205.00
IUUC-Tae-125608	Triticum aestivum	35.76	1.00e-87	317.00
IUUC-Tme-127115	Tuber melanosporum	35.61	2.00e-79	289.00
IUUC-Ttr-129006	Tursiops truncatus	81.59	0.00e+00	880.00
IUUC-Uma-129455	Ustilago maydis	33.58	2.00e-32	134.00
IUUC-Vda-129829	Verticillium dahliae	33.22	2.00e-35	142.00
IUUC-Vvi-131477	Vitis vinifera	35.85	1.00e-77	283.00
IUUC-Xtr-132444	Xenopus tropicalis	95.43	0.00e+00	1056.00
IUUC-Xma-133514	Xiphophorus maculatus	92.38	0.00e+00	1013.00
IUUC-Yli-134357	Yarrowia lipolytica	30.52	4.00e-48	185.00
IUUC-Zma-134945	Zea mays	35.15	2.00e-77	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence